(Q40911261)

24 September 2017

Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B. (English)

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24 September 2017

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P Smart

1

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24 September 2017

E B Lane

2

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24 September 2017

D P Lane

3

1 reference

24 September 2017

C Midgley

4

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24 September 2017

B Vojtesek

5

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24 September 2017

S Laín

6

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24 September 2017

language of work or name

English

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publication date

1 December 1999

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24 September 2017

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24 September 2017

18

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24 September 2017

51

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24 September 2017

7378-7386

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203260

24 September 2017

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cites work

Mechanisms of p53-mediated apoptosis

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7 January 2021

Mapping of the p53 and mdm-2 interaction domains

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7 January 2021

Cell cycle kinetics following UVA irradiation in comparison to UVB and UVC irradiation

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7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Functions of the MDM2 oncoprotein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Limitation of therapy in the treatment of childhood cancer: toxicity versus cure

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Cell-cycle regulators and cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Nucleocytoplasmic transport: the soluble phase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Phase I trial of elactocin

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721).

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Novel antitumor antibiotics, CI-940 (PD 114,720) and PD 114,721. Taxonomy, fermentation and biological activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203260

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203260

1 reference

Dimensions Publication ID

24 September 2017

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1 reference