(Q40918502)

24 September 2017

Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway (English)

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24 September 2017

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Rodriguez A

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24 September 2017

Oliver H

2

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24 September 2017

Zou H

3

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24 September 2017

Chen P

4

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24 September 2017

Wang X

5

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24 September 2017

Abrams JM

6

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24 September 2017

language of work or name

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1 September 1999

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24 September 2017

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24 September 2017

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24 September 2017

272-279

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24 September 2017

5

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https://scigraph.springernature.com/pub.10.1038/12984

24 September 2017

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cites work

Programmed cell death in animal development

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7 January 2021

Apoptosis in the pathogenesis and treatment of disease

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7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

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7 January 2021

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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7 January 2021

Cell Death in Development

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7 January 2021

Interaction and regulation of subcellular localization of CED-4 by CED-9

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7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

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7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

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7 January 2021

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

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7 January 2021

Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

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7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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7 January 2021

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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7 January 2021

Genetic control of programmed cell death in Drosophila

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7 January 2021

grim, a novel cell death gene in Drosophila

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7 January 2021

The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

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7 January 2021

DCP-1, a Drosophila cell death protease essential for development.

1 reference

7 January 2021

Identification of a Drosophila melanogaster ICE/CED-3-related protease, drICE.

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7 January 2021

Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.

1 reference

7 January 2021

DRONC, an ecdysone-inducible Drosophila caspase

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7 January 2021

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

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7 January 2021

Facing death in the fly: genetic analysis of apoptosis in Drosophila

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7 January 2021

Molecular prophets of death in the fly.

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7 January 2021

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7 January 2021

The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals

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7 January 2021

The CARD domain: a new apoptotic signalling motif

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7 January 2021

Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment

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7 January 2021

Mutations in the Drosophila hook gene inhibit endocytosis of the boss transmembrane ligand into multivesicular bodies

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7 January 2021

Cytochrome c: can't live with it--can't live without it.

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7 January 2021

Mitochondria and apoptosis

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7 January 2021

Altered cytochrome c display precedes apoptotic cell death in Drosophila

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7 January 2021

Lethal(1) aberrant immune response mutations leading to melanotic tumor formation in Drosophila melanogaster

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7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

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7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

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7 January 2021

The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

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7 January 2021

Ras promotes cell survival in Drosophila by downregulating hid expression.

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7 January 2021

Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9.

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7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

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7 January 2021

Boo, a novel negative regulator of cell death, interacts with Apaf-1.

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7 January 2021

Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death

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7 January 2021

The engrailed locus of Drosophila: structural analysis of an embryonic transcript

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7 January 2021

Characterization and use of the Drosophila metallothionein promoter in cultured Drosophila melanogaster cells

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7 January 2021

Hormone-dependent transactivation by estrogen receptor chimeras that do not interact with hsp90. Evidence for transcriptional repressors

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7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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7 January 2021

Identifiers

DOI

10.1038/12984

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24 September 2017

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