(Q40918767)

24 September 2017

1 reference

title

Protein-drug complexes important for immunoregulation and organ transplantation (English)

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24 September 2017

main subject

organ transplantation

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Navia MA

1

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24 September 2017

publication date

1 December 1996

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Current Opinion in Structural Biology

24 September 2017

published in

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24 September 2017

volume

6

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24 September 2017

issue

6

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24 September 2017

page(s)

838-847

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Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Mechanisms of action of new immunosuppressive drugs.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Biological effects of cyclosporin A: A new antilymphocytic agent

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Elucidating the mechanism of action of the immunosuppressant 15-deoxyspergualin.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

T cell antigen receptor signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Intracellular receptors and signal transducers and activators of transcription superfamilies: novel targets for small-molecule drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Structural determinants of nuclear receptor assembly on DNA direct repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

The development of Brequinar as an immunosuppressive drug for transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Design, synthesis and structure of non-macrocyclic inhibitors of FKBP12, the major binding protein for the immunosuppressant FK506.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Structure-based design of novel, urea-containing FKBP12 inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Signal transmission between the plasma membrane and nucleus of T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Insights derived from the structures of the Ser/Thr phosphatases calcineurin and protein phosphatase 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

1 reference

7 January 2021

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Mechanism of action of the immunosuppressant rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Signal-transduction therapy. A novel approach to disease management

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Immunopharmacology of rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

p70 S6 kinase: an enigma with variations

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Hydroxyurea and AIDS: an old drug finds a new application?

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

Polymerase substrate depletion: a novel strategy for inhibiting the replication of the human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0959-440X%2896%2980015-7

7 January 2021

10.1016/S0959-440X(96)80015-7

Identifiers

DOI

1 reference

24 September 2017

1 reference