(Q40923094)

24 September 2017

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title

Gestodene. A review of its pharmacology, efficacy and tolerability in combined contraceptive preparations (English)

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24 September 2017

M I Wilde

1

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PubMed ID

8521763

24 September 2017

J A Balfour

series ordinal

2

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24 September 2017

1 August 1995

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24 September 2017

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24 September 2017

50

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24 September 2017

2

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24 September 2017

364-395

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https://scigraph.springernature.com/pub.10.2165/00003495-199550020-00010

24 September 2017

0 references

cites work

Coronary artery disease in women. Risk factors, evaluation, treatment, and prevention

1 reference

12 December 2020

Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes

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12 December 2020

A comparison of the effects of two monophasic low dose oral contraceptives on the inhibition of ovulation.

1 reference

12 December 2020

Metabolism of gestodene in human liver cytosol and microsomes in vitro

1 reference

12 December 2020

Influence of gestodene and desogestrel as components of low-dose oral contraceptives on the pharmacokinetics of ethinyl estradiol (EE2), on serum CBG and on urinary cortisol and 6 beta-hydroxycortisol.

1 reference

12 December 2020

Effects of contraceptive steroids on cardiovascular risk factors in women with insulin-dependent diabetes mellitus

1 reference

12 December 2020

Effects of seven low-dose combined contraceptives on vitamin B6 status

1 reference

12 December 2020

Clinical aspects of three new progestogens: desogestrel, gestodene, and norgestimate

1 reference

12 December 2020

Pulsatile luteinizing hormone secretion during the first and the fourth cycle on two different oral contraceptives containing gestodene

1 reference

12 December 2020

A comparative study on the effects of a monophasic pill containing desogestrel plus 20 μg ethinylestradiol, a triphasic combination containing levonorgestrel and a monophasic combination containing gestodene on coagulatory factors

1 reference

12 December 2020

Preclinical evaluation of norgestimate, a progestin with minimal androgenic activity

1 reference

12 December 2020

Six-month carbohydrate metabolism studies in women using oral contraceptives containing gestodene and ethinyl estradiol

1 reference

12 December 2020

Long-term experience with a low-dose oral contraceptive

1 reference

12 December 2020

[Gonadotropic function during its use and after its cessation of a triphasic combination of gestodene]

1 reference

12 December 2020

Insulin resistance, glucose intolerance, hyperinsulinemia and dyslipidemia in patients with angiographically demonstrated coronary artery disease

1 reference

12 December 2020

Haemostasis profile in smoking and nonsmoking women taking low-dose oral contraceptives

1 reference

12 December 2020

Comparative studies of 30 micrograms ethinyl estradiol combined with gestodene and desogestrel on blood coagulation, fibrinolysis, and platelets

1 reference

12 December 2020

Cerebrovascular disorders and administration of oral contraceptives containing gestodene--causal relation or coincidence?

1 reference

12 December 2020

Pharmacokinetics of gestodene and ethinyl estradiol after oral administration of a monophasic contraceptive

1 reference

12 December 2020

Effect of two oral contraceptives containing 30 micrograms ethinylestradiol and 75 micrograms gestodene or 150 micrograms desogestrel upon various hormonal parameters

1 reference

12 December 2020

Coronary heart disease risk factors in women

1 reference

12 December 2020

Single dose pharmacokinetics of gestodene in women after intravenous and oral administration.

1 reference

12 December 2020

Clinical acceptability of monophasic gestodene.

1 reference

12 December 2020

Effect of the progestogens, gestodene, 3-keto desogestrel, levonorgestrel, norethisterone and norgestimate on the oxidation of ethinyloestradiol and other substrates by human liver microsomes.

1 reference

12 December 2020

New progestogens in oral contraceptives

1 reference

12 December 2020

Oral contraception noncompliance: the extent of the problem

1 reference

12 December 2020

The new pills: awaiting the next generation of oral contraceptives

1 reference

12 December 2020

Clinical and metabolic effects of a pill containing 30 mcg ethinylestradiol plus 75 mcg gestodene.

1 reference

12 December 2020

Pharmacokinetics of gestodene and ethinylestradiol in 14 women during three months of treatment with a new tri-step combination oral contraceptive: serum protein binding of gestodene and influence of treatment on free and total testosterone levels i

1 reference

12 December 2020

Effect of oral contraceptive use on the incidence of impaired glucose tolerance and diabetes mellitus

1 reference

12 December 2020

Relative bioavailability of ethinyl estradiol from two different oral contraceptive formulations after single oral administration to 18 women in an intraindividual cross-over design

1 reference

12 December 2020

Pharmacokinetics and serum protein binding of gestodene and 3-keto-desogestrel in women after single oral administration of two different contraceptive formulations

1 reference

12 December 2020

Metabolic changes during treatment with two different progestogens

1 reference

12 December 2020

Effects of low-dose estrogen oral contraceptives on weight, body composition, and fat distribution in young women.

1 reference

12 December 2020

Triphasic combination of ethinyl estradiol and gestodene. Long-term clinical trial.

1 reference

12 December 2020

Metabolic investigations with Femodene--an oral contraceptive containing gestodene and ethinyloestradiol

1 reference

12 December 2020

The effect on blood pressure of a monophasic oral contraceptive containing ethinylestradiol and gestodene

1 reference

12 December 2020

Pharmacokinetics and protein binding of gestodene under treatment with a low-dose combination oral contraceptive for three months

1 reference

12 December 2020

Concentration of Ethinyl Estradiol in the Serum of 31 Young Women following a Treatment Period of 3 Months with Two Low-Dose Oral Contraceptives in an Intraindividual Cross-Over Design

1 reference

12 December 2020

Systemic availability of levonorgestrel after single oral administration of a norgestimate-containing combination oral contraceptive to 12 young women

1 reference

12 December 2020

Gestoden, an innovative progestogen

1 reference

12 December 2020

Norgestrel and gestodene stimulate breast cancer cell growth through an oestrogen receptor mediated mechanism

1 reference

12 December 2020

Effects of monophasic low-dose oral contraceptives on fibrin formation and resolution in young women

1 reference

12 December 2020

The new era in oral contraception: pills containing gestodene, norgestimate, and desogestrel

1 reference

12 December 2020

Clinical experience with a modern low-dose oral contraceptive in almost 100,000 users

1 reference

12 December 2020

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation

1 reference

12 December 2020

Relative binding affinity of norgestimate and other progestins for human sex hormone-binding globulin

1 reference

12 December 2020

The rationale for lowering serum cholesterol levels in American children

1 reference

12 December 2020

Effects of two triphasic oral contraceptives containing ethinylestradiol plus levonorgestrel or gestodene on blood coagulation and fibrinolysis

1 reference

12 December 2020

Protein binding of active ingredients and comparison of serum ethinyl estradiol, sex hormone-binding globulin, corticosteroid-binding globulin, and cortisol levels in women using a combination of gestodene/ethinyl estradiol (Femovan) or a combinatio

1 reference

12 December 2020

Ultrasound evaluation of ovarian activity under oral contraceptives

1 reference

12 December 2020

New progestogens in oral contraception

1 reference

12 December 2020

The effects of levonorgestrel, desogestrel and gestodene on the pulsatile release of luteinizing hormone in oral contraceptive users.

1 reference

12 December 2020

Efficacy, cycle control and side-effects of two monophasic combination oral contraceptives: gestodene/ethinylestradiol and norgestimate/ethinylestradiol

1 reference

12 December 2020

The growth inhibition of human breast cancer cells by a novel synthetic progestin involves the induction of transforming growth factor beta

1 reference

12 December 2020

Inhibition of ovulation by low-dose monophasic contraceptive containing gestodene

1 reference

12 December 2020

Inhibition of oral contraceptive steroid-metabolizing enzymes by steroids and drugs

1 reference

12 December 2020

Medical aspects of oral contraceptive discontinuation

1 reference

12 December 2020

The suppression of ovarian function by the new oral contraceptive--Femodene

1 reference

12 December 2020

Characteristics of the new progestogens in combination oral contraceptives

1 reference

12 December 2020

A comparison of the effects of two triphasic oral contraceptives on haemostasis

1 reference

12 December 2020

Lipoprotein alterations from a triphasic oral contraceptive containing ethinyl estradiol and gestodene. A 12-month trial.

1 reference

12 December 2020

Evidence for a novel binding site for the synthetic progestogen, gestodene on oestrogen receptor in human malignant tissue

1 reference

12 December 2020

Clinical comparison of two low-dose oral contraceptives, Minulet and Mercilon, in women over 30 years of age.

1 reference

12 December 2020

The pharmacokinetics of ethynylestradiol in the presence and absence of gestodene and desogestrel

1 reference

12 December 2020

Cholesterol and coronary heart disease in women: an overview of primary and secondary prevention

1 reference

12 December 2020

Effects of progestins on the proliferation of estrogen-dependent human breast cancer cells under growth factor-defined conditions

1 reference

12 December 2020

Changes in haemostasis after stopping the combined contraceptive pill: implications for major surgery

1 reference

12 December 2020

Protein binding of the contraceptive steroids gestodene, 3-keto-desogestrel and ethinylestradiol in human serum

1 reference

12 December 2020

Clinical comparison of monophasic oral contraceptive preparations of gestodene/ethinyl estradiol and desogestrel/ethinyl estradiol. Latin American Oral Contraceptive Study Group

1 reference

12 December 2020

Effects of newer oral contraceptives on the inhibition of coagulation and fibrinolysis in relation to dosage and type of steroid

1 reference

12 December 2020

Safety and efficacy of a combined oral contraceptive: gestodene 75 micrograms plus ethinyl estradiol 30 micrograms in Mexican women

1 reference

12 December 2020

Oral contraceptives and myocardial infarction

1 reference

12 December 2020

Thromboembolism and the combined oral contraceptive pill

1 reference

12 December 2020

Inhibition of antipyrine metabolism by low-dose contraceptives with gestodene and desogestrel

1 reference

12 December 2020

Effect of four combined oral contraceptives on blood pressure in the pill-free interval

1 reference

12 December 2020

Clinical pharmacokinetics of contraceptive steroids. An update

1 reference

12 December 2020

Gestodene: a novel synthetic progestin--characterization of binding to receptor and serum proteins

1 reference

12 December 2020

Open prospective multicenter trial with a new monophasic contraceptive combination containing gestodene

1 reference

12 December 2020

Clinical and hormonal effects of two contraceptives: Correlation to serum concentrations of levonorgestrel and gestodene

1 reference

12 December 2020

A comparative metabolic study of two low-estrogen-dose oral contraceptives containing desogestrel or gestodene progestins.

1 reference

12 December 2020

Mechanism of action of oral contraceptives on carbohydrate metabolism at the cellular level

1 reference

12 December 2020

Evaluation of a new generation of oral contraceptives. The Advisory Board for the New Progestins

1 reference

12 December 2020

Characterization of the novel progestin gestodene by receptor binding studies and transactivation assays

1 reference

12 December 2020

Oral contraceptives and risk of breast cancer in women aged 20-54 years. Netherlands Oral Contraceptives and Breast Cancer Study Group

1 reference

12 December 2020

Carbohydrate metabolism studies after one year of using an oral contraceptive containing gestodene and ethinyl estradiol.

1 reference

12 December 2020

Pharmacokinetics of the contraceptive steroids levonorgestrel and gestodene after single and multiple oral administration to women

1 reference

12 December 2020

Gestodene: clinical experience with an innovative progestogen used in a combination oral contraceptive preparation

1 reference

12 December 2020

Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene

1 reference

12 December 2020

Contraception for women with diabetes: an update

1 reference

12 December 2020

Association of early-onset coronary heart disease in South Asian men with glucose intolerance and hyperinsulinemia

1 reference

12 December 2020

What do women use when they stop using the pill?

1 reference

12 December 2020

Clinical and metabolic effects of a triphasic pill containing gestodene

1 reference

12 December 2020

Comparison of two triphasic oral contraceptives containing either gestodene or norethindrone: a randomized, controlled trial

1 reference

12 December 2020

Combined oral contraceptives: risks and benefits

1 reference

12 December 2020

Development and application of a radioimmunoassay of the new progestagen gestodene.

1 reference

12 December 2020

A double-blind comparison of the efficacy and acceptability of Femodene and Microgynon-30

1 reference

12 December 2020

Single and multiple administration of a new triphasic oral contraceptive to women: pharmacokinetics of ethinyl estradiol and free and total testosterone levels in serum

1 reference

12 December 2020

Effect of seven low-dose combined oral contraceptive preparations on carbohydrate metabolism.

1 reference

12 December 2020

Serum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene

1 reference

12 December 2020

The selectivity of a new progestin

1 reference

12 December 2020

Pharmacokinetics of gestodene in 12 women who received a single oral dose of 0.075 mg gestodene and, after a wash-out phase, the same dose during one treatment cycle

1 reference

12 December 2020

Combined oral contraceptives: acceptability and effective use.

1 reference

12 December 2020

Oral contraceptives, clotting factors, and thrombosis

1 reference

12 December 2020

New progestins--clinical experiences: gestodene

1 reference

12 December 2020

Influence of modern low-dose oral contraceptives on hemostasis

1 reference

12 December 2020

Effects of seven low-dose combined oral contraceptives on sex hormone binding globulin, corticosteroid binding globulin, total and free testosterone

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of oral contraceptive steroids: factors influencing steroid metabolism

1 reference

12 December 2020

Lipids, lipoproteins, women and cardiovascular disease

1 reference

12 December 2020

Alterations in the serum levels of gestodene and SHBG during 12 cycles of treatment with 30 micrograms ethinylestradiol and 75 micrograms gestodene

1 reference

12 December 2020

The estrogenic activity of synthetic progestins used in oral contraceptives.

1 reference

12 December 2020

Group comparison of serum ethinyl estradiol, SHBG and CBG levels in 83 women using two low-dose combination oral contraceptives for three months

1 reference

12 December 2020

10.2165/00003495-199550020-00010

Identifiers

DOI

1 reference

PubMed ID

8521763

Dimensions Publication ID

24 September 2017

0 references

1 reference

PubMed ID

8521763