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Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis.
scientific article published on October 1996
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
review article
1 reference
stated in
Europe PubMed Central
title
Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
author
Han-Ming Shen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
author name string
C N Ong
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
language of work or name
English
0 references
publication date
1 October 1996
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
published in
Mutation Research
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
volume
366
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
page(s)
23-44
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
cites work
Geographic variation of p53 mutational profile in nonmalignant human liver
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Endogenous DNA damage as related to cancer and aging
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Evidence for membrane-mediated chromosomal damage by aflatoxin B1 in human lymphocytes
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7 January 2021
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ras oncogenes: their role in neoplasia
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Crossref
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7 January 2021
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Mutations in the Ha-ras proto-oncogene in spontaneous and chemically induced liver tumours of the CF1 mouse.
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7 January 2021
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Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences.
1 reference
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7 January 2021
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p53 protein accumulation in European hepatocellular carcinoma is not always dependent on p53 gene mutation
1 reference
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7 January 2021
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Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
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7 January 2021
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Risk assessment for aflatoxin: II. Implications of human epidemiology data
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7 January 2021
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Oxy-radicals and cancer
1 reference
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7 January 2021
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Analysis of the p53 tumor-suppressor gene in hepatocellular carcinomas from Britain
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Infrequent point mutations in codons 12 and 61 of ras oncogenes in human hepatocellular carcinomas
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Identification and partial characterization of new antigens from simian virus 40-transformed mouse cells
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Analysis ofras gene mutations in rainbow trout liver tumors initiated by aflatoxin B1
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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The expression of p53 antigen in primary malignant epithelial tumors of the liver: an immunohistochemical study
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
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Expression of mutant p53 protein in hepatocellular carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
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High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Shuttle-vector mutagenesis by aflatoxin B1 in human cells: effects of sequence context on the supF mutational spectrum.
1 reference
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Overexpression of p53 protein and Ki67 proliferative index in hepatocellular carcinoma: an immunohistochemical study on 109 Italian patients
1 reference
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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A new mutational hot-spot in the p53 gene in human hepatocellular carcinoma
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Absence of p53 mutation at codon 249 in duck hepatocellular carcinomas from the high incidence area of Qidong (China).
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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Mechanisms of aflatoxin carcinogenesis
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
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Activation of cellular oncogenes by chemical carcinogens in Syrian hamster embryo fibroblasts
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Crossref
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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inferred from DOI database lookup
The role of 8-hydroxyguanine in carcinogenesis
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Crossref
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Carcinogen-mediated oxidant formation and oxidative DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural alterations in c-myc and c-Ha-ras proto-oncogenes in human hepatocellular carcinoma
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a murine p53SER246 mutant equivalent to the human p53SER249 associated with hepatocellular carcinoma and aflatoxin exposure
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatitis B and alterations of the p53 tumor suppressor gene in hepatocellular carcinoma.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aflatoxin exposure in human populations: measurements and relationship to cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
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inferred from DOI database lookup
p53: at the crossroads of molecular carcinogenesis and risk assessment
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Crossref
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical implications of the p53 tumor-suppressor gene
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Crossref
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7 January 2021
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The mutation of codon 249 in the p53 gene is not specific in Japanese hepatocellular carcinoma
1 reference
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Crossref
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7 January 2021
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Hepatocellular carcinoma mutation
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Crossref
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7 January 2021
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p53 mutations in human cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutations and aflatoxin B1 exposure in hepatocellular carcinoma patients from Thailand
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of p53 Gene in Hepatocellular Carcinoma: Roles of Hepatitis B Virus and Aflatoxin Contamination in the Diet
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recent aflatoxin exposure and mutation at codon 249 of the human p53 gene: lack of association.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational hot spot in the p53 gene in human hepatocellular carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aflatoxin and p53 abnormality in duck hepatocellular carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA replication-blocking properties of adducts formed by aflatoxin B1-2,3-dichloride and aflatoxin B1-2,3-oxide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene: effects of sequence contexts on mutation spectra
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation at codon 249 of p53 gene in a human hepatoblastoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Salmonella typhimurium strain TA100 differentiates several classes of carcinogens and mutagens by base substitution specificity.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Enzymatic and non-enzymatic formation of free radicals from aflatoxin B1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic changes and histopathological grades in human hepatocellular carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T antigen is bound to a host protein in SY40-transformed cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of p53: a rare event in a large series of white patients with hepatocellular carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53 tumour suppressor gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrations of p53 gene in human hepatocellular carcinoma from China.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
p53 expression in patients with cirrhosis with and without hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Function and regulation of ras.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Covalent and noncovalent interactions of aflatoxin with defined deoxyribonucleic acid sequences
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli
1 reference
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https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunohistochemical detection of aberrant p53 expression in hepatocellular carcinoma: correlation with cell proliferative activity indices, including mitotic index and MIB-1 immunostaining
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression and point mutations of p53 tumor suppressor gene in hepatocellular carcinomas in Hong Kong Chinese people
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 gene mutations and 17p allelic deletions in hepatocellular carcinoma from Japan
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Point mutation, allelic loss and increased methylation of c-Ha-Ras gene in human hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 immunoreactivity in hepatocellular adenoma, focal nodular hyperplasia, cirrhosis and hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutations in nonmalignant human liver: fingerprints of aflatoxins?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 mutation in hepatocellular carcinoma after aflatoxin exposure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 codon 249ser mutations in hepatocellular carcinoma patients with low aflatoxin exposure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative analysis of p53 and c-myc expression and cell proliferation in human hepatocellular carcinomas--an enhanced immunohistochemical approach
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 in malignant and benign liver lesions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aflatoxin B1-induced lipid peroxidation in rat liver.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aflatoxin B1-induced 8-hydroxydeoxyguanosine formation in rat hepatic DNA.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Codon 249 mutation of the p53 gene is a rare event in hepatocellular carcinomas from ethnic Chinese in Singapore
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor-suppressor p53 gene in hepatitis C and B virus-associated human hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of the c-Ha-ras and c-myc genes in aflatoxin B1-induced hepatocellular carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of p53 mutations and various frequencies of Ki-ras exon 1 mutations in rat hepatic tumors induced by different carcinogens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinds of mutations induced by aflatoxin B1 in a shuttle vector replicating in human cells transiently expressing cytochrome P450IA2 cDNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low incidence of point mutation of c-Ki-ras and N-ras oncogenes in human hepatocellular carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 expression in hepatocellular carcinoma in a population in Singapore with endemic hepatitis B virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 codon 249ser hot-spot mutation in HBV-negative hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the covalent binding of aflatoxin B1-dichloride to cytosine in DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of heterozygosity and analysis of mutation of p53 in hepatocellular carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0165-1110%2896%2990005-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0165-1110(96)90005-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
PubMed publication ID
8921985
1 reference
stated in
Europe PubMed Central
PubMed publication ID
8921985
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8921985%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 October 2019
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