(Q40932895)

25 September 2017

title

L-arginine binding to nitric-oxide synthase. The role of H-bonds to the nonreactive guanidinium nitrogens (English)

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25 September 2017

Babu BR

1

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25 September 2017

Frey C

series ordinal

2

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25 September 2017

Griffith OW

series ordinal

3

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25 September 2017

language of work or name

English

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publication date

1 September 1999

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Journal of Biological Chemistry

25 September 2017

published in

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25 September 2017

volume

274

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25 September 2017

issue

36

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25 September 2017

page(s)

25218-25226

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Nitric oxide synthases: properties and catalytic mechanism

25 September 2017

cites work

1 reference

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Structure-function aspects in the nitric oxide synthases

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The nitric oxide synthase family of proteins

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Nitric oxide signaling in the central nervous system

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NG-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?

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Nitric oxide in the regulation of blood flow and arterial pressure

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The role of nitric oxide in inflammation and immunity

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Role of nitric oxide synthesis in macrophage antimicrobial activity

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Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

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Suppression of arthritis by an inhibitor of nitric oxide synthase

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Nitric oxide and arthritis

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Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

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Inhibition of constitutive and inducible nitric oxide synthase: potential selective inhibition

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Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy

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The availability of the acetyl derivatives of lysine for growth

21 January 2018

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Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide

21 January 2018

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Characterization of bovine endothelial nitric oxide synthase expressed in E. coli.

21 January 2018

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Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors

21 January 2018

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High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli

21 January 2018

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Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase.

21 January 2018

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Irreversible inactivation of macrophage and brain nitric oxide synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation

21 January 2018

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Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine

21 January 2018

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L-canavanine, an inhibitor of inducible nitric oxide synthase, improves venous return in endotoxemic rats.

21 January 2018

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Prokaryotic expression of the heme- and flavin-binding domains of rat neuronal nitric oxide synthase as distinct polypeptides: identification of the heme-binding proximal thiolate ligand as cysteine-415.

21 January 2018

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Optical difference spectrophotometry as a probe of rat brain nitric oxide synthase heme-substrate interaction

21 January 2018

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Spatial relationship between L-arginine and heme binding sites of endothelial nitric-oxide synthase.

21 January 2018

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Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

21 January 2018

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Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

21 January 2018

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

21 January 2018

1 reference

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NO synthase isozymes have distinct substrate binding sites

21 January 2018

1 reference

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Mutagenesis of acidic residues in the oxygenase domain of inducible nitric-oxide synthase identifies a glutamate involved in arginine binding.

21 January 2018

1 reference

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Mutation of Glu-361 in human endothelial nitric-oxide synthase selectively abolishes L-arginine binding without perturbing the behavior of heme and other redox centers

21 January 2018

1 reference

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Characterization by electron paramagnetic resonance of the interactions of L-arginine and L-thiocitrulline with the heme cofactor region of nitric oxide synthase

21 January 2018

1 reference

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Binding of intermediate, product, and substrate analogs to neuronal nitric oxide synthase: ferriheme is sensitive to ligand-specific effects in the L-arginine binding site

21 January 2018

1 reference

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Nitric oxide synthase inhibition in migraine

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.36.25218

1 reference

25 September 2017

1 reference