(Q40933351)

25 September 2017

title

Quantitative aspects of the selective killing of transformed cells by methotrexate in the presence of leucovorin (English)

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25 September 2017

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Chow M

1

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25 September 2017

Rubin H

series ordinal

2

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25 September 2017

language of work or name

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1 July 1999

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In Vitro Cellular & Developmental Biology - Animal

25 September 2017

published in

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25 September 2017

volume

35

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25 September 2017

issue

7

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25 September 2017

page(s)

394-402

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https://scigraph.springernature.com/pub.10.1007/s11626-999-0114-5

25 September 2017

exact match

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cites work

Random population-wide genetic damage induced in replicating cells treated with methotrexate

1 reference

https://api.crossref.org/works/10.1007%2FS11626-999-0114-5

Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11626-999-0114-5

A comparison of mutation induction at the tk and hprt loci in human lymphoblastoid cells; quantitative differences are due to an additional class of mutations at the autosomal tk locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11626-999-0114-5

Gamma-ray mutagenesis measurement in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11626-999-0114-5

Mammalian folylpoly-gamma-glutamate synthetase. 4. In vitro and in vivo metabolism of folates and analogues and regulation of folate homeostasis

21 January 2018

1 reference

12 December 2020

Relationship between x-ray exposure and malignant transformation in C3H 10T1/2 cells

1 reference

12 December 2020

Age-dependent induction of hepatic tumor regression by the tissue microenvironment after transplantation of neoplastically transformed rat liver epithelial cells into the liver

1 reference

12 December 2020

Evidence for the progressive and adaptive nature of spontaneous transformation in the NIH 3T3 cell line

1 reference

12 December 2020

Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates

1 reference

12 December 2020

Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells

1 reference

12 December 2020

Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division

1 reference

12 December 2020

The nature of mutants induced by ionising radiation in cultured hamster cells. III. Molecular characterization of HPRT-deficient mutants induced by gamma-rays or alpha-particles showing that the majority have deletions of all or part of the hprt gen

1 reference

12 December 2020

Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo

1 reference

12 December 2020

Role of methotrexate polyglutamylation and cellular energy metabolism in inhibition of methotrexate binding to dihydrofolate reductase by 5-formyltetrahydrofolate in Ehrlich ascites tumor cells in vitro

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12 December 2020

Accumulation of DNA strand breaks and methotrexate cytotoxicity

1 reference

12 December 2020

Optimization of high-dose methotrexate with leucovorin rescue therapy in the L1210 leukemia and sarcoma 180 murine tumor models

1 reference

12 December 2020

Heritable, population-wide damage to cells as the driving force of neoplastic transformation

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12 December 2020

In situ analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells

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12 December 2020

Lessons from hereditary colorectal cancer

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12 December 2020

Clonal analysis of the expression of multiple transformation phenotypes and tumorigenicity by morphologically transformed 10T1/2 cells.

1 reference

12 December 2020

Selective killing of preneoplastic and neoplastic cells by methotrexate with leucovorin

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12 December 2020

Effects of folinic acid on hepatoma cells containing methotrexate polyglutamates

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12 December 2020

Neoplastic development: paradoxical relation between impaired cell growth at low population density and excessive growth at high density

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12 December 2020

Resistance of resting 3T6 mouse fibroblasts to methotrexate cytotoxicity

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12 December 2020

Irreversibility of cellular aging and neoplastic transformation: a clonal analysis

1 reference

12 December 2020

Evidence for cellular aging in long-term confluent cultures: heritable impairment of proliferation, accumulation of age pigments and their loss in neoplastic transformation

1 reference

12 December 2020

The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides

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12 December 2020

Radiation-induced genomic instability: delayed mutagenic and cytogenetic effects of X rays and alpha particles.

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12 December 2020

Eradication Of Leukaemic Cells (L1210) by Methotrexate and Methotrexate Plus Citrovorum Factor

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12 December 2020

New approaches to cancer chemotherapy with methotrexate

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12 December 2020

Chromosome 11 aberrations in small colony L5178Y TK-/- mutants early in their clonal history

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12 December 2020

Role of the cellular oxidation-reduction state in methotrexate binding to dihydrofolate reductase and dissociation induced by reduced folates.

1 reference

12 December 2020

Kinetic correlates of methotrexate transport and therapeutic responsiveness in murine tumors

1 reference

12 December 2020

10.1007/S11626-999-0114-5

Identifiers

DOI

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Dimensions Publication ID

25 September 2017

1036991881

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