(Q40944251)

25 September 2017

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title

Development of retroviral vectors as safe, targeted gene delivery systems (English)

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25 September 2017

W H Günzburg

1

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PubMed ID

8740648

25 September 2017

B Salmons

series ordinal

2

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25 September 2017

1 April 1996

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Journal of Molecular Medicine

25 September 2017

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25 September 2017

74

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25 September 2017

4

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25 September 2017

171-182

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A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

25 September 2017

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12 December 2020

Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region

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12 December 2020

Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectors

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12 December 2020

In situ retroviral-mediated gene transfer for the treatment of brain tumors in rats

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12 December 2020

Type C retrovirus inactivation by human complement is determined by both the viral genome and the producer cell.

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12 December 2020

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12 December 2020

Retroviral vectors for persistent expression in vivo

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12 December 2020

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

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12 December 2020

The structure and function of retroviral long terminal repeats

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12 December 2020

Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells

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12 December 2020

Antibody-mediated binding of a murine ecotropic Moloney retroviral vector to human cells allows internalization but not the establishment of the proviral state.

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12 December 2020

Further characterization of the interaction between the C1q subcomponent of human C1 and the transmembrane envelope glycoprotein gp41 of HIV-1.

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12 December 2020

Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication

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12 December 2020

Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus

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12 December 2020

A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family

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12 December 2020

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production

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12 December 2020

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12 December 2020

High level expression and export of beta-glucuronidase from murine mucopolysaccharidosis VII cells corrected by a double-copy retrovirus vector.

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12 December 2020

Molecular biology of the human immunodeficiency virus type 1

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12 December 2020

Protection of retroviral vector particles in human blood through complement inhibition

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12 December 2020

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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12 December 2020

A family of retroviruses that utilize related phosphate transporters for cell entry

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12 December 2020

Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range

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12 December 2020

Human immunodeficiency virus vectors for inducible expression of foreign genes

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12 December 2020

Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cells

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12 December 2020

Genetic background affects integration frequency of ecotropic proviral sequences into the mouse germ line.

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12 December 2020

Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector

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12 December 2020

Transport of cationic amino acids by the mouse ecotropic retrovirus receptor.

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12 December 2020

Human serum lyses RNA tumour viruses

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12 December 2020

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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12 December 2020

Lack of correlation between basal expression levels and susceptibility to transcriptional shutdown among single-gene murine leukemia virus vector proviruses

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12 December 2020

A versatile and potentially general approach to the targeting of specific cell types by retroviruses: application to the infection of human cells by means of major histocompatibility complex class I and class II antigens by mouse ecotropic murine le

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12 December 2020

Pseudotypes of vesicular stomatitis virus with the coat of murine leukaemia and of avian myeloblastosis viruses

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12 December 2020

Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity

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12 December 2020

Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes.

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12 December 2020

Characterization of recombinant helper retroviruses from Moloney-based vectors in ecotropic and amphotropic packaging cell lines

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12 December 2020

In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy

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12 December 2020

A chimeric avian retrovirus containing the influenza virus hemagglutinin gene has an expanded host range

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12 December 2020

Packaging system for rapid production of murine leukemia virus vectors with variable tropism

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12 December 2020

Factors affecting long-term stability of Moloney murine leukemia virus-based vectors

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12 December 2020

Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.

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12 December 2020

High frequency germline acquisition of ecotropic MuLV proviruses in SWR/J-RF/J hybrid mice

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12 December 2020

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells

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12 December 2020

A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing

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12 December 2020

Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery

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12 December 2020

Pattern of expression of ecotropic murine leukemia virus in gonads of inoculated SWR/J mice

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12 December 2020

Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity.

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12 December 2020

Spontaneous germ-line ecotropic murine leukemia virus infection: implications for retroviral insertional mutagenesis and germ-line gene transfer.

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12 December 2020

Retroviral-mediated gene transfer

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12 December 2020

Tissue-specific targeting of retroviral vectors through ligand-receptor interactions

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12 December 2020

Analysis of the functional and host range-determining regions of the murine ectropic and amphotropic retrovirus envelope proteins

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12 December 2020

Retroviral vectors displaying functional antibody fragments

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12 December 2020

A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector system utilizing stable HIV-1 packaging cell lines

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12 December 2020

High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range

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12 December 2020

Targeting of retroviral vectors for gene therapy

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12 December 2020

A spleen necrosis virus-based retroviral vector which expresses two genes from a dicistronic mRNA

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12 December 2020

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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12 December 2020

Generation of high-titer pseudotyped retroviral vectors with very broad host range

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12 December 2020

New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors

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12 December 2020

Replication-defective chimeric helper proviruses and factors affecting generation of competent virus: expression of Moloney murine leukemia virus structural genes via the metallothionein promoter

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12 December 2020

Chemical modification of an ecotropic murine leukemia virus results in redirection of its target cell specificity

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12 December 2020

Factors affecting retroviral vector function and structural integrity

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12 December 2020

Identification of a cellular receptor for mouse mammary tumor virus and mapping of its gene to chromosome 16

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12 December 2020

Retroviral vector particles displaying the antigen-binding site of an antibody enable cell-type-specific gene transfer

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12 December 2020

Human T-cell leukaemia virus is not lysed by human serum

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12 December 2020

Analysis of retroviral packaging lines for generation of replication-competent virus

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12 December 2020

Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component.

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12 December 2020

Efficient gene expression in mammalian cells from a dicistronic transcriptional unit in an improved retroviral vector

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12 December 2020

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12 December 2020

Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter.

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12 December 2020

The AIDS-associated retrovirus is not sensitive to lysis or inactivation by human serum.

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12 December 2020

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

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12 December 2020

Retroviral vectors directed to predefined cell types for gene therapy.

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12 December 2020

Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors

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12 December 2020

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer

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12 December 2020

HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator

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12 December 2020

Construction and use of a safe and efficient amphotropic packaging cell line

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12 December 2020

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

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12 December 2020

Basis for receptor specificity of nonecotropic murine leukemia virus surface glycoprotein gp70SU

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12 December 2020

Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses

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12 December 2020

Formation of infectious hybrid virions with gibbon ape leukemia virus and human T-cell leukemia virus retroviral envelope glycoproteins and the gag and pol proteins of Moloney murine leukemia virus

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12 December 2020

Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes

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12 December 2020

Construction of retroviral vectors for targeted delivery and expression of therapeutic genes

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12 December 2020

Negative regulatory element in the mammary specific whey acidic protein promoter

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12 December 2020

The efficiency of cell targeting by recombinant retroviruses depends on the nature of the receptor and the composition of the artificial cell-virus linker

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12 December 2020

Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA.

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12 December 2020

A safe packaging line for gene transfer: separating viral genes on two different plasmids

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12 December 2020

Identifiers

DOI

10.1007/S001090050020

1 reference

25 September 2017

1 reference

PubMed ID

8740648