(Q40945823)

English

3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation

scientific article published on July 1999

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scholarly article

1 reference

Europe PubMed Central

25 September 2017

3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation (English)

1 reference

Europe PubMed Central

25 September 2017

1 reference

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author name string

S Y Jeong

1

1 reference

Europe PubMed Central

25 September 2017

S G Ahn

2

1 reference

Europe PubMed Central

25 September 2017

J H Lee

3

1 reference

Europe PubMed Central

25 September 2017

H S Kim

4

1 reference

Europe PubMed Central

25 September 2017

J W Kim

5

1 reference

Europe PubMed Central

25 September 2017

H Rhim

6

1 reference

Europe PubMed Central

25 September 2017

S W Jeong

7

1 reference

Europe PubMed Central

25 September 2017

I K Kim

8

1 reference

Europe PubMed Central

25 September 2017

language of work or name

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publication date

1 July 1999

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Europe PubMed Central

25 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

25 September 2017

274

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Europe PubMed Central

25 September 2017

18981-18988

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Europe PubMed Central

25 September 2017

27

1 reference

Europe PubMed Central

25 September 2017

Function and activation of NF-kappa B in the immune system

1 reference

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21 January 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

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21 January 2018

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

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21 January 2018

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

1 reference

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21 January 2018

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

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21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

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21 January 2018

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

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21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Inhibition of NF-kappa B by sodium salicylate and aspirin

1 reference

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21 January 2018

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

1 reference

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21 January 2018

Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B

1 reference

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21 January 2018

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

1 reference

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21 January 2018

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

1 reference

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21 January 2018

Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways

1 reference

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21 January 2018

Elevated cyclic AMP inhibits NF-kappaB-mediated transcription in human monocytic cells and endothelial cells.

1 reference

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21 January 2018

Perturbation of biochemical transmethylations by 3-deazaadenosine in vivo

1 reference

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21 January 2018

3-Deaza-adenosine and inhibition of HIV

1 reference

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21 January 2018

Anti-human immunodeficiency virus 1 (HIV-1) activities of 3-deazaadenosine analogs: increased potency against 3'-azido-3'-deoxythymidine-resistant HIV-1 strains

1 reference

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21 January 2018

Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: Evidence for a methylation reaction essential to cytolysis

1 reference

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21 January 2018

3-Deazaadenosine analogues inhibit the production of tumour necrosis factor-alpha in RAW264.7 cells stimulated with lipopolysaccharide

1 reference

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21 January 2018

Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

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21 January 2018

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

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21 January 2018

The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1 reference

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21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Autoregulation of I kappa B alpha activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Immunosuppressive effects of the S-adenosylhomocysteine hydrolase inhibitor, 3-deazaadenosine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Imidazo[4,5-c]pyridines (3-deazapurines) and their nucleosides as immunosuppressive and antiinflammatory agents

1 reference

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21 January 2018

Apoptosis of L1210 Leukemia Cells Induced by 3-Deazaadenosine Analogs: Differential Expression of c-myc, NF-Kappa B and Molecular Events

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Effects of 3-deazaadenosine on apoptosis-related gene transcripts in HL-60 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.27.18981

21 January 2018

Identifiers

10.1074/JBC.274.27.18981

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

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