(Q40946883)

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Calcilytic Ameliorates Abnormalities of Mutant Calcium-Sensing Receptor (CaSR) Knock-In Mice Mimicking Autosomal Dominant Hypocalcemia (ADH).

scientific article published on 12 May 2015

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scholarly article

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8 March 2020

Calcilytic Ameliorates Abnormalities of Mutant Calcium-Sensing Receptor (CaSR) Knock-In Mice Mimicking Autosomal Dominant Hypocalcemia (ADH) (English)

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8 March 2020

autosomal dominant hypocalcemia

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based on heuristic

inferred from title

10

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author name string

Bingzi Dong

1

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Itsuro Endo

2

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Yukiyo Ohnishi

3

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Takeshi Kondo

4

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Tomoka Hasegawa

5

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Norio Amizuka

6

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Hiroshi Kiyonari

7

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Go Shioi

8

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Masahiro Abe

9

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Toshio Matsumoto

11

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publication date

16 July 2015

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Journal of Bone and Mineral Research

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11

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1980-1993

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8 March 2020

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

1 reference

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The calcium-sensing receptor: a molecular perspective

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Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

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Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation

1 reference

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21 January 2018

Mutations in the Ca(2+)-sensing receptor gene cause autosomal dominant and sporadic hypoparathyroidism

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21 January 2018

A novel activating mutation (C129S) in the calcium-sensing receptor gene in a Japanese family with autosomal dominant hypocalcemia

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CASR gene activating mutations in two families with autosomal dominant hypocalcemia

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Functional activities of mutant calcium-sensing receptors determine clinical presentations in patients with autosomal dominant hypocalcemia

1 reference

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21 January 2018

A family of autosomal dominant hypocalcemia with a positive correlation between serum calcium and magnesium: identification of a novel gain of function mutation (Ser(820)Phe) in the calcium-sensing receptor

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21 January 2018

Activating mutations in the calcium-sensing receptor: genetic and clinical spectrum in 25 patients with autosomal dominant hypocalcaemia - a German survey

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Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites.

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21 January 2018

Functional characterization of calcium-sensing receptor mutations expressed in human embryonic kidney cells

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A familial syndrome of hypocalcemia with hypercalciuria due to mutations in the calcium-sensing receptor

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Therapy of hypoparathyroidism with intact parathyroid hormone

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21 January 2018

Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study

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21 January 2018

Long-term treatment of 12 children with chronic hypoparathyroidism: a randomized trial comparing synthetic human parathyroid hormone 1-34 versus calcitriol and calcium

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21 January 2018

Daily parathyroid hormone 1-34 replacement therapy for hypoparathyroidism induces marked changes in bone turnover and structure

1 reference

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21 January 2018

PTH(1-34) replacement therapy in a child with hypoparathyroidism caused by a sporadic calcium receptor mutation

1 reference

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21 January 2018

Calcium-sensing receptor 20 years later

1 reference

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21 January 2018

Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain

1 reference

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21 January 2018

Agonists and allosteric modulators of the calcium-sensing receptor and their therapeutic applications

1 reference

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21 January 2018

Positive and negative allosteric modulators promote biased signaling at the calcium-sensing receptor.

1 reference

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21 January 2018

JTT-305, an orally active calcium-sensing receptor antagonist, stimulates transient parathyroid hormone release and bone formation in ovariectomized rats.

1 reference

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21 January 2018

Cloning and characterization of kidney-specific promoter of human PTH/PTHrP receptor gene: absence of mutation in patients with pseudohypoparathyroidism type Ib.

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21 January 2018

Dynamic and quantitative Ca2+ measurements using improved cameleons

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21 January 2018

A novel ES cell line, TT2, with high germline-differentiating potency

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21 January 2018

A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission.

1 reference

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21 January 2018

Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.2551

21 January 2018

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.2551

21 January 2018

Standardized nomenclature, symbols, and units for bone histomorphometry: a 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.2551

21 January 2018

Structure and formation of the twisted plywood pattern of collagen fibrils in rat lamellar bone.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.2551

21 January 2018

Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.2551

21 January 2018

Autosomal dominant hypoparathyroidism with severe hypomagnesemia and hypocalcemia, successfully treated with recombinant PTH and continuous subcutaneous magnesium infusion

1 reference

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21 January 2018

Dynamic and structural properties of the skeleton in hypoparathyroidism

1 reference

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21 January 2018

Three dimensional cancellous bone structure in hypoparathyroidism

1 reference

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21 January 2018

PTH(1-84) administration reverses abnormal bone-remodeling dynamics and structure in hypoparathyroidism

1 reference

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21 January 2018

Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice

1 reference

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21 January 2018

Loss-of-function and gain-of-function mutations of calcium-sensing receptor: functional analysis and the effect of allosteric modulators NPS R-568 and NPS 2143.

1 reference

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21 January 2018

Mutations affecting G-protein subunit α11 in hypercalcemia and hypocalcemia

1 reference

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21 January 2018

Autosomal dominant hypoparathyroidism caused by germline mutation in GNA11: phenotypic and molecular characterization

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Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism

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Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.

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Mutational analysis of the adaptor protein 2 sigma subunit (AP2S1) gene: search for autosomal dominant hypocalcemia type 3 (ADH3).

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Analysis of AP2S1, a calcium-sensing receptor regulator, in familial and sporadic isolated hypoparathyroidism.

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Identifiers

10.1002/JBMR.2551

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8 March 2020

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