(Q40947024)

25 September 2017

title

Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1). (English)

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25 September 2017

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Gong M

1

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25 September 2017

Cowan KH

series ordinal

2

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25 September 2017

Gudas J

series ordinal

3

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25 September 2017

Moscow JA

series ordinal

4

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25 September 2017

language of work or name

English

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publication date

1 June 1999

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25 September 2017

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25 September 2017

volume

233

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25 September 2017

issue

1-2

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25 September 2017

page(s)

21-31

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Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

25 September 2017

cites work

1 reference

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7 January 2021

Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line.

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Resistance to tomudex (ZD1694): multifactorial in human breast and colon carcinoma cell lines

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7 January 2021

Detective transport of amethopterin (methotrexate) as a mechanism of resistance to the antimetabolite in L5178Y leukemic cells

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7 January 2021

Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate

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7 January 2021

Nuclear posttranscriptional processing of thymidine kinase mRNA at the onset of DNA synthesis

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Drug-resistant breast cancer cells frequently retain expression of a functional wild-type p53 protein.

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7 January 2021

Transport of methotrexate in L1210 cells: effect of ions on the rate and extent of uptake

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7 January 2021

Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis

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7 January 2021

Multiple regulatory steps control histone mRNA concentrations

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7 January 2021

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

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7 January 2021

Methotrexate transport and resistance.

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7 January 2021

Reduced folate carrier gene (RFC1) expression and anti-folate resistance in transfected and non-selected cell lines

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7 January 2021

Molecular cloning of the human placental folate transporter

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7 January 2021

Inappropriate transcription from the 5' end of the murine dihydrofolate reductase gene masks transcriptional regulation

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7 January 2021

Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5' end heterogeneity

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7 January 2021

Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake

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7 January 2021

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

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7 January 2021

Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons

1 reference

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7 January 2021

A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate

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7 January 2021

10.1016/S0378-1119(99)00166-3

Identifiers

DOI

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25 September 2017

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