(Q40947864)

25 September 2017

1 reference

title

Mechanotransduction and the functional response of bone to mechanical strain (English)

1 reference

25 September 2017

1 reference

R L Duncan

1

1 reference

25 September 2017

C H Turner

series ordinal

2

1 reference

25 September 2017

language of work or name

English

0 references

publication date

1 November 1995

1 reference

Calcified Tissue International

25 September 2017

1 reference

25 September 2017

57

1 reference

25 September 2017

344-358

1 reference

25 September 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1007/bf00302070

25 September 2017

0 references

cites work

Increased intracortical remodeling following fatigue damage

1 reference

12 December 2020

Inhibitors of microtubule assembly enhance beta-adrenergic and prostaglandin E1-stimulated cyclic AMP accumulation in S49 lymphoma cells

1 reference

12 December 2020

Bone remodeling in response to in vivo fatigue microdamage

1 reference

12 December 2020

Electromechanical potentials in cortical bone--II. Experimental analysis.

1 reference

12 December 2020

Prediction of bone adaptation using damage accumulation

1 reference

12 December 2020

α-Actinin: a direct link between actin and integrins

1 reference

12 December 2020

Mechanotransduction across the cell surface and through the cytoskeleton

1 reference

12 December 2020

Prostaglandin E2 enhances cortical bone mass and activates intracortical bone remodeling in intact and ovariectomized female rats

1 reference

12 December 2020

Preliminary in situ identification of estrogen target cells in bone.

1 reference

12 December 2020

Integrating with integrins

1 reference

12 December 2020

Actin filaments regulate epithelial Na+ channel activity

1 reference

12 December 2020

Cartilage response to mechanical force in high-density chondrocyte cultures

1 reference

12 December 2020

The role of calcium in the inhibition of cAMP accumulation in epiphyseal cartilage cells exposed to physiological pressure

1 reference

12 December 2020

Spaceflight results in formation of defective bone.

1 reference

12 December 2020

Hemodynamics and vascular endothelial biology.

1 reference

12 December 2020

Mechanical stresses and endochondral ossification in the chondroepiphysis

1 reference

12 December 2020

A determinant of bone architecture. The minimum effective strain.

1 reference

12 December 2020

Bone strain: a determinant of gait and speed?

1 reference

12 December 2020

Prevention of postmenopausal osteoporosis. A comparative study of exercise, calcium supplementation, and hormone-replacement therapy

1 reference

12 December 2020

Biochemical signal transduction of mechanical strain in osteoblast-like cells

1 reference

12 December 2020

A comparative analysis of streaming potentials in vivo and in vitro

1 reference

12 December 2020

Prostaglandin E2 stimulates DNA synthesis by a cyclic AMP-independent pathway in osteoblastic clone MC3T3-E1 cells

1 reference

12 December 2020

Peripheral control of movement

1 reference

12 December 2020

Increased trabecular bone mass in rats treated with human synthetic parathyroid hormone

1 reference

12 December 2020

Dual elevation of cyclic AMP and inositol phosphates in response to mechanical deformation of murine osteoblasts

1 reference

12 December 2020

Local stimulation of new bone formation by prostaglandin E1: quantitative histomorphometry and comparison of delivery by minipumps and controlled-release pellets

1 reference

12 December 2020

Mechanical stretching increases the number of cultured bone cells synthesizing DNA and alters their pattern of protein synthesis

1 reference

12 December 2020

The role of mechanical loading histories in the development of diarthrodial joints

1 reference

12 December 2020

Exogenous prostacyclin, but not prostaglandin E2, produces similar responses in both G6PD activity and RNA production as mechanical loading, and increases IGF-II release, in adult cancellous bone in culture

1 reference

12 December 2020

A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses

1 reference

12 December 2020

Morphological study of intercellular junctions during osteocyte differentiation

1 reference

12 December 2020

Bone mass and exercise

1 reference

12 December 2020

Effects of 1-week head-down tilt bed rest on bone formation and the calcium endocrine system

1 reference

12 December 2020

Skeletal changes during space flight

1 reference

12 December 2020

Mechanical forces and their second messengers in stimulating cell growth in vitro

1 reference

12 December 2020

Propagation of a calcium pulse between osteoblastic cells

1 reference

12 December 2020

1 reference

12 December 2020

A noninvasive, in vivo model for studying strain adaptive bone modeling

1 reference

12 December 2020

Parathyroid hormone promotes the disassembly of cytoskeletal actin and myosin in cultured osteoblastic cells: Mediation by cyclic AMP

1 reference

12 December 2020

Aging changes mechanical loading thresholds for bone formation in rats

1 reference

12 December 2020

Recognition of osteopontin and related peptides by an alpha v beta 3 integrin stimulates immediate cell signals in osteoclasts

1 reference

12 December 2020

Prostaglandin E2 adds bone to a cancellous bone site with a closed growth plate and low bone turnover in ovariectomized rats

1 reference

12 December 2020

Bone curvature: Sacrificing strength for load predictability?

1 reference

12 December 2020

Electromechanical potentials in cortical bone--I. A continuum approach

1 reference

12 December 2020

Protein kinase C mediates flow-induced prostaglandin E2 production in osteoblasts

1 reference

12 December 2020

Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation

1 reference

12 December 2020

Biomechanics of mammalian terrestrial locomotion

1 reference

12 December 2020

Characterization of osteogenic response to mechanical stimulation in cancellous bone of rat caudal vertebrae

1 reference

12 December 2020

In Vitro studies of the effect of intermittent compressive forces on cartilage cell proliferation

1 reference

12 December 2020

Osteoblasts increase their rate of division and align in response to cyclic, mechanical tension in vitro

1 reference

12 December 2020

Increased 3H-uridine levels in osteocytes following a single short period of dynamic bone loading in vivo

1 reference

12 December 2020

Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?

1 reference

12 December 2020

Oscillatory and step response electromechanical phenomena in human and bovine bone

1 reference

12 December 2020

Adaptation of cancellous bone to overloading in the adult rat: a single photon absorptiometry and histomorphometry study

1 reference

12 December 2020

Modulation of osteogenesis in fetal bone rudiments by mechanical stress in vitro

1 reference

12 December 2020

Homeostatic control of bone structure: an application of feedback theory

1 reference

12 December 2020

Mechanical loading thresholds for lamellar and woven bone formation

1 reference

12 December 2020

Mechanical transduction in biological systems

1 reference

12 December 2020

Bone matrix RGD glycoproteins: immunolocalization and interaction with human primary osteoblastic bone cells in vitro

1 reference

12 December 2020

Effect of parathyroid hormone and forskolin on cytoskeletal protein synthesis in cultured mouse osteoblastic cells

1 reference

12 December 2020

Biochemical effect of mechanical stress on cultured bone cells

1 reference

12 December 2020

Static vs dynamic loads as an influence on bone remodelling

1 reference

12 December 2020

Modulation of osteoblast function by prostaglandins

1 reference

12 December 2020

The reversibility of disuse osteoporosis. Studies of bone density, bone formation, and cell proliferation in bone tissue

1 reference

12 December 2020

Circulating levels of insulin-like growth factor-I and -II, and IGF-binding protein-3 in inflammation and after parathyroid hormone infusion

1 reference

12 December 2020

Skeletal structural adaptations to mechanical usage (SATMU): 2. Redefining Wolff's law: the remodeling problem

1 reference

12 December 2020

Stimulation of trabecular bone formation by insulin-like growth factor I in adult ovariectomized rats

1 reference

12 December 2020

Biochemical pathways involved in the translation of physical stimulus into biological message

1 reference

12 December 2020

Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape

1 reference

12 December 2020

Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow

1 reference

12 December 2020

Effects of a 1-wk spaceflight on morphological and mechanical properties of growing bone

1 reference

12 December 2020

The transduction of mechanical force into biochemical events in bone cells may involve activation of phospholipase A2

1 reference

12 December 2020

Bone Cells in Culture: Morphologic Transformation by Hormones

1 reference

12 December 2020

Increase of whole-body calcium and skeletal mass in normal and osteoporotic adult rats treated with parathyroid hormone

1 reference

12 December 2020

Regulation of bone formation by applied dynamic loads

1 reference

12 December 2020

Effect of flow on prostaglandin E2 and inositol trisphosphate levels in osteoblasts

1 reference

12 December 2020

Modulation of integrins expression during human osteoblasts "in vitro" differentiation

1 reference

12 December 2020

Mechanoreception by the endothelium: mediators and mechanisms of pressure- and flow-induced vascular responses

1 reference

12 December 2020

Cell spreading on extracellular matrix proteins induces tyrosine phosphorylation of tensin

1 reference

12 December 2020

Prostaglandin E2 restores cancellous bone to immobilized limb and adds bone to overloaded limb in right hindlimb immobilization rats

1 reference

12 December 2020

Verapamil decreases cyclic load-induced calcium incorporation in ROS 17/2.8 osteosarcoma cell cultures

1 reference

12 December 2020

Bone growth and calcium balance during simulated weightlessness in the rat.

1 reference

12 December 2020

Insulin-like growth factor I has independent effects on bone matrix formation and cell replication

1 reference

12 December 2020

Haemodynamic shear stress activates a K+ current in vascular endothelial cells.

1 reference

12 December 2020

Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium

1 reference

12 December 2020

The response of rat tibiae to incremental bouts of mechanical loading: a quantum concept for bone formation

1 reference

12 December 2020

Stiffening of the femoral head due to inter-trabecular fluid and intraosseous pressure.

1 reference

12 December 2020

Bone loss in response to long-term immobilisation

1 reference

12 December 2020

Induction of bone formation in rat tail vertebrae by mechanical loading

1 reference

12 December 2020

Parathyroid hormone activation of stretch-activated cation channels in osteosarcoma cells (UMR-106.01)

1 reference

12 December 2020

Increase in femoral bone density in young women following high-impact exercise

1 reference

12 December 2020

Prostaglandin E2 increased rat cortical bone mass when administered immediately following ovariectomy

1 reference

12 December 2020

Synthetic peptide containing Arg-Gly-Asp inhibits bone formation and resorption in a mineralizing organ culture system of fetal rat parietal bones

1 reference

12 December 2020

Osteocalcin as an indicator of bone metabolism during spaceflight

1 reference

12 December 2020

The inositol phosphate pathway as a mediator in the proliferative response of rat calvarial bone cells to cyclical biaxial mechanical strain

1 reference

12 December 2020

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton.

1 reference

12 December 2020

Prostaglandin E2 Stimulates Preosteoblast Replication: An Autoradiographic Study in Cultured Fetal Rat Calvariae

1 reference

12 December 2020

Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix

1 reference

12 December 2020

Voltage-activated ionic channels and conductances in embryonic chick osteoblast cultures

1 reference

12 December 2020

Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation

1 reference

12 December 2020

Cyclic AMP and Cyclic GMP: Mediators of the Mechanical Effects on Bone Remodeling

1 reference

12 December 2020

Musculoskeletal ontogeny, phylogeny, and functional adaptation

1 reference

12 December 2020

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins

1 reference

12 December 2020

Multiple forms of mechanosensitive ion channels in osteoblast-like cells

1 reference

12 December 2020

Inductive effects of prostaglandins on alkaline phosphatase in osteoblastic cells, clone MC3T3-E1

1 reference

12 December 2020

A hypothetical mechanism for the stimulation of osteonal remodelling by fatigue damage

1 reference

12 December 2020

Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells

1 reference

12 December 2020

Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells

1 reference

12 December 2020

Early loading-related changes in the activity of glucose 6-phosphate dehydrogenase and alkaline phosphatase in osteocytes and periosteal osteoblasts in rat fibulae in vivo

1 reference

12 December 2020

1 reference

12 December 2020

An approach for time-dependent bone modeling and remodeling--theoretical development

1 reference

12 December 2020

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown

1 reference

12 December 2020

Bone marrow cells are targets for the anabolic actions of prostaglandin E2 on bone: induction of a transition from nonadherent to adherent osteoblast precursors

1 reference

12 December 2020

Effect of spaceflight on periosteal bone formation in rats

1 reference

12 December 2020

Inhibition of Bone Formation During Space Flight

1 reference

12 December 2020

Tensile forces enhance prostaglandin E synthesis in osteoblastic cells grown on collagen ribbons

1 reference

12 December 2020

The effects of prostaglandin E2 on DNA and collagen synthesis in osteoblasts in vitro

1 reference

12 December 2020

Prostaglandin E2 stimulates collagen and non-collagen protein synthesis and prolyl hydroxylase activity in osteoblastic clone MC3T3-E1 cells

1 reference

12 December 2020

Increased bone growth by local prostaglandin E2 in rats

1 reference

12 December 2020

What role does the osteocyte network play in bone adaptation?

1 reference

12 December 2020

Microfilament modification by dihydrocytochalasin B causes retinoic acid-modulated chondrocytes to reexpress the differentiated collagen phenotype without a change in shape

1 reference

12 December 2020

Parathyroid and Thyroid Hormones in the Development of Immobilization Osteoporosis

1 reference

12 December 2020

Modulation of osteoclast differentiation

1 reference

12 December 2020

The effect of strain on bone cell prostaglandin E2 release: a new experimental method

1 reference

12 December 2020

Adaptation of diaphyseal structure with aging and increased mechanical usage in the adult rat: a histomorphometrical and biomechanical study

1 reference

12 December 2020

1 reference

12 December 2020

Mechanically adaptive bone remodelling

1 reference

12 December 2020

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

1 reference

12 December 2020

Voltage-activated and stretch-activated Ba2+ conducting channels in an osteoblast-like cell line (UMR 106).

1 reference

12 December 2020

Differentiation of canalicular cell processes in bone cells by basement membrane matrix components: regulation by discrete domains of laminin

1 reference

12 December 2020

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

1 reference

12 December 2020

Functional adaptation of bone to increased stress. An experimental study

1 reference

12 December 2020

Quantitative studies of endothelial cell adhesion. Directional remodeling of focal adhesion sites in response to flow forces

1 reference

12 December 2020

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape

1 reference

12 December 2020

Second messengers: regulators of mechanically-induced tissue remodelling

1 reference

12 December 2020

Alterations in chondrocyte cytoskeletal architecture during phenotypic modulation by retinoic acid and dihydrocytochalasin B-induced reexpression

1 reference

12 December 2020

Regulation of bone mass by mechanical strain magnitude

1 reference

12 December 2020

Suppression of the osteogenic response in the aging skeleton

1 reference

12 December 2020

Parathyroid hormone stimulates the bone apposition rate independently of its resorptive action: differential effects of intermittent and continuous administration

1 reference

12 December 2020

Reversibility of nontraumatic disuse osteoporosis during its active phase

1 reference

12 December 2020

Effects of weightlessness on bone mass and osteoclast number in pregnant rats after a five-day spaceflight (COSMOS 1514)

1 reference

12 December 2020

Flow effects on prostacyclin production by cultured human endothelial cells

1 reference

12 December 2020

Cytochalasin B enhances hormone and cholera toxin-stimulated cyclic AMP accumulation in S49 lymphoma cells

1 reference

12 December 2020

Fluid movement in bone: Theoretical and empirical

1 reference

12 December 2020

The incidence and size of gap junctions between the bone cells in rat calvaria

1 reference

12 December 2020

Control of intracellular pH and growth by fibronectin in capillary endothelial cells

1 reference

12 December 2020

Bone remodelling induced by physical stress is prostaglandin E2 mediated

1 reference

12 December 2020

A cumulative damage model for bone fracture.

1 reference

12 December 2020

A primary role for microfilaments, but not microtubules, in hormone-induced cytoplasmic retraction

1 reference

12 December 2020

Soluble alpha v beta 3-integrin ligands raise [Ca2+]i in rat osteoclasts and mouse-derived osteoclast-like cells

1 reference

12 December 2020

Bone Deformation Recorded in vivo from Strain Gauges Attached to the Human Tibial Shaft

1 reference

12 December 2020

The role of prostaglandins in bone in vivo

1 reference

12 December 2020

Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle

1 reference

12 December 2020

Bone response to alternate-day mechanical loading of the rat tibia

1 reference

12 December 2020

Prostaglandin E2 prevents disuse-induced cortical bone loss

1 reference

12 December 2020

Limb mechanics as a function of speed and gait: a study of functional strains in the radius and tibia of horse and dog

1 reference

12 December 2020

Cell adhesion in morphogenesis

1 reference

12 December 2020

From bone lining cell to osteocyte?an SEM study

1 reference

12 December 2020

The effect of low-frequency electrical fields on osteogenesis

1 reference

12 December 2020

Influence of the long-term, continuous bending on the bone. An experimental study on the tibia of the rabbit

1 reference

12 December 2020

Measurement of osteocytes per unit volume and volume components of osteocytes and canaliculae in man

1 reference

12 December 2020

Mechanotransduction in bone: do bone cells act as sensors of fluid flow?

1 reference

12 December 2020

Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation

1 reference

12 December 2020

Mechanoelectrical transduction by hair cells

1 reference

12 December 2020

Function follows form: generation of intracellular signals by cell deformation

1 reference

12 December 2020

Effects of prostaglandin E2 on production of new cancellous bone in the axial skeleton of ovariectomized rats

1 reference

12 December 2020

Increased trabecular bone density due to bone-loading exercises in postmenopausal osteoporotic women

1 reference

12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

12 December 2020

Adaptation of cancellous bone to aging and immobilization in growing rats

1 reference

12 December 2020

Skeletal change in response to altered strain environments: is woven bone a response to elevated strain?

1 reference

12 December 2020

Mechanosensitive ion channels.

1 reference

12 December 2020

Physical Exercise as Prophylaxis against Involutional Vertebral Bone Loss: A Controlled Trial

1 reference

12 December 2020

Reaction of bone to mechanical stimuli. 2. Periosteal and endosteal reaction of tibial diaphysis in rabbit to intermittent loading

1 reference

12 December 2020

Evidence for different sources of stress-generated potentials in wet and dry bone.

1 reference

12 December 2020

Parathyroid hormone stimulates release of insulin-like growth factor-I (IGF-I) and IGF-II from neonatal mouse calvaria in organ culture

1 reference

12 December 2020

Parathyroid hormone (1-34) and (1-84) stimulate cortical bone formation both from periosteum and endosteum

1 reference

12 December 2020

Skeletal structural adaptations to mechanical usage (SATMU): 1. Redefining Wolff's law: the bone modeling problem

1 reference

12 December 2020

Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures

1 reference

12 December 2020

Regulation of expression of the cell adhesion receptors, integrins, by recombinant human interleukin-1 beta in human osteosarcoma cells: inhibition of cell proliferation and stimulation of alkaline phosphatase activity

1 reference

12 December 2020

Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone

1 reference

12 December 2020

Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production

1 reference

12 December 2020

Chronic, intermittent loading alters mechanosensitive channel characteristics in osteoblast-like cells

1 reference

12 December 2020

Bone "mass" and the "mechanostat": a proposal.

1 reference

12 December 2020

Reaction of bone to mechanical stimuli. 1. Continuous and intermittent loading of tibia in rabbit

1 reference

12 December 2020

Low-amplitude, low-frequency electric field-stimulated bone cell proliferation may in part be mediated by increased IGF-II release

1 reference

12 December 2020

The influence of strain rate on adaptive bone remodelling

1 reference

12 December 2020

Functional adaptation of bone in response to sinusoidally varying controlled compressive loading of the ovine metacarpus

1 reference

12 December 2020

Bone resorption and mineral excretion in rats during spaceflight

1 reference

12 December 2020

Morphological evidence of gap junctions between bone cells

1 reference

12 December 2020

Quantum concept of bone remodeling and turnover: Implications for the pathogenesis of osteoporosis

1 reference

12 December 2020

Prostaglandin E2 prevents ovariectomy-induced cancellous bone loss in rats

1 reference

12 December 2020

Bone maturation in rats flown on the Spacelab-3 mission

1 reference

12 December 2020

Cellular responses to mechanical loading in vitro

1 reference

12 December 2020

Anabolic effects of parathyroid hormone on cortical bone in ovariectomized rats

1 reference

12 December 2020

Noninvasive loading of the rat ulna in vivo induces a strain-related modeling response uncomplicated by trauma or periostal pressure

1 reference

12 December 2020

Switching from differentiation to growth in hepatocytes: control by extracellular matrix

1 reference

12 December 2020

Response of cultured endothelial cells to mechanical stimulation

1 reference

12 December 2020

Effect of a continuously applied compressive pressure on mouse osteoblast-like cells (MC3T3-E1) in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00302070

1 reference

Dimensions Publication ID

25 September 2017

0 references

1 reference