(Q40949581)

English

Differential signaling by alternative HGF isoforms through c-Met: activation of both MAP kinase and PI 3-kinase pathways is insufficient for mitogenesis

scientific article published on June 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Differential signaling by alternative HGF isoforms through c-Met: activation of both MAP kinase and PI 3-kinase pathways is insufficient for mitogenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Donald P. Bottaro

5

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

author name string

Day RM

1

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Cioce V

2

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Breckenridge D

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Castagnino P

4

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

language of work or name

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publication date

1 June 1999

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

3399-3406

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1202683

0 references

Pathways in which growth factors and oncogenes interact in epithelial cell mitogenic signal transduction

1 reference

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Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

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Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

1 reference

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Hepatocyte growth factor (HGF)/NK1 is a naturally occurring HGF/scatter factor variant with partial agonist/antagonist activity

1 reference

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

1 reference

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Oncoprotein networks

1 reference

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Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists

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Functional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptors

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Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

1 reference

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Transformation of mammalian cells by constitutively active MAP kinase kinase

1 reference

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Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration

1 reference

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Heparin modulates the receptor-binding and mitogenic activity of hepatocyte growth factor on hepatocytes

1 reference

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Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

1 reference

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Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells

1 reference

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A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1 reference

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Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

1 reference

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Phosphatidylinositol 3-kinase activity is required for hepatocyte growth factor-induced mitogenic signals in epithelial cells

1 reference

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Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

1 reference

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7 January 2021

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Activation of the JNK pathway is essential for transformation by the Met oncogene

1 reference

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7 January 2021

based on heuristic

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Differential requirement of Grb2 and PI3-kinase in HGF/SF-induced cell motility and tubulogenesis

1 reference

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7 January 2021

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Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202683

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Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

1 reference

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Heparin binding and oligomerization of hepatocyte growth factor/scatter factor isoforms. Heparan sulfate glycosaminoglycan requirement for Met binding and signaling

1 reference

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Scatter factor/hepatocyte growth factor is essential for liver development

1 reference

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7 January 2021

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Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.

1 reference

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Mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways are not sufficient for insulin-like growth factor I-induced mitogenesis and tumorigenesis

1 reference

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Functional and biophysical characterization of recombinant human hepatocyte growth factor isoforms produced in Escherichia coli

1 reference

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Growth factors in the extracellular matrix

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Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

1 reference

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The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase

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The alpha PDGFR tyrosine kinase mediates locomotion of two different cell types through chemotaxis and chemokinesis

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Role of PI 3-kinase in mitogenesis

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

1 reference

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Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activity

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Identifiers

10.1038/SJ.ONC.1202683

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

ResearchGate publication ID

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