(Q40953591)

English

Target deletion of the bifunctional type 12 17β-hydroxysteroid dehydrogenase in mice results in reduction of androgen and estrogen levels in heterozygotes and embryonic lethality in homozygotes

scientific article published on August 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Target deletion of the bifunctional type 12 17β-hydroxysteroid dehydrogenase in mice results in reduction of androgen and estrogen levels in heterozygotes and embryonic lethality in homozygotes (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

author name string

Véronique Bellemare

1

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Daniel Phaneuf

2

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Van Luu-The

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

publication date

1 August 2010

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Hormone Molecular Biology and Clinical Investigation

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

311-318

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Characterization of type 12 17beta-hydroxysteroid dehydrogenase, an isoform of type 3 17beta-hydroxysteroid dehydrogenase responsible for estradiol formation in women

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

The intracrine sex steroid biosynthesis pathways

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Hydroxysteroid dehydrogenases: ancient and modern regulators of adrenal and sex steroid action.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Steroid receptor phylogeny and vertebrate origins

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Evolutionary genomics of nuclear receptors: from twenty-five ancestral genes to derived endocrine systems

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

LET-767 is required for the production of branched chain and long chain fatty acids in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Caenorhabditis elegans LET-767 is able to metabolize androgens and estrogens and likely shares common ancestor with human types 3 and 12 17beta-hydroxysteroid dehydrogenases

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Evolution of adrenal and sex steroid action in vertebrates: a ligand-based mechanism for complexity.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Complete amino acid sequence of human placental 17 beta-hydroxysteroid dehydrogenase deduced from cDNA.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Characterization of cDNAs for human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17: evidence of two mRNA species with distinct 5'-termini in human placenta

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Expression cloning of a novel estrogenic mouse 17 beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1)

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Specific estradiol biosynthetic pathway in choriocarcinoma (JEG-3) cell line

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Estradiol and estrone C-16 derivatives as inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: blocking of ER+ breast cancer cell proliferation induced by estrone

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Role for ELOVL3 and fatty acid chain length in development of hair and skin function

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Mouse Elovl-6 promoter is an SREBP target.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Differential estrogenic 17beta-hydroxysteroid dehydrogenase activity and type 12 17beta-hydroxysteroid dehydrogenase expression levels in preadipocytes and differentiated adipocytes

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Differential androgen and estrogen substrates specificity in the mouse and primates type 12 17beta-hydroxysteroid dehydrogenase

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Improved real-time RT-PCR method for high-throughput measurements using second derivative calculation and double correction.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Sex- and age-related response to aromatase deficiency in bone

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Male pseudohermaphroditism caused by mutations of testicular 17 beta-hydroxysteroid dehydrogenase 3

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Effect of testosterone and estradiol in a man with aromatase deficiency

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Effect of intravaginal dehydroepiandrosterone (Prasterone) on libido and sexual dysfunction in postmenopausal women.

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Intravaginal dehydroepiandrosterone (Prasterone), a physiological and highly efficient treatment of vaginal atrophy

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Tissue- and gender-specific mRNA expression of UDP-glucuronosyltransferases (UGTs) in mice

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

17Beta-hydroxysteroid dehydrogenase type 12 in human breast carcinoma: a prognostic factor via potential regulation of fatty acid synthesis

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Congenital adrenal hyperplasia due to point mutations in the type II 3 beta-hydroxysteroid dehydrogenase gene

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Hydroxysteroid (17{beta}) dehydrogenase 12 is essential for mouse organogenesis and embryonic survival

1 reference

https://api.crossref.org/works/10.1515%2FHMBCI.2010.036

21 January 2018

Identifiers

10.1515/HMBCI.2010.036

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

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