(Q40954976)

25 September 2017

GDNF: a novel factor with therapeutic potential for neurodegenerative disorders (English)

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25 September 2017

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Walton KM

1

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25 September 2017

1 February 1999

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25 September 2017

Molecular Neurobiology

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25 September 2017

19

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25 September 2017

1

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25 September 2017

43-59

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https://scigraph.springernature.com/pub.10.1007/bf02741377

25 September 2017

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cites work

Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02741377

GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02741377

Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. One-year follow-up of first clinical trial

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02741377

Developmental and denervation changes in c-ret proto-oncogene expression in chick motoneurons.

21 January 2018

1 reference

12 December 2020

GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo

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12 December 2020

Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

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12 December 2020

The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments

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12 December 2020

Prevention of motoneuron death by adenovirus-mediated neurotrophic factors

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12 December 2020

Identification and characterization of GFRalpha-3, a novel Co-receptor belonging to the glial cell line-derived neurotrophic receptor family

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12 December 2020

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

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12 December 2020

Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population.

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12 December 2020

GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine.

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12 December 2020

A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor

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12 December 2020

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

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12 December 2020

GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin

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12 December 2020

Characterization of a multicomponent receptor for GDNF.

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12 December 2020

Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease

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12 December 2020

Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report).

1 reference

12 December 2020

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

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12 December 2020

Glial cell line-derived neurotrophic factor sustains axotomized basal forebrain cholinergic neurons in vivo: dose-response comparison to nerve growth factor and brain-derived neurotrophic factor.

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12 December 2020

Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro

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12 December 2020

Functional receptor for GDNF encoded by the c-ret proto-oncogene

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12 December 2020

The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis.

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12 December 2020

Dopaminergic neurons protected from degeneration by GDNF gene therapy

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12 December 2020

Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.

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12 December 2020

The molecular basis of embryonic kidney development

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12 December 2020

GDNF reduces apoptosis in dopaminergic neurons in vitro

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12 December 2020

Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma

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12 December 2020

Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization

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12 December 2020

Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3

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12 December 2020

The tip-top branching ureter

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12 December 2020

Molecular heterogeneity of RET loss of function in Hirschsprung's disease

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12 December 2020

A new mouse mutant with progressive motor neuronopathy.

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12 December 2020

Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies

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12 December 2020

Renal and neuronal abnormalities in mice lacking GDNF

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12 December 2020

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

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12 December 2020

Hirschsprung's disease. Evaluation of mortality and long-term function in 260 cases

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12 December 2020

GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

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12 December 2020

GDNF signalling through the Ret receptor tyrosine kinase

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12 December 2020

Expression of the c-ret proto-oncogene during mouse embryogenesis

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12 December 2020

A structural superfamily of growth factors containing a cystine knot motif

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12 December 2020

Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease

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12 December 2020

Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins

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12 December 2020

Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons.

1 reference

12 December 2020

Nomenclature of GPI-linked receptors for the GDNF ligand family. GFR(alpha) Nomenclature Committee

1 reference

12 December 2020

Spatial and temporal expression of the ret proto-oncogene product in embryonic, infant and adult rat tissues.

1 reference

12 December 2020

Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases

1 reference

12 December 2020

Regulation of spinal motoneuron survival by GDNF during development and following injury

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12 December 2020

Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor

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12 December 2020

Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFR alpha after sciatic nerve lesion in the mouse

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12 December 2020

A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group

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12 December 2020

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

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12 December 2020

Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase

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12 December 2020

MPTP and other Parkinson-inducing agents

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12 December 2020

Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium

1 reference

12 December 2020

Nerve growth factor receptor and choline acetyltransferase colocalization in neurons within the rat forebrain: response to fimbria-fornix transection

1 reference

12 December 2020

Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B

1 reference

12 December 2020

Mutations of the RET proto-oncogene in Hirschsprung's disease

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12 December 2020

Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation

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12 December 2020

A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group

1 reference

12 December 2020

Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs

1 reference

12 December 2020

Defects in enteric innervation and kidney development in mice lacking GDNF

1 reference

12 December 2020

The neurotrophins and CNTF: two families of collaborative neurotrophic factors

1 reference

12 December 2020

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

1 reference

12 December 2020

Dose response to intraventricular glial cell line-derived neurotrophic factor administration in parkinsonian monkeys

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12 December 2020

Turning behaviour in animals

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12 December 2020

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.

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12 December 2020

Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons

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12 December 2020

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

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12 December 2020

Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium.

1 reference

12 December 2020

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

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12 December 2020

Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion

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12 December 2020

Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo

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12 December 2020

GFRalpha-4, a new GDNF family receptor

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12 December 2020

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

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12 December 2020

Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS.

1 reference

12 December 2020

Expression of ret in the chicken embryo suggests roles in regionalisation of the vagal neural tube and somites and in development of multiple neural crest and placodal lineages.

1 reference

12 December 2020

Expression and regulation of GFRalpha3, a glial cell line-derived neurotrophic factor family receptor

1 reference

12 December 2020

Long-term survival effects of GDNF on neonatal rat facial motoneurons after axotomy

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12 December 2020

Cloning, mRNA distribution and chromosomal localisation of the gene for glial cell line-derived neurotrophic factor receptor beta, a homologue to GDNFR-alpha

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12 December 2020

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

1 reference

12 December 2020

Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group

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12 December 2020

GDNF is an age-specific survival factor for sensory and autonomic neurons

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12 December 2020

TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.

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12 December 2020

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

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12 December 2020

GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo

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12 December 2020

GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice.

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12 December 2020

Persephin, a novel neurotrophic factor related to GDNF and neurturin

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12 December 2020

GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle

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12 December 2020

Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis

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12 December 2020

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12 December 2020

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

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12 December 2020

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

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12 December 2020

Functional recovery in parkinsonian monkeys treated with GDNF

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12 December 2020

Identifiers

DOI

10.1007/BF02741377

1 reference

PubMed ID

10321971

Dimensions Publication ID

25 September 2017

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1 reference

PubMed ID

10321971