(Q40970549)

25 September 2017

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title

Hereditary cancer: two hits revisited (English)

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25 September 2017

A G Knudson

1

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25 September 2017

1 January 1996

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Journal of Cancer Research and Clinical Oncology

25 September 2017

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25 September 2017

122

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25 September 2017

135-140

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25 September 2017

3

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https://scigraph.springernature.com/pub.10.1007/bf01366952

25 September 2017

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cites work

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p53 functions as a cell cycle control protein in osteosarcomas

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Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

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Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

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Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14

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The approaching era of the tumor suppressor genes

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Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

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Interstitial deletion of short arm of chromosome 11 limited to Wilms' tumor cells in a patient without aniridia

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Development of homozygosity for chromosome 11p markers in Wilms' tumour

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Structural evidence for the authenticity of the human retinoblastoma gene

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Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

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Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

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Identification of a chromosome 18q gene that is altered in colorectal cancers

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Mutation and cancer: neuroblastoma and pheochromocytoma

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Familial Breast Cancer, Soft-Tissue Sarcomas, and Other Neoplasms

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12 December 2020

Identification and characterization of the familial adenomatous polyposis coli gene

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T antigen is bound to a host protein in SY40-transformed cells

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Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients

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p53 protein expression in ulcerative colitis-associated colorectal dysplasia and carcinoma

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Mutation of a mutL homolog in hereditary colon cancer

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A genetic model for colorectal tumorigenesis

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12 December 2020

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12 December 2020

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.

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12 December 2020

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

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Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

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12 December 2020

Mutation and cancer: statistical study of retinoblastoma

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12 December 2020

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A general theory of carcinogenesis

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Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer

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12 December 2020

Patient with 13 Chromosome Deletion: Evidence That the Retinoblastoma Gene Is a Recessive Cancer Gene

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Mutation and cancer: a model for Wilms' tumor of the kidney

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12 December 2020

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours.

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12 December 2020

Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23)

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12 December 2020

Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D

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12 December 2020

Antioncogenes and human cancer

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12 December 2020

Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP).

1 reference

12 December 2020

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

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12 December 2020

Identifiers

DOI

10.1007/BF01366952

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25 September 2017

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PubMed ID

8601560