(Q40996680)

25 September 2017

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title

A review and investigation into the mechanistic basis of the genotoxicity of antihistamines (English)

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25 September 2017

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Snyder RD

1

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25 September 2017

language of work or name

English

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publication date

1 November 1998

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25 September 2017

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25 September 2017

volume

411

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25 September 2017

issue

3

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25 September 2017

page(s)

235-248

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Amplification of bleomycin-mediated degradation of DNA

25 September 2017

cites work

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7 January 2021

Molecular basis for bleomycin amplification: conformational and stereoelectronic effects in unfused amplifiers

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7 January 2021

Enhancement of the activity of bleomycin by cysteamine in a micronucleus assay in G0 human lymphocytes

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7 January 2021

Measurement of micronuclei in lymphocytes

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7 January 2021

Potenial antitumor agents. 28. Deoxyribonucleic acid polyintercalating agents

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7 January 2021

Synthesis and DNA-binding properties of polyamine analogues

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7 January 2021

Mutagenicity tests with astemizole in vitro and in vivo

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7 January 2021

The induction of unscheduled DNA synthesis by antihistamines in primary hepatocyte cultures

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7 January 2021

Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: a comparison with bacterial mutagenicity using 218 compounds.

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7 January 2021

The micronucleus test as a simple model, in vivo, for teh evaluation of drug-induced chromosome aberrations. Comparative studies with 13 compounds

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7 January 2021

Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals.

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7 January 2021

A study of the potential genotoxicity of methapyrilene and related antihistamines using the hepatocyte/DNA repair assay

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7 January 2021

Mutagenicity testing of doxylamine succinate, an antinauseant drug

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7 January 2021

Nitrosation and mutagenicity of some amine drugs.

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7 January 2021

The evaluation of methapyrilene for bacterial mutation with metabolic activation by Aroclor-induced, methapyrilene-induced and noninduced rat-liver S9.

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Weak and unexpected mutagenicity to Salmonella of the rat hepatocarcinogen methapyrilene.

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7 January 2021

Chromosome analysis of trifluorothymidine-resistant L5178Y mouse lymphoma cell colonies

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7 January 2021

Methapyrilene is a genotoxic carcinogen: studies on methapyrilene and pyrilamine in the L5178Y/TK +/- mouse lymphoma assay.

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7 January 2021

Characterization of DNA repair elicited by carcinogens and drugs in the hepatocyte primary culture/DNA repair test

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7 January 2021

DNA damage induced by the antihistaminic drug methapyrilene hydrochloride

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7 January 2021

Genotoxicity, toxicity, and carcinogenicity of the antihistamine methapyrilene

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7 January 2021

Chemical enhancement of SA7 virus transformation of hamster embryo cells: evaluation by interlaboratory testing of diverse chemicals

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7 January 2021

The potent hepatocarcinogen methapyrilene induces mutations in L5178Y mouse lymphoma cells in the apparent absence of DNA adduct formation

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7 January 2021

DNA-cell-binding (DCB) assay for suspected carcinogens and mut agens

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7 January 2021

Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: evaluations of 108 chemicals

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7 January 2021

DNA-damaging activity of tripelennamine in primary cultures of human hepatocytes

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7 January 2021

Microbial transformation of the antihistaminic drug triprolidine hydrochloride

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7 January 2021

Liver tumors induced in rats by oral administration of the antihistaminic methapyrilene hydrochloride

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7 January 2021

Nonintercalative DNA-binding antitumour compounds

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7 January 2021

New aspects concerning the mechanism of action of tranquilizers. The influence of some tranquilizers on protein and nucleic acid syntheses

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7 January 2021

Relationships between DNA-binding kinetics and biological activity for the 9-aminoacridine-4-carboxamide class of antitumor agents

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7 January 2021

Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics

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7 January 2021

Review of the genotoxic properties of chlorpromazine and related phenothiazines.

1 reference

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7 January 2021

Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s

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7 January 2021

10.1016/S1383-5742(98)00016-7

Identifiers

DOI

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25 September 2017

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