(Q40997303)

English

Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer's disease pathogenesis.

scientific article published on 30 April 2015

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scholarly article

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Europe PubMed Central

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7 March 2020

Herpes simplex virus type 1 infection in neurons leads to production and nuclear localization of APP intracellular domain (AICD): implications for Alzheimer's disease pathogenesis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925093%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Alzheimer's disease

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Herpes simplex virus type 1

1 reference

based on heuristic

inferred from title

Livia Civitelli

1

1 reference

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7 March 2020

Maria Elena Marcocci

2

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7 March 2020

Roberto Piacentini

4

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7 March 2020

6

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7 March 2020

Giovanna De Chiara

7

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7 March 2020

Anna Teresa Palamara

8

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7 March 2020

author name string

Ignacio Celestino

3

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7 March 2020

Enrico Garaci

5

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7 March 2020

publication date

30 April 2015

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7 March 2020

Journal of NeuroVirology

1 reference

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7 March 2020

21

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7 March 2020

5

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7 March 2020

480-490

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7 March 2020

https://scigraph.springernature.com/pub.10.1007/s13365-015-0344-0

0 references

Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

APP processing induced by herpes simplex virus type 1 (HSV-1) yields several APP fragments in human and rat neuronal cells

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Infectious agents and neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Herpes simplex virus type 1 and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Nuclear signaling by the APP intracellular domain occurs predominantly through the amyloidogenic processing pathway

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

The GSK3 hypothesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Metabolic regulation of brain Abeta by neprilysin.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Human neprilysin is capable of degrading amyloid beta peptide not only in the monomeric form but also the pathological oligomeric form

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Herpes simplex virus type 1 infection induces oxidative stress and the release of bioactive lipid peroxidation by-products in mouse P19N neural cell cultures

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Increased level of active GSK-3beta in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Reactivation of HSV-1 in the brain of patients with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Plus-end tracking proteins, CLASPs, and a viral Akt mimic regulate herpesvirus-induced stable microtubule formation and virus spread

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Autophagy, amyloidogenesis and Alzheimer disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Evidence for antiviral activity of glutathione: in vitro inhibition of herpes simplex virus type 1 replication.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

HSV-1 promotes Ca2+ -mediated APP phosphorylation and Aβ accumulation in rat cortical neurons.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

HSV-1 and Alzheimer's disease: more than a hypothesis.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Herpes simplex virus type I induces the accumulation of intracellular β-amyloid in autophagic compartments and the inhibition of the non-amyloidogenic pathway in human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Progressive decrease of amyloid precursor protein carboxy terminal fragments (APP-CTFs), associated with tau pathology stages, in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Herpes simplex virus interferes with amyloid precursor protein processing

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Herpes simplex virus infection causes cellular beta-amyloid accumulation and secretase upregulation

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Alzheimer's disease-specific tau phosphorylation is induced by herpes simplex virus type 1.

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

APP processing in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS13365-015-0344-0

21 January 2018

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A putative role of the Amyloid Precursor Protein Intracellular Domain (AICD) in transcription.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau cleavage at D421 by caspase-3 is induced in neurons and astrocytes infected with herpes simplex virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific expression of rat neutral endopeptidase (neprilysin) mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trafficking and proteolytic processing of APP

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal cytoskeletal dynamic modification and neurodegeneration induced by infection with herpes simplex virus type 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deconstructing GSK-3: The Fine Regulation of Its Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25925093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13365-015-0344-0

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925093%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25925093%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

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