(Q409999)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

IPI

iron chaperone activity

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

2 iron, 2 sulfur cluster binding

1 reference

5 June 2018

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

oxidoreductase activity

1 reference

8 April 2019

3 references

5 June 2018

N-terminal iron-mediated self-cleavage of human frataxin: regulation of iron binding and complex formation with target proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

5 June 2018

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

5 June 2018

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

5 June 2018

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

5 June 2018

Dynamics, stability and iron-binding activity of frataxin clinical mutants

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

5 June 2018

Assembly of human frataxin is a mechanism for detoxifying redox-active iron

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Assembly of human frataxin is a mechanism for detoxifying redox-active iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

4 references

8 April 2019

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

N-terminal iron-mediated self-cleavage of human frataxin: regulation of iron binding and complex formation with target proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Dynamics, stability and iron-binding activity of frataxin clinical mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

3 references

L-cysteine desulfurase complex

1 reference

8 April 2019

Iron Sulfur and Molybdenum Cofactor Enzymes Regulate the Drosophila Life Cycle by Controlling Cell Metabolism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

In vivo maturation of human frataxin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

regulation of ferrochelatase activity

IBA

biological process

1 reference

8 April 2019

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

positive regulation of cell population proliferation

1 reference

8 April 2019

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

1 reference

8 April 2019

Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

iron-sulfur cluster assembly

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

positive regulation of aconitate hydratase activity

1 reference

8 April 2019

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

positive regulation of cell growth

1 reference

8 April 2019

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

cellular response to hydrogen peroxide

1 reference

8 April 2019

Assembly of human frataxin is a mechanism for detoxifying redox-active iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

negative regulation of release of cytochrome c from mitochondria

1 reference

8 April 2019

A pool of extramitochondrial frataxin that promotes cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

positive regulation of succinate dehydrogenase activity

1 reference

8 April 2019

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

protein autoprocessing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

negative regulation of apoptotic process

1 reference

8 April 2019

A pool of extramitochondrial frataxin that promotes cell survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

small molecule metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

iron incorporation into metallo-sulfur cluster

1 reference

5 June 2018

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16595&geneProductId=UniProtKB:Q16595

positive regulation of catalytic activity

1 reference

8 April 2019

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

iron-sulfur cluster assembly

oxidative phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

cellular iron ion homeostasis

4 references

8 April 2019

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

IBA

adult walking behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

embryo development ending in birth or egg hatching

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

iron incorporation into metallo-sulfur cluster

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

negative regulation of multicellular organism growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

negative regulation of organ growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16595

http://purl.uniprot.org/uniprot/Q16595

Gene Atlas image

PBB GE FXN 205565 s at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

Identifiers.org

has part(s)

Frataxin conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16595

Commons category

Frataxin

0 references

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

Transporter Classification Database ID

1 reference

9.B.21.1.1

2 references

Transporter Classification database

retrieved

13 March 2020