(Q24294287)

positive regulation of lyase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Ilaria Guccini

3

0 references

Ivano Condò

object named as

Ivano Condò

1

0 references

Florence Malisan

object named as

Florence Malisan

2

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author name string

Dario Serio

4

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Alessandra Rufini

5

0 references

Roberto Testi

Metabolic regulation of citrate and iron by aconitases: role of iron-sulfur cluster biogenesis

6

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language of work or name

English

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publication date

1 April 2010

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published in

Human Molecular Genetics

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volume

19

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issue

7

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page(s)

1221-9

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cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Increased IRP1 activity in Friedreich ataxia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Mechanisms for multiple intracellular localization of human mitochondrial proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Friedreich's ataxia: coenzyme Q10 and vitamin E therapy

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Iron dysregulation in Friedreich ataxia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Iron-sulfur cluster biogenesis and human disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

The aconitase family: three structural variations on a common theme

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Characterization of an Iron−Sulfur Cluster Assembly Protein (ISU1) fromSchizosaccharomyces pombe†

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Peroxynitrite and nitric oxide differently target the iron-sulfur cluster and amino acid residues of human iron regulatory protein 1.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Localization and functionality of microsporidian iron-sulphur cluster assembly proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

The role of iron regulatory proteins in mammalian iron homeostasis and disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Diagnosis and treatment of Friedreich ataxia: a European perspective

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Single translation--dual destination: mechanisms of dual protein targeting in eukaryotes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Acidic residues of yeast frataxin have an essential role in Fe-S cluster assembly

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Reversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Activation of iron regulatory protein-1 by oxidative stress in vitro

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Human Cytoplasmic Aconitase (Iron Regulatory Protein 1) Is Converted into Its [3Fe-4S] Form by Hydrogen Peroxidein Vitrobut Is Not Activated for Iron-responsive Element Binding

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Mitochondrial and cytosolic isoforms of yeast fumarase are derivatives of a single translation product and have identical amino termini

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Detection of a [3Fe-4S] cluster intermediate of cytosolic aconitase in yeast expressing iron regulatory protein 1. Insights into the mechanism of Fe-S cluster cycling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

A pool of extramitochondrial frataxin that promotes cell survival

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Roles of the mammalian cytosolic cysteine desulfurase, ISCS, and scaffold protein, ISCU, in iron-sulfur cluster assembly

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Evidence that phosphorylation of iron regulatory protein 1 at Serine 138 destabilizes the [4Fe-4S] cluster in cytosolic aconitase by enhancing 4Fe-3Fe cycling

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

The structure and function of frataxin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Friedreich ataxia: the oxidative stress paradox

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Frataxin interacts functionally with mitochondrial electron transport chain proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

RNAi-mediated suppression of the mitochondrial iron chaperone, frataxin, in Drosophila

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

In vivo maturation of human frataxin

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Extra-mitochondrial localisation of frataxin and its association with IscU1 during enterocyte-like differentiation of the human colon adenocarcinoma cell line Caco-2.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

The mitochondrial targeting sequence tilts the balance between mitochondrial and cytosolic dual localization.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021

Pharmacotherapy for Friedreich ataxia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP592

7 January 2021