(Q41002651)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Chemical synthesis and biological properties of novel fluorescent antifolates in Pgp- and MRP-overexpressing tumour cell lines (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

4

1 reference

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5 December 2019

author name string

C Robson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

K A Wright

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

P R Twentyman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

R J Griffin

5

1 reference

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5 December 2019

language of work or name

English

0 references

publication date

1 October 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

published in

Biochemical Pharmacology

1 reference

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5 December 2019

volume

56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

page(s)

807-816

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

Clinical Science Review: Update on Trimetrexate, a Folate Antagonist with Antineoplastic and Antiprotozoal Properties

5 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

The renewed potential for folate antagonists in contemporary cancer chemotherapy

7 January 2021

1 reference

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New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii

7 January 2021

1 reference

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Biochemistry of multidrug resistance mediated by the multidrug transporter

7 January 2021

1 reference

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Biology of the multidrug resistance-associated protein, MRP.

7 January 2021

1 reference

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Cross resistance of pleiotropically drug resistant P338 leukemia cells to the lipophilic antifolates trimetrexate and BW 301U.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

7 January 2021

1 reference

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Clinical trials of agents that reverse multidrug resistance. A literature review

7 January 2021

1 reference

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Structural studies on bioactive compounds. 8. Synthesis, crystal structure, and biological properties of a new series of 2,4-diamino-5-aryl-6-ethylpyrimidine dihydrofolate reductase inhibitors with in vivo activity against a methotrexate-resistant t

7 January 2021

1 reference

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Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.

7 January 2021

1 reference

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Derivation and preliminary characterisation of adriamycin resistant lines of human lung cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Enzyme kinetic studies in cell populations using fluorogenic substrates and flow cytometric techniques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Structural studies on bio-active compounds. 20. Molecular modeling and crystallographic studies on methylbenzoprim, a potent inhibitor of dihydrofolate reductase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Reaction of reactive sulfhydryl groups of creatine kinase with dansyl chloride

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

7-chloro-4-nitrobenzo-2-oxa-1,3-diazole: a new fluorigenic reagent for amino acids and other amines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Identification of methotrexate transport deficiency in mammalian cells using fluoresceinated methotrexate and flow cytometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Use of fluorescence-activated cell sorter to isolate mutant mammalian cells deficient in an internal protein, dihydrofolate reductase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

A fluorescein-methotrexate-based flow cytometric bioassay for measurement of plasma methotrexate and trimetrexate levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

P-glycoprotein confers methotrexate resistance in 3T6 cells with deficient carrier-mediated methotrexate uptake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

Dihydrofolate reductase as a therapeutic target

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900068-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(98)00068-9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774142%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference