(Q41004810)

English

Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase

scientific article published on January 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

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1 reference

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author name string

Belcourt MF

1

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Hodnick WF

2

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Rockwell S

3

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Sartorelli AC

4

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

publication date

1 January 1998

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Advances in Enzyme Regulation

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

38

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

111-133

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

Tumor hypoxia: its impact on cancer therapy

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The hypoxic tumor cell: a target for selective cancer chemotherapy

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The histological structure of some human lung cancers and the possible implications for radiotherapy

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells

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Diversity of penetration of anti-cancer agents into solid tumours

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Physiologic Mechanisms of Therapeutic Resistance: Blood Flow and Hypoxia

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Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells

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Frequencies of independent and simultaneous selection of Chinese hamster cells for methotrexate and doxorubicin (adriamycin) resistance

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Mitomycin C as an adjunct to postoperative radiation therapy in squamous cell carcinoma of the head and neck: results from two randomized clinical trials

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Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer

1 reference

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Mitomycin C: small, fast and deadly (but very selective)

1 reference

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Recognition of specific DNA sequences by mitomycin C for alkylation

1 reference

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DNA sequence specificity of mitomycin cross-linking

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Recognition between mitomycin C and specific DNA sequences for cross-link formation

1 reference

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Metabolic activation of mitomycin C by liver microsomes and nuclei

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NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals

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Generation of hydroxyl radical by anticancer quinone drugs, carbazilquinone, mitomycin C, aclacinomycin A and adriamycin, in the presence of NADPH-cytochrome P-450 reductase

1 reference

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Bioreductive activation of mitomycin C by DT-diaphorase

1 reference

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Increased sensitivity of quinone resistant cells to mitomycin C.

1 reference

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Bioactivation of Mitomycin C by Xanthine Dehydrogenase From EMT6 Mouse Mammary Carcinoma Tumors

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Characterization of a human bladder cancer cell line selected for resistance to mitomycin C.

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Mechanism of differential sensitivity of human bladder cancer cells to mitomycin C and its analogue

1 reference

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Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2897%2900009-5

7 January 2021

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Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase

1 reference

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7 January 2021

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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

1 reference

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Rat liver NAD(P)H:quinone oxidoreductase: cDNA expression and site-directed mutagenesis

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The scanning model for translation: an update

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Purification and properties of soluble NADH-cytochrome b5 reductase of rabbit erythrocytes

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Measurement of protein using bicinchoninic acid

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Mitomycin C sensitivity in human bladder cancer cells: possible role of glutathione and glutathione transferase in resistance

1 reference

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One-electron-transfer reactions in biochemical systems. 3. One-electron reduction of quinones by microsomal flavin enzymes

1 reference

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DNA cross-linking by intermediates in the mitomycin activation cascade

1 reference

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1 reference

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1 reference

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Gene targeting of DT-diaphorase in mouse embryonic stem cells: establishment of null mutant and its mitomycin C-resistance.

1 reference

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1 reference

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Identifiers

10.1016/S0065-2571(97)00009-5

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

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