(Q41017471)

English

Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency

scientific article published on June 1988

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

Elastase regulates the synthesis of its inhibitor, alpha 1-proteinase inhibitor, and exaggerates the defect in homozygous PiZZ alpha 1 PI deficiency (English)

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

1 reference

based on heuristic

inferred from title

author name string

D H Perlmutter

1

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

J Travis

2

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

P I Punsal

3

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

language of work or name

0 references

publication date

1 June 1988

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

81

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

1774-1780

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

Induction of prothrombin synthesis by prothrombin fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

The isolation of a clone for human alpha 1-antitrypsin and the detection of alpha 1-antitrypsin in mRNA from liver and leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Regulation of fibrinogen synthesis by plasmin-derived fragments of fibrinogen and fibrin: an indirect feedback pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Monoclonal antibodies specific for Escherichia coli J5 lipopolysaccharide: cross-reaction with other gram-negative bacterial species.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Human plasma proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Efficient translation of tobacco mosaic virus RNA and rabbit globin 9S RNA in a cell-free system from commercial wheat germ

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

A fast-acting elastase inhibitor in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

The cellular defect in alpha 1-proteinase inhibitor (alpha 1-PI) deficiency is expressed in human monocytes and in Xenopus oocytes injected with human liver mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Expression of the alpha 1-proteinase inhibitor gene in human monocytes and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Expression of complement proteins C2 and factor B in transfected L cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Cathepsin L inactivates alpha 1-proteinase inhibitor by cleavage in the reactive site region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Expression of the alpha-1-antitrypsin gene in mononuclear phagocytes of normal and alpha-1-antitrypsin-deficient individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

A lymphokine regulates expression of alpha-1-proteinase inhibitor in human monocytes and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Molecular abnormality of human alpha1-antitrypsin variant (Pi-ZZ) associated with plasma activity deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Characterization of a Peptide Released during the Reaction of Human β1–Antitrypsin and Bovine β-Chymotrypsin1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

α-1-Antitrypsin: Sequence of the Z variant tryptic peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Cultured human monocytes synthesize and secrete alpha2-macroglobulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

26 September 2017

Biosynthesis in vitro of complement subcomponents C1q, C1s and C1̅ inhibitor by resting and stimulated human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Changes in serum proteinase inhibitor levels following bone surgery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Lipopolysaccharide modulates the expression of alpha 1 proteinase inhibitor and other serine proteinase inhibitors in human monocytes and macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Identification of a second mutation in the protein-coding sequence of the Z type alpha 1-antitrypsin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Regulation of class III major histocompatibility complex gene products by interleukin-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Cell-specific expression of a transfected human alpha 1-antitrypsin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Synthesis of the second component of complement by long-term primary cultures of human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Human alpha-1-antichymotrypsin: interaction with chymotrypsin-like proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

17 June 2018

Limited proteolysis by macrophage elastase inactivates human alpha 1-proteinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

19 August 2018

Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=442624

19 August 2018

Human leukocyte granule elastase: rapid isolation and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human alpha-1-proteinase inhibitor mechanism of action: Evidence for activation by limited proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung function studies in asymptomatic individuals with moderately (Pi SZ) and severely (Pi Z) reduced levels of alpha1-antitrypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural evidence for methionine at the reactive site of human alpha-1-proteinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of Subcomponents Clq, Cl[rbar] and Cl[sbar] of the First Component of Complement from Cohn Fraction I by Affinity Chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of oxidized alpha-1-proteinase inhibitor in serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat factor X is synthesized as a single chain precursor inducible by prothrombin fragments

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

α1-Antitrypsin deficiency detection by direct analysis of the mutation in the gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement biosynthesis by human bronchoalveolar macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective study of children with alpha 1-antitrypsin deficiency: eight-year-old follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenopusoocytes can synthesise but do not secrete the Z variant of human α1-antitrypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct primary translation products from human liver mRNA give rise to secreted and cell-associated forms of complement protein C2

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the serine proteases leukocyte elastase, pancreatic elastase, cathepsin G, and chymotrypsin by peptide boronic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific pretranslational regulation of complement production in human mononuclear phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1-antitrypsin deficiency and emphysema caused by homozygous inheritance of non-expressing alpha 1-antitrypsin genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis, processing, and secretion of M and Z variant human alpha 1-antitrypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/3260245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI113519

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

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