(Q41020127)

25 September 2017

title

A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals (English)

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25 September 2017

Goto D

1

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25 September 2017

Yagi K

2

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25 September 2017

Inoue H

3

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25 September 2017

Iwamoto I

4

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25 September 2017

Kawabata M

5

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25 September 2017

Miyazono K

6

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25 September 2017

Kato M

7

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25 September 2017

language of work or name

English

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publication date

1 July 1998

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25 September 2017

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25 September 2017

volume

430

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25 September 2017

issue

3

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25 September 2017

page(s)

201-204

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Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).

25 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

TGF-beta signalling through the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Tumor suppressor activity of the TGF-beta pathway in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Characterization of functional domains within Smad4/DPC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

DPC4 (SMAD4) mediates transforming growth factor-beta1 (TGF-beta1) induced growth inhibition and transcriptional response in breast tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

A human keratinocyte cell line produces two autocrine growth inhibitors, transforming growth factor-beta and insulin-like growth factor binding protein-6, in a calcium- and cell density-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Smad6 inhibits signalling by the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

Somatic alterations of the DPC4 gene in human colorectal cancers in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2900658-9

10.1016/S0014-5793(98)00658-9

7 January 2021

Identifiers

DOI

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25 September 2017

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