(Q41021738)

English

Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

scientific article published on June 1998

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scholarly article

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Europe PubMed Central

25 September 2017

Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP). (English)

1 reference

Europe PubMed Central

25 September 2017

author name string

Watson CY

1

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Europe PubMed Central

25 September 2017

Whish WJ

2

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Europe PubMed Central

25 September 2017

Threadgill MD

3

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25 September 2017

language of work or name

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publication date

1 June 1998

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25 September 2017

Bioorganic & Medicinal Chemistry

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25 September 2017

6

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Europe PubMed Central

25 September 2017

6

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25 September 2017

721-734

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Europe PubMed Central

25 September 2017

Inhibitors of Poly(ADP-Ribose) Synthesis Enhance X-Ray Killing of Log-Phase Chinese Hamster Cells

1 reference

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Inhibition of Gamma-Ray Dose-Rate Effects by D 2 O and Inhibitors of Poly(ADP-Ribose) Synthetase in Cultured Mammalian L5178Y Cells

1 reference

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The role of inhibitors of poly(ADP-ribose) polymerase as resistance-modifying agents in cancer therapy.

1 reference

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Enhancement of alkylating agent activity in vitro by PD 128763, a potent poly(ADP-ribose) synthetase inhibitor

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Potentiation of the antitumor activity of cisplatin in mice by 3-aminobenzamide and nicotinamide

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3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity

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Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors

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DNA strand break-mediated partitioning of poly(ADP-ribose) polymerase function

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Novel inhibitors of poly(ADP-ribose) synthetase

1 reference

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Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships

1 reference

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Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken

1 reference

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The crystal structure of diphtheria toxin

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Refined structure of monomeric diphtheria toxin at 2.3 A resolution

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Refined structure of dimeric diphtheria toxin at 2.0 A resolution

1 reference

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Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide

1 reference

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Crystal structure of nucleotide-free diphtheria toxin

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Facile synthesis of glycol metabolites of phenethylamine drugs

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.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

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Synthesis and cytotoxic activity of C-glycosidic nicotinamide riboside analogs

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The synthesis of quinoline- and isoquinolinecarboxaldehydes

1 reference

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Molecular mechanisms in the control of translation by hormones and growth factors

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Cellular mono(ADP-ribosyl) transferase inhibits protein synthesis.

1 reference

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Identifiers

10.1016/S0968-0896(98)00029-7

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

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