(Q41022255)

English

Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation

scientific article published on December 1, 1992

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scholarly article

1 reference

Europe PubMed Central

25 September 2017

Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1334978

15 September 2022

tosyl compounds

1 reference

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15 September 2022

author name string

C. B. Glaser

1

1 reference

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15 September 2022

J. Morser

2

1 reference

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15 September 2022

J. H. Clarke

3

1 reference

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15 September 2022

E. Blasko

4

1 reference

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15 September 2022

K. McLean

5

1 reference

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15 September 2022

I. Kuhn

6

1 reference

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15 September 2022

R. J. Chang

7

1 reference

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15 September 2022

J. H. Lin

8

1 reference

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15 September 2022

L. Vilander

9

1 reference

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15 September 2022

W. H. Andrews

10

1 reference

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15 September 2022

D. R. Light

11

1 reference

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15 September 2022

language of work or name

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publication date

1 December 1992

1 reference

Europe PubMed Central

25 September 2017

full work available at URL

https://europepmc.org/articles/PMC443416

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1334978

15 September 2022

https://europepmc.org/articles/PMC443416?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1334978

15 September 2022

Journal of Clinical Investigation

1 reference

Europe PubMed Central

25 September 2017

90

1 reference

Europe PubMed Central

25 September 2017

6

1 reference

Europe PubMed Central

25 September 2017

2565-2573

1 reference

Europe PubMed Central

25 September 2017

Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity

1 reference

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26 September 2017

Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar lavage fluid

1 reference

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26 September 2017

Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1

1 reference

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26 September 2017

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase

1 reference

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26 September 2017

Oxygen-derived radicals: a link between reperfusion injury and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Characterization of a thrombomodulin cDNA reveals structural similarity to the low density lipoprotein receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Oxygen-derived free radicals in postischemic tissue injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade

1 reference

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26 September 2017

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Oxidants and human disease: some new concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Sequence of a cDNA for mouse thrombomodulin and comparison of the predicted mouse and human amino acid sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Tissue destruction by neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Stable expression of a secretable deletion mutant of recombinant human thrombomodulin in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Structure-function studies of the epidermal growth factor domains of human thrombomodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

The oxidative inactivation of human alpha-1-proteinase inhibitor. Further evidence for methionine at the reactive center

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

15 Cleavage at aspartylprolyl bonds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

26 September 2017

Inactivation of plasminogen activator inhibitor by oxidants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

The inhibitory effects of some iodonium compounds on the superoxide generating system of neutrophils and their failure to inhibit diaphorase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

TNF as a mediator of cardiac transplant rejection, including effects on the intragraft protein C/protein S/thrombomodulin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Structurally homologous ligand binding of integrin Mac-1 and viral glycoprotein C receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Regulation of thrombomodulin by tumor necrosis factor-alpha: comparison of transcriptional and posttranscriptional mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Activated and unactivated platelet adhesion to monocytes and neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Role of leukocytes in the activation of intravascular coagulation in patients with septicemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Aspartic acid 349 in the fourth epidermal growth factor-like structure of human thrombomodulin plays a role in its Ca(2+)-mediated binding to protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Isolation and characterization of alpha-1-antitrypsin from the Cohn fraction IV-I of human plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

14 June 2018

Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

17 June 2018

Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

17 June 2018

Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

17 June 2018

Reaction of bovine growth hormone with hydrogen peroxide.

1 reference

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17 June 2018

Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443416

19 August 2018

Structural evidence for methionine at the reactive site of human alpha-1-proteinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The turnover of thrombin-thrombomodulin complex in cultured human umbilical vein endothelial cells and A549 lung cancer cells. Endocytosis and degradation of thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthesis and analytical use of a highly sensitive and convenient substrate of elastase

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidized N-formylmethionyl-leucyl-phenylalanine: effect on the activation of human monocyte and neutrophil chemotaxis and superoxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotactic factor inactivation by myeloperoxidase-mediated oxidation of methionine

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin blocks the ability of thrombin to activate platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-lived oxidants generated by human neutrophils: characterization and bioactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of human coagulation factor V by activated protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The binding and regulation of protein S by neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral activation of the coagulation cascade: molecular interactions at the surface of infected endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative inactivation of purified human alpha-2-antiplasmin, antithrombin III, and C1-inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/1334978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI116151

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

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