(Q41030710)

English

Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases

scientific article published on February 1979

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scholarly article

1 reference

Europe PubMed Central

25 September 2017

Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues. Evidence for oxirane formation by P450-linked microsomal mono-oxygenases (English)

1 reference

Europe PubMed Central

25 September 2017

author name string

H Bartsch

1

1 reference

Europe PubMed Central

25 September 2017

C Malaveille

2

1 reference

Europe PubMed Central

25 September 2017

A Barbin

3

1 reference

Europe PubMed Central

25 September 2017

G Planche

4

1 reference

Europe PubMed Central

25 September 2017

publication date

1 February 1979

1 reference

Europe PubMed Central

25 September 2017

Archives of Toxicology

1 reference

Europe PubMed Central

25 September 2017

41

1 reference

Europe PubMed Central

25 September 2017

249-277

1 reference

Europe PubMed Central

25 September 2017

4

1 reference

Europe PubMed Central

25 September 2017

https://scigraph.springernature.com/pub.10.1007/bf00296896

0 references

Mutagenic and carcinogenic effects of vinyl chloride

1 reference

https://api.crossref.org/works/10.1007%2FBF00296896

21 January 2018

Mutagenic and carcinogenic N-nitroso compounds: possible environmental hazards

1 reference

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21 January 2018

Mutagenic and lethal effects of α-benzene hexachloride, dibutyl phthalate and trichloroethylene in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1007%2FBF00296896

21 January 2018

Biochemical toxicology of unsaturated halogenated monomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

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Carcinogenicity of trichloroethylene: fact or artifact?

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

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Bioassay of tetrachloroethylene for possible carcinogenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

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IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: cadmium, nickel, some epoxides, miscellaneous industrial chemicals and general consideration on volatile anaesthetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

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Human, rat and mouse liver-mediated mutagenicity of vinyl chloride inS. typhimurium strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic activity of trichloroethylene in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

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Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenicity of vinyl chloride, chloroethyleneoxide, chloroacetaldehyde and chloroethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

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Factors for efficiency of the Salmonella/microsome mutagenicity assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

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Tissue-mediated mutagenicity of vinylidene chloride and 2-chlorobutadiene in Salmonella typhimurium

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

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Comment on the mutagenic effectiveness of vinyl chloride metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of modifiers of hepatic microsomal drug metabolism and the inhalation toxicity of 1,1-dichloroethylene

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of (1,2-14C) vinyl chloride in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of gene mutations and gene conversions by vinyl chloride metabolites in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the metabolism and hepatotoxicity of trichloroethylene and perchloroethylene

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkylation of DNA and proteins in mice exposed to vinyl chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver-microsome-mediated formation of alkylating agents from vinyl bromide and vinyl chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the genetic effects induced by vinyl chloride monomer (VCM) under mammalian metabolic activation: studies in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

METABOLISM OF DISULFIRAM AND DIETHYLDITHIOCARBAMATE IN RATS WITH DEMONSTRATION OF AN IN VIVO ETHANOL-INDUCED INHIBITION OF THE GLUCURONIC ACID CONJUGATION OF THE THIOL

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemistry and biogenesis of the S-containing metabolites of vinyl chloride in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vinyl chloride-induced depression of hepatic non-protein sulfhydryl content and effects on bromosulphalein (BSP) clearance in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Industrial mutagens and potential mutagens I. Halogenated aliphatic derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of vinyl chloride with rat-liver DNA in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the hepatotoxicity of trichloroethylene by inducers of drug metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat liver microsomes catalyse covalent binding of 14C-vinyl chloride to macromolecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vinyl chloride-induced deactivation of cytochrome P-450 and other components of the liver mixed function oxidase system: an in vivo study

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the possible mechanism of carcinogenic action of vinyl chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogenicity bioassays of vinyl chloride: current results

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Aminoacetonitrile on the Metabolism of Dimethylnitrosamine and Methylation of RNA During Liver Carcinogenesis2

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatotoxicity of vinyl chloride and 1,1-dichloroethylene. Role of mixed function oxidase system

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenicity of butadiene and butadiene monoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biological fate of vinylidene chloride in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-mutagenicity and -recombinogenicity of vinyl chloride in the absence of metabolic activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of hepatic microsomal drug metabolism in the rat during daily disulfiram administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiosarcoma of liver in the manufacture of polyvinyl chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of chlorinated alkenes and alkanes as related to toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vinyl chloride dependent mutagensis: Effects of liver extracts and free radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of 1,1-Dichloroethylene Toxicity by Pretreatment of Fasted Male Rats with 2,3-Epoxypropan-1-01

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interaction of vinyl chloride with rat hepatic microsomal cytochrome P-450 in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogenicity of halo-ethers. II. Structure-activity relationships of analogs of bis(chloromethyl)ether

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation induction in chinese hamster V79 cells by two vinyl chloride metabolites, chloroethylene oxide and 2-chloroacetaldehyde

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of various treatments on toxicity of inhaled vinylidene chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogenic activity of di- and trifunctional alpha-chloro ethers and of 1,4-dichlorobutene-2 in ICR/HA swiss mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenicity and metabolism of vinyl chloride and related compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hepatotoxicity of ethylene, vinyl fluoride, vinyl chloride, and vinyl bromide after aroclor 1254 pretreatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver microsomal uptake of 614C9vinyl chloride and transformation to protein alkylating metabolites in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolites in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkylation of RNA by vinyl chloride metabolites in vitro and in vivo: formation of 1-N(6)-etheno-adenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical modification of acute hepatotoxicity of vinyl chloride monomer in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/373707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00296896

1 reference

Europe PubMed Central

25 September 2017

1 reference

Europe PubMed Central

25 September 2017

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