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Mechanisms underlying T-cell tolerance
scientific article published on April 1996
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
review article
1 reference
stated in
Europe PubMed Central
title
Mechanisms underlying T-cell tolerance
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
author name string
Kruisbeek AM
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
Amsen D
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
publication date
1 April 1996
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
volume
8
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
page(s)
233-244
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
cites work
Thymic selection: two pathways to life and two to death
1 reference
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Crossref
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T cell receptor antagonists and partial agonists
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Short-lived complexes between myelin basic protein peptides and IAk
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Low avidity recognition of self-antigen by T cells permits escape from central tolerance.
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Direct binding of autoimmune disease related T cell epitopes to purified Lewis rat MHC class II molecules
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Immunological function of a defined T-cell population tolerized to low-affinity self antigens
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Thymocyte lineage commitment: is it instructed or stochastic?
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7 January 2021
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Molecular mechanisms underlying functional T-cell unresponsiveness.
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CTLA-4 can function as a negative regulator of T cell activation
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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
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7 January 2021
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Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?
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7 January 2021
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A negative regulatory function of B7 revealed in B7-1 transgenic mice
1 reference
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7 January 2021
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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
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7 January 2021
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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
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7 January 2021
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Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
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7 January 2021
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CD28-B7 interactions are not required for intrathymic clonal deletion
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7 January 2021
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Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.
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7 January 2021
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An essential role for gp39, the ligand for CD40, in thymic selection.
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7 January 2021
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The expansive role of CD40 and its ligand, gp39, in immunity
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7 January 2021
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Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses
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7 January 2021
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Induction of B cell costimulatory function by recombinant murine CD40 ligand
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Crossref
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7 January 2021
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Rapid induction of a novel costimulatory activity on B cells by CD40 ligand.
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Crossref
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7 January 2021
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CD40 ligand-transduced co-stimulation of T cells in the development of helper function
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Crossref
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7 January 2021
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Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand
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Crossref
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7 January 2021
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Peripheral clonal elimination of functional T cells
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7 January 2021
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Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity
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7 January 2021
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Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B
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7 January 2021
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Peripheral selection of the T cell repertoire
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7 January 2021
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Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
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Thymic and peripheral apoptosis of antigen-specific T cells might cooperate in establishing self tolerance.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
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The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo
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7 January 2021
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Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Intrathymic and extrathymic clonal deletion of T cells
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
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Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
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Clonal deletion as direct consequence of an in vivo T cell response to bacterial superantigen
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Exogenous superantigens acutely trigger distinct levels of peripheral T cell tolerance/immunosuppression: dose-response relationship.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A functionally compromised intermediate in extrathymic CD8+ T cell deletion.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Fatal interactions: Fas-induced apoptosis of mature T cells
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7 January 2021
based on heuristic
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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
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Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas ligand mediates activation-induced cell death in human T lymphocytes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
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inferred from DOI database lookup
Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)
1 reference
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7 January 2021
based on heuristic
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Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A role for CD95 ligand in preventing graft rejection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fas and Fas ligand: lpr and gld mutations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis in mature T cells by tumour necrosis factor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA4 mediates antigen-specific apoptosis of human T cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation interferes with the APO-1 pathway in mature human T cells.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A naturally occurring soluble isoform of murine Fas generated by alternative splicing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Self-ignorance in the peripheral T-cell pool
1 reference
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple levels of peripheral tolerance
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Levels of peripheral T cell tolerance induced by different doses of tolerogen
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
T cell awareness of paternal alloantigens during pregnancy
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell responsiveness to an oncogenic peripheral protein and spontaneous autoimmunity in transgenic mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fibroblasts as efficient antigen-presenting cells in lymphoid organs
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
T helper cell subsets in insulin-dependent diabetes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Relationships among antigen presentation, cytokines, immune deviation, and autoimmune disease
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphocyte responses and cytokines
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral deletion of antigen-reactive T cells in oral tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2896%2980062-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(96)80062-8
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
PubMed ID
8725947
1 reference
stated in
Europe PubMed Central
PubMed ID
8725947
retrieved
26 September 2017
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