(Q41054436)

26 September 2017

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title

Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2 and CNS-1 gliomas (English)

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26 September 2017

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Barth RF

1

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26 September 2017

1 January 1998

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Journal of Neuro-Oncology

26 September 2017

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26 September 2017

36

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26 September 2017

91-102

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26 September 2017

1

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PubMed ID

9525831

describes a project that uses

26 September 2017

9L

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exact match

https://scigraph.springernature.com/pub.10.1023/a:1005805203044

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cites work

Chemosensitization of the nitrosoureas by 2-nitroimidazoles in the subcutaneous 9L tumor model: pharmacokinetic and structure-activity considerations

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12 December 2020

Assessment of the experimental model of transplanted C6 glioblastoma in Wistar rats.

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12 December 2020

Identification of intracranial liqor metastases of experimental stereotactically implanted brain tumors by the tumor-selective MRI contrast agent MnTPPS

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12 December 2020

Insertion of ganglioside GM1 into rat glioma C6 cells renders them susceptible to growth inhibition by the B subunit of cholera toxin.

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12 December 2020

C6 glioma-astrocytoma cell and fetal astrocyte migration into artificial basement membrane: a permissive substrate for neural tumors but not fetal astrocytes

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12 December 2020

Biological and biochemical characterization of an interleukin 1-like factor from rat C6 glioma cells.

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12 December 2020

Tumor-specific transplantation immunity to intracerebral challenge with cells from a methylnitrosourea- induced brain tumor

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12 December 2020

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

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12 December 2020

Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boronophenylalanine.

1 reference

12 December 2020

Cerebrovascular effects and tumor kinetics after a single intratumoral injection of human recombinant interleukin-2 alone or in combination with intravenous chemotherapy in a rat model of glioma

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12 December 2020

Localization of experimental brain tumors in MRI by gadolinium porphyrin

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12 December 2020

The rat as an experimental animal

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12 December 2020

Systemic treatment with murine recombinant interleukin-1 beta inhibits the growth and progression of malignant glioma in the rat.

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12 December 2020

Morphological studies of rat brain tumors induced by N-nitrosomethylurea

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12 December 2020

Ganciclovir mediated regression of rat brain tumors expressing the herpes simplex virus thymidine kinase imaged by magnetic resonance

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12 December 2020

The mechanism and overcoming of resistance in ACNU-resistant sublines of C6 and 9L rat glioma.

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12 December 2020

Permeability Characteristics of Brain Adjacent to Tumors in Rats

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12 December 2020

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

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12 December 2020

Immunity to transplantable nitrosourea-induced neurogenic tumors. III. Systemic adoptive transfer of immunity.

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12 December 2020

Rat mitogen-stimulated lymphokine-activated T killer cells: production and effects on C6 glioma cells in vitro and in vivo in the brain of Wistar rats

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12 December 2020

Increased capillary permeability in rat brain induced by factors secreted by cultured C6 glioma cells: role in peritumoral brain edema.

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12 December 2020

Quantitative aspects of transplacental tumor induction with ethylnitrosourea in rats.

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12 December 2020

A comparative study on the pharmacokinetics and biodistribution of boronated porphyrin (BOPP) and sulfhydryl boron hydride (BSH) in the RG2 rat glioma model.

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12 December 2020

Enhanced boron uptake in RG 2 rat gliomas by electropermeabilization in vivo--a new possibility in boron neutron capture therapy

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12 December 2020

The effects of dexamethasone on experimental brain tumors: I. Transcapillary transport and blood flow in RG-2 rat gliomas.

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12 December 2020

Selective enhancement of radiation response of herpes simplex virus thymidine kinase transduced 9L gliosarcoma cells in vitro and in vivo by antiviral agents

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12 December 2020

Experimental brain tumors, with a report of those induced in dogs by Rous sarcoma virus

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12 December 2020

Curative potential of herpes simplex virus thymidine kinase gene transfer in rats with 9L gliosarcoma

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12 December 2020

Study of effectiveness of bleomycin in rat brain tumor model intravenously and intracerebrally

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12 December 2020

Cell kinetics of rat 9L brain tumors determined by double labeling with iodo- and bromodeoxyuridine

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12 December 2020

Immunobiology of primary intracranial tumors

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12 December 2020

The induction of tumors of the nervous system with intravenous methylnitrosourea.

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12 December 2020

Exploiting the lacZ reporter gene for quantitative analysis of disseminated tumor growth within the brain: use of the lacZ gene product as a tumor antigen, for evaluation of antigenic modulation, and to facilitate image analysis of tumor growth in s

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12 December 2020

Systemic chemotherapy combined with local adoptive immunotherapy cures rats bearing 9L gliosarcoma.

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12 December 2020

Correlation between Gd-enhanced MR imaging and histopathology in treated and untreated 9L rat brain tumors

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12 December 2020

Intracerebral chemotherapy in the 9L rat brain tumor model

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12 December 2020

Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of either sodium borocaptate or boronophenylalanine with or without blood-brain barrier disruption.

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12 December 2020

Radiation therapy of 9L rat brain tumors.

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12 December 2020

Differentiated rat glial cell strain in tissue culture.

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12 December 2020

Boron neutron capture therapy of a rat glioma.

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12 December 2020

Current brain tumour models with particular consideration of the transplantation techniques. Outline of literature and personal preliminary results.

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12 December 2020

The effect of AGM-1470 in an improved intracranial 9L gliosarcoma rat model.

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12 December 2020

Interstitial fluid pressure in intracranial tumours in patients and in rodents

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12 December 2020

Endothelial cell-based cytokine gene delivery inhibits 9L glioma growth in vivo.

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12 December 2020

Alterations in the synthesis of insulin-like growth factor binding proteins and insulin-like growth factors in rat C6 glioma cells transfected with a gap junction connexin43 cDNA.

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12 December 2020

Radiosurgery and fractionated radiation therapy: comparison of different techniques in an in vivo rat glioma model.

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12 December 2020

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

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12 December 2020

Treatment of autochthonous rat brain tumors with fractionated radiotherapy. The effects of graded radiation doses and of combined therapy with BCNU or steroids.

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12 December 2020

Increasing volume of distribution to the brain with interstitial infusion: dose, rather than convection, might be the most important factor.

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12 December 2020

Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1.

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12 December 2020

Migration of activated lymphocytes when adoptively transferred into cannulated rat brain

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12 December 2020

Regional metabolism of experimental brain tumors.

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12 December 2020

Invasion of experimental rat brain tumor: early morphological changes following microinjection of C6 glioma cells.

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12 December 2020

Invading C6 glioma cells maintaining tumorigenicity

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12 December 2020

Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: long-term follow-up by magnetic resonance imaging

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12 December 2020

Adoptive immunotherapy of a rat glioma using lymphokine-activated killer cells and interleukin 2.

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12 December 2020

Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors

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12 December 2020

Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA.

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12 December 2020

Neutron capture therapy of a rat glioma using boronophenylalanine as a capture agent.

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12 December 2020

Animal models for brain tumors: historical perspectives and future directions

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12 December 2020

BCNU and X-ray therapy of intracerebral 9L rat tumors

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12 December 2020

Treatment Schedule of Combination Using Radiation and ACNU in the Experimental Brain Tumors

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12 December 2020

The fine structure of intracranial neoplasms induced by the inoculation of avian sarcoma virus in neonatal and adult rats

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12 December 2020

Capillary junctions of the rat are not affected by osmotic opening of the blood-brain barrier.

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12 December 2020

Inoculation of C6 cell suspension into the brain of adult rats: immunohistochemical study.

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12 December 2020

Osmotic opening of the blood-brain barrier

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12 December 2020

Effects of γ-interferon on major histocompatibility complex antigen expression and lymphocytic infiltration in the 9L gliosarcoma brain tumor model: implications for strategies of immunotherapy

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12 December 2020

Insulin-like growth factor binding protein-4 gene expression is induced by transfection of gap junction connexin43 gene in a C6 glioma cell line.

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12 December 2020

Morphological characterization of nitrosourea-induced glioma cell lines and clones

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12 December 2020

In vivo microdialysis to characterize drug transport in brain tumors: analysis of methotrexate uptake in rat glioma-2 (RG-2)-bearing rats.

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12 December 2020

Regional measurements of blood-to-tissue transport in experimental RG-2 rat gliomas.

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12 December 2020

Adenovirally mediated gene transfer into experimental solid brain tumors and leptomeningeal cancer cells.

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12 December 2020

Permeability of different experimental brain tumor models to horseradish peroxidase.

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12 December 2020

Experimental brain tumors and edema in rats. I. Histology and cytology of tumors

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12 December 2020

Tissue distribution of methotrexate following administration as a solution and as a magnetic microsphere conjugate in rats bearing brain tumors.

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12 December 2020

The effect of nerve growth factor on undifferentiated glioma cells.

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12 December 2020

Intracranial administrations of single or multiple source allogeneic cytotoxic T lymphocytes: chronic therapy for primary brain tumors.

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12 December 2020

Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model

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12 December 2020

Blood flow and blood-to-tissue transport in 9L gliosarcomas: the role of the brain tumor model in drug delivery research

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12 December 2020

Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate.

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12 December 2020

Development of a xenograft glioma model in mouse brain.

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12 December 2020

Development of an animal brain tumor model and its response to therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea.

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12 December 2020

Uptake and retention of hematoporphyrin derivative in an in vivo/in vitro model of cerebral glioma.

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12 December 2020

The RG2 rat glioma model

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12 December 2020

RG-2 glioma growth attenuation and severe brain edema caused by local production of interleukin-2 and interferon-gamma.

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12 December 2020

Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms.

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12 December 2020

Analysis of interleukin 2 and various effector cell populations in adoptive immunotherapy of 9L rat gliosarcoma: allogeneic cytotoxic T lymphocytes prevent tumor take

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12 December 2020

Derivations of relative biological effectiveness for the high-let radiations produced during boron neutron capture irradiations of the 9L rat gliosarcoma in vitro and in vivo

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12 December 2020

Gene therapy of rat 9L gliosarcoma tumors by transduction with selectable genes does not require drug selection

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12 December 2020

The effects of irradiation on major histocompatibility complex expression and lymphocytic infiltration in the normal rat brain and the 9L gliosarcoma brain tumor model

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12 December 2020

A rat glioma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9L gliosarcoma

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12 December 2020

Inhibition of rat C6 glioblastoma tumor growth by expression of insulin-like growth factor I receptor antisense mRNA.

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12 December 2020

Effectiveness of controlled release of a cyclophosphamide derivative with polymers against rat gliomas.

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12 December 2020

In situ cyclopentenyl cytosine infusion for the treatment of experimental brain tumors

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12 December 2020

Localized proton NMR spectroscopy of experimental gliomas in rat brain in vivo

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12 December 2020

Factors influencing the cell type of brain tumors induced in dogs by Schmidt-Ruppin Rous sarcoma virus

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12 December 2020

Growth inhibition of intracerebral rat glioma by transfection-induced human interferon-beta.

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12 December 2020

Studies on the chemotherapy of experimental brain tumors: development of an experimental model

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12 December 2020

Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo

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12 December 2020

Regional measurements of blood flow in experimental RG-2 rat gliomas.

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12 December 2020

Neovascularization induced growth of implanted C6 glioma multicellular spheroids: magnetic resonance microimaging.

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12 December 2020

Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors.

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12 December 2020

A new glioma model in rat: the C6 spheroid implantation technique permeability and vascular characterization.

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12 December 2020

Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.

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12 December 2020

Enhanced effect of reserpine upon growth-inhibitory action of ACNU on ACNU-resistant C6 glioma

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12 December 2020

Polyamine metabolism in experimental brain tumors of rat.

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12 December 2020

Brain tumors induced in dogs by the Schmidt-Ruppin strain of Rous sarcoma virus. Neuropathological and immunological observations

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12 December 2020

Establishment of a brain-tumor model in adult monkeys.

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12 December 2020

Macrophages in experimental and human brain tumors. Part 1: Studies of the macrophage content of experimental rat brain tumors of varying immunogenicity

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12 December 2020

Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors

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12 December 2020

MRI characterization of 9L-glioma in rat brain at 4.7 Tesla

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12 December 2020

The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats

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12 December 2020

In vivo transfer of the human interleukin-2 gene: negative tumoricidal results in experimental brain tumors.

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12 December 2020

Combination of radiation therapy and intracranial bleomycin in the 9L rat brain tumor model

1 reference

12 December 2020

Boron neutron capture therapy of brain tumors: enhanced survival following intracarotid injection of sodium borocaptate with or without blood-brain barrier disruption.

1 reference

12 December 2020

SELECTIVE INDUCTION OF MALIGNANT TUMORS IN THE BRAIN AND SPINAL CORD OF RATS BY N-METHYL-N-NITROSOUREA

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12 December 2020

A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats

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12 December 2020

Quantitative diffusion MR imaging of cerebral tumor and edema

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12 December 2020

Synthesis by a clonal line of rat glial cells of a protein unique to the nervous system

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12 December 2020

Immunity to transplantable nitrosourea-induced neurogenic tumors. II. Immunoprophylaxis of tumors of the brain

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12 December 2020

The effect of hyperosmotic blood-brain barrier disruption on blood-to-tissue transport in ENU-induced gliomas

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12 December 2020

Selective ablation of rat brain tumors by boron neutron capture therapy.

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12 December 2020

Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascin

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12 December 2020

Production of stable phenotypes from 9L rat brain tumor multicellular spheroids treated with 1,3-bis(2-chloroethyl)-1-nitrosourea

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12 December 2020

Targeting anticancer drugs to the brain: II. Physiological pharmacokinetic model of oxantrazole following intraarterial administration to rat glioma-2 (RG-2) bearing rats.

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12 December 2020

Effect of herpes simplex virus thymidine kinase expression levels on ganciclovir-mediated cytotoxicity and the "bystander effect".

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12 December 2020

Quantitative aspects of transplantation of experimentally induced tumors of the nervous system

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12 December 2020

High resolution quantitative relaxation and diffusion MRI of three different experimental brain tumors in rat.

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12 December 2020

Phenotype and functional activity of tumor-infiltrating lymphocytes isolated from immunogenic and nonimmunogenic rat brain tumors

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12 December 2020

Differential retention of rhodamine 123 by avian sarcoma virus-induced glioma and normal brain tissue of the rat in vivo

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12 December 2020

Morphological and immunochemical studies of rat glial tumors and clonal strains propagated in culture

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12 December 2020

Thymidine kinase-mediated killing of rat brain tumors

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12 December 2020

Comparative permeability of different glioma models to horseradish peroxidase

1 reference

12 December 2020

The 9L rat brain tumor: Description and application of an animal model

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12 December 2020

An improved rat brain-tumor model.

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12 December 2020

Herpes simplex virus thymidine kinase gene therapy for rat malignant brain tumors

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12 December 2020

Control of intracerebral gliosarcomas in rats by boron neutron capture therapy with p-boronophenylalanine

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12 December 2020

Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors

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12 December 2020

Identifiers

DOI

10.1023/A:1005805203044

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PubMed ID

9525831

Dimensions Publication ID

26 September 2017

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1 reference

PubMed ID

9525831