(Q41085755)

English

Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor.

scientific article published on October 1997

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Jennifer E Rowland

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

S N Behncken

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

S W Rowlinson

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

B L Conway-Campbell

4

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6 November 2019

T A Monks

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

M J Waters

6

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6 November 2019

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publication date

1 October 1997

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6 November 2019

Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

272

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6 November 2019

43

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6 November 2019

27077-27083

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Binding in the growth hormone receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

A hot spot of binding energy in a hormone-receptor interface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Rational design of receptor-specific variants of human growth hormone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Reduced 125I-hGH binding by serum of dwarf pigs but not by serum of dwarfed poodles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

The first disulphide loop of the rabbit growth hormone receptor is required for binding to the hormone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

A single arginine residue determines species specificity of the human growth hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

A growth hormone agonist produced by targeted mutagenesis at binding site 1. Evidence that site 1 regulates bioactivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Rational design of potent antagonists to the human growth hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Structural features of prolactins and growth hormones that can be related to their biological properties

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Potentiation of the somatogenic and lactogenic activity of human growth hormone with monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Brief report: short stature caused by a mutant growth hormone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Evidence for Involvement of the Carboxy Terminus of Helix 1 of Growth Hormone in Receptor Binding: Use of Charge Reversal Mutagenesis to Account for Calcium Dependence of Binding and for Design of Higher Affinity Analogs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Comparison of a structural and a functional epitope

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.43.27077

21 January 2018

Identifiers

10.1074/JBC.272.43.27077

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9341147%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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