(Q41090386)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

review article

1 reference

title

Analysis of gene function in lymphocytes by RAG-2-deficient blastocyst complementation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

author name string

Chen J

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

publication date

1 January 1996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

published in

Advances in Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

volume

62

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

page(s)

31-59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781266%20AND%20SRC:MED&resulttype=core&format=json

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

18 October 2019

cites work

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Gene targeting in embryonic stem cells

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7 January 2021

Gene targeting and its application to the study of B-cell development

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7 January 2021

T-cell development and function in gene-knockout mice

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7 January 2021

Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene

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7 January 2021

Effects of an Rb mutation in the mouse

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7 January 2021

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

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7 January 2021

Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice

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7 January 2021

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

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7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

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7 January 2021

V(D)J recombination: molecular biology and regulation

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

c-Jun is essential for normal mouse development and hepatogenesis

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7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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7 January 2021

An early haematopoietic defect in mice lacking the transcription factor GATA-2

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7 January 2021

Generation of normal lymphocyte populations by Rb-deficient embryonic stem cells

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7 January 2021

Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells

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7 January 2021

Essential role for ZAP-70 in both positive and negative selection of thymocytes

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7 January 2021

Production of homozygous mutant ES cells with a single targeting construct

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7 January 2021

A mutant neomycin phosphotransferase II gene reduces the resistance of transformants to antibiotic selection pressure

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7 January 2021

Double targeted gene replacement for creating null mutants

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7 January 2021

Bclx regulates the survival of double-positive thymocytes

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7 January 2021

Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

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7 January 2021

Recombinase-mediated gene activation and site-specific integration in mammalian cells

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7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

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7 January 2021

Shutdown of class switch recombination by deletion of a switch region control element.

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7 January 2021

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus

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7 January 2021

Control points in early T-cell development

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7 January 2021

A role for a pre-T-cell receptor in T-cell development

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7 January 2021

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

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7 January 2021

Molecular and biological characterization of a murine ligand for CD40

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7 January 2021

Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50

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7 January 2021

Isolation and characterization of human tonsil dendritic cells

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7 January 2021

The CD40 antigen and its ligand

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7 January 2021

CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.

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7 January 2021

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

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7 January 2021

Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21).

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7 January 2021

The CD19/CD21 signal transduction complex of B lymphocytes

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7 January 2021

CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

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7 January 2021

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

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7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

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7 January 2021

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

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7 January 2021

Regulation of lymphocyte function by protein phosphorylation

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7 January 2021

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

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7 January 2021

Control of lymphopoiesis by p50csk, a regulatory protein tyrosine kinase

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7 January 2021

Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells

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7 January 2021

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

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7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

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7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

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7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

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7 January 2021

Stimulation of p21 ras upon T-cell activation

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7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

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7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

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7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

1 reference

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7 January 2021

The structure and regulation of protein phosphatases

1 reference

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7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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7 January 2021

T cell responses in calcineurin A alpha-deficient mice

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7 January 2021

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

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7 January 2021

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

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7 January 2021

Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes

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7 January 2021

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

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7 January 2021

Defective B cell development and function in Btk-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960427-7

7 January 2021

Impaired expansion of mouse B cell progenitors lacking Btk.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960427-7

7 January 2021

Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer

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https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960427-7

7 January 2021

Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins

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7 January 2021

Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene

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7 January 2021

Defective activation and survival of T cells lacking the Ets-1 transcription factor

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7 January 2021

The mechanism of action of cyclosporin A and FK506

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7 January 2021

Development of the primary antibody repertoire

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7 January 2021

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene.

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7 January 2021

A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

1 reference

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7 January 2021

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

1 reference

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7 January 2021

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960427-7

7 January 2021

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

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7 January 2021

Switch transcripts in immunoglobulin class switching

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7 January 2021

A lymphocyte-specific enhancer in the mouse immunoglobulin kappa gene.

1 reference

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7 January 2021

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions

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7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960427-7

7 January 2021

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

1 reference

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7 January 2021

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1 reference

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7 January 2021

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2808%2960427-7

7 January 2021

10.1016/S0065-2776(08)60427-7

Identifiers

DOI

0 references

1 reference