(Q41112024)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Looking for protein stabilizing drugs with thermal shift assay (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Maria Monticelli

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Maria Vittoria Cubellis

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Giuseppina Andreotti

1

1 reference

PubMed ID

25845367

26 September 2017

Maria Monticelli

2

1 reference

PubMed ID

25845367

26 September 2017

Maria Vittoria Cubellis

3

1 reference

26 September 2017

5 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

Drug Testing and Analysis

4 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

7

1 reference

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4 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

831-834

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

Loss of protein structure stability as a major causative factor in monogenic disease.

4 March 2020

cites work

1 reference

Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics

21 January 2018

1 reference

Fabry_CEP: a tool to identify Fabry mutations responsive to pharmacological chaperones.

21 January 2018

1 reference

A chaperone enhances blood α-glucosidase activity in Pompe disease patients treated with enzyme replacement therapy.

21 January 2018

1 reference

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination

21 January 2018

1 reference

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

21 January 2018

1 reference

Thermofluor-based high-throughput stability optimization of proteins for structural studies

21 January 2018

1 reference

High-density miniaturized thermal shift assays as a general strategy for drug discovery

21 January 2018

1 reference

Thermodynamic stability of carbonic anhydrase: measurements of binding affinity and stoichiometry using ThermoFluor.

21 January 2018

1 reference

Biochemical phenotype of a common disease-causing mutation and a possible therapeutic approach for the phosphomannomutase 2-associated disorder of glycosylation

21 January 2018

1 reference

Conformational response to ligand binding in phosphomannomutase2: insights into inborn glycosylation disorder.

21 January 2018

1 reference

Co-administration with the pharmacological chaperone AT1001 increases recombinant human α-galactosidase A tissue uptake and improves substrate reduction in Fabry mice

21 January 2018

1 reference

Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability

21 January 2018

1 reference

The Molecular Basis of Pharmacological Chaperoning in Human α-Galactosidase

21 January 2018

1 reference

The pharmacological chaperone 1-deoxynojirimycin increases the activity and lysosomal trafficking of multiple mutant forms of acid alpha-glucosidase

21 January 2018

1 reference

Molecular interaction of imino sugars with human alpha-galactosidase: Insight into the mechanism of complex formation and pharmacological chaperone action in Fabry disease

21 January 2018

1 reference

A thermodynamic assay to test pharmacological chaperones for Fabry disease.

21 January 2018

1 reference

2-(3-Oxo-1,3-diphenylpropyl)malonic Acids as Potent Allosteric Ligands of the PIF Pocket of Phosphoinositide-Dependent Kinase-1: Development and Prodrug Concept

21 January 2018

1 reference

Analysis of protein stability and ligand interactions by thermal shift assay

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25845367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/DTA.1798

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25845367%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference