(Q41122179)

14 June 2018

title

Intragenic Tsc2 somatic mutations as Knudson's second hit in spontaneous and chemically induced renal carcinomas in the Eker rat model (English)

1 reference

14 June 2018

author name string

T Kobayashi

1

1 reference

14 June 2018

S Urakami

2

1 reference

14 June 2018

Y Hirayama

3

1 reference

14 June 2018

T Yamamoto

4

1 reference

14 June 2018

M Nishizawa

5

1 reference

14 June 2018

T Takahara

6

1 reference

14 June 2018

Y Kubo

7

1 reference

14 June 2018

O Hino

8

1 reference

14 June 2018

publication date

1 March 1997

1 reference

14 June 2018

number of pages

8

1 reference

Japanese Journal of Cancer Research

inferred from page(s)

published in

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14 June 2018

volume

88

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14 June 2018

issue

3

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14 June 2018

page(s)

254-261

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14 June 2018

Identification of a nonsense mutation at the 5' end of the TSC2 gene in a family with a presumptive diagnosis of tuberous sclerosis complex

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Mutation analysis of the TSC2 gene in an African-American family

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Presence of potent transcriptional activation domains in the predisposing tuberous sclerosis (Tsc2) gene product of the Eker rat model

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Identification and characterization of the tuberous sclerosis gene on chromosome 16

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Genetic predisposition to transplacentally induced renal cell carcinomas in the Eker rat.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

p53 gene mutations in human skin cancers and precancerous lesions: comparison with immunohistochemical analysis

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Early detection of Knudson's two-hits in preneoplastic renal cells of the Eker rat model by the laser microdissection procedure

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Allelic Loss at the Tuberous Sclerosis (Tsc2) Gene Locus in Spontaneous Uterine Leiomyosarcomas and Pituitary Adenomas in the Eker Rat Model

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Loss of heterozygosity in the tuberous sclerosis (TSC2) region of chromosome band 16p13 occurs in sporadic as well as TSC-associated renal angiomyolipomas

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

DNA methylation errors and cancer.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Expression and differential splicing of the mouse TSC2 homolog.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Novel mutations detected in the TSC2 gene from both sporadic and familial TSC patients.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

A de novo frame-shift mutation in the tuberin gene

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5921374

Mutation and cancer: statistical study of retinoblastoma

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1349-7006.1997.TB00375.X

A novel cancer predisposition syndrome in the Eker rat model

21 January 2018

1 reference

12 December 2020

Allelic loss at the predisposing gene locus in spontaneous and chemically induced renal cell carcinomas in the Eker rat

1 reference

12 December 2020

A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer

1 reference

12 December 2020

Renal carcinogenesis in the Eker rat

1 reference

12 December 2020

The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene

1 reference

12 December 2020

Suppression of the neoplastic phenotype by replacement of the Tsc2 gene in Eker rat renal carcinoma cells

1 reference

12 December 2020

10.1111/J.1349-7006.1997.TB00375.X

Identifiers

DOI

1 reference

14 June 2018

PMCID

5921374

1 reference

14 June 2018

PubMed ID

9140109

1 reference

14 June 2018