(Q41127730)

English

Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin

scientific article published on April 2006

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scholarly article

1 reference

Europe PubMed Central

27 September 2017

Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin (English)

1 reference

Europe PubMed Central

27 September 2017

molecular chaperones

0 references

author name string

Ashis Biswas

1

1 reference

Europe PubMed Central

27 September 2017

Antonia Miller

2

1 reference

Europe PubMed Central

27 September 2017

Tomoko Oya-Ito

3

1 reference

Europe PubMed Central

27 September 2017

Puttur Santhoshkumar

4

1 reference

Europe PubMed Central

27 September 2017

Manjunatha Bhat

5

1 reference

Europe PubMed Central

27 September 2017

Ram H Nagaraj

6

1 reference

Europe PubMed Central

27 September 2017

language of work or name

0 references

publication date

1 April 2006

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

45

1 reference

Europe PubMed Central

27 September 2017

14

1 reference

Europe PubMed Central

27 September 2017

4569-4577

1 reference

Europe PubMed Central

27 September 2017

Ageing and vision: structure, stability and function of lens crystallins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Deamidation affects structural and functional properties of human alphaA-crystallin and its oligomerization with alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Alpha-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

A positive charge preservation at position 116 of alpha A-crystallin is critical for its structural and functional integrity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Phe71 is essential for chaperone-like function in alpha A-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Correlation between the loss of the chaperone-like activity and the oxidation, isomerization and racemization of gamma-irradiated alpha-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

The role of AGEs in aging: causation or correlation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Phosphorylation-induced change of the oligomerization state of alpha B-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Protein crosslinking by the Maillard reaction: dicarbonyl-derived imidazolium crosslinks in aging and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Alpha-crystallin as a molecular chaperone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

ATP-enhanced molecular chaperone functions of the small heat shock protein human alphaB crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Conformational and functional differences between recombinant human lens alphaA- and alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

New biomarkers of Maillard reaction damage to proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Evolution of the alpha-crystallin/small heat-shock protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

The glyoxalase system in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

The chaperone activity of bovine alpha crystallin. Interaction with other lens crystallins in native and denatured states.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Alpha-crystallin can function as a molecular chaperone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

27 September 2017

Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: physiological significance and caveats of in vitro aggregation assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

14 June 2018

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

14 June 2018

Genealogy of the alpha-crystallin--small heat-shock protein superfamily.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

14 June 2018

Methylglyoxal concentration and glyoxalase activities in the human lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

14 June 2018

α-Crystallin. The isolation and characterization of distinct macromolecular fractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

14 June 2018

Recognition sequence 2 (residues 60-71) plays a role in oligomerization and exchange dynamics of alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Insights into hydrophobicity and the chaperone-like function of alphaA- and alphaB-crystallins: an isothermal titration calorimetric study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

The IXI/V motif in the C-terminal extension of alpha-crystallins: alternative interactions and oligomeric assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Relationship between chaperone activity and oligomeric size of recombinant human alphaA- and alphaB-crystallin: a tryptic digestion study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Role of ATP on the interaction of alpha-crystallin with its substrates and its implications for the molecular chaperone function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Role of the conserved SRLFDQFFG region of alpha-crystallin, a small heat shock protein. Effect on oligomeric size, subunit exchange, and chaperone-like activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Distinct roles of alphaA- and alphaB-crystallins under thermal and UV stresses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Evaluation of hydrophobicity versus chaperonelike activity of bovine alphaA- and alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Substituted hydrophobic and hydrophilic residues at methionine-68 influence the chaperone-like function of alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Argpyrimidine, a blue fluorophore in human lens proteins: high levels in brunescent cataractous lenses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Decreased molecular chaperone property of alpha-crystallins due to posttranslational modifications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Estimation of globular protein secondary structure from circular dichroism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597574

19 August 2018

Modified alpha A crystallin in the retina: altered expression and truncation with aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescent probes for conformational states of proteins. I. Mechanism of fluorescence of 2-p-toluidinylnaphthalene-6-sulfonate, a hydrophobic probe

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature-dependent chaperone activity and structural properties of human alphaA- and alphaB-crystallins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-crystallin prevents irreversible protein denaturation and acts cooperatively with other heat-shock proteins to renature the stabilized partially denatured protein in an ATP-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature dependent chaperone-like activity of alpha-crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temperature-induced exposure of hydrophobic surfaces and its effect on the chaperone activity of alpha-crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presence of a glucose-derived Maillard reaction product in the human lens

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of some post-translational modifications on the chaperone-like activity of alpha-crystallin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein modification by methylglyoxal: chemical nature and synthetic mechanism of a major fluorescent adduct

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of chaperone alpha-crystallin with the molten globule state of xylose reductase. Implications for reconstitution of the active enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-crystallin does not require temperature activation for its chaperone-like activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional consequences of the mutation of a conserved arginine residue in alphaA and alphaB crystallins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16584192

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI052574S

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

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