(Q41128220)

English

Epidermal growth factor receptor signaling cascade as target for tyrphostin (RG 50864) in epithelial cells. Paradoxical effects on mitogen-activated protein kinase kinase and mitogen-activated protein kinase activities

scientific article published on February 1997

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 September 2017

Epidermal growth factor receptor signaling cascade as target for tyrphostin (RG 50864) in epithelial cells. Paradoxical effects on mitogen-activated protein kinase kinase and mitogen-activated protein kinase activities (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

author name string

F Nowak

1

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

A Jacquemin-Sablon

2

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Europe PubMed Central

PubMed publication ID

27 September 2017

J Pierre

3

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Europe PubMed Central

PubMed publication ID

27 September 2017

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publication date

1 February 1997

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PubMed publication ID

27 September 2017

Biochemical Pharmacology

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Europe PubMed Central

PubMed publication ID

27 September 2017

53

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Europe PubMed Central

PubMed publication ID

27 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

287-298

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

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Transformation of NIH 3T3 cells by overexpression of the normal coding sequence of the rat neu gene.

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The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers

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Tyrphostins inhibit the epidermal growth factor receptor-mediated breakdown of phosphoinositides

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EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

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Rapid uptake of tyrphostin into A431 human epidermoid cells is followed by delayed inhibition of epidermal growth factor (EGF)-stimulated EGF receptor tyrosine kinase activity

1 reference

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Activation of the mitogen-activated protein kinase cascade by tyrphostin (RG 50864).

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Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

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The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

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Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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7 January 2021

Identifiers

10.1016/S0006-2952(96)00688-0

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

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