(Q41132577)

English

Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12.

scientific article published on 5 April 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12. (English)

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

immunosuppression

1 reference

based on heuristic

inferred from title

author name string

Mariana Malvicini

1

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Mariana Ingolotti

2

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Flavia Piccioni

3

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Mariana Garcia

4

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Juan Bayo

5

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Catalina Atorrasagasti

6

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Laura Alaniz

7

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Jorge B Aquino

8

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Jaime A Espinoza

9

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Manuel Gidekel

10

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

O Graciela Scharovsky

11

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Pablo Matar

12

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Guillermo Mazzolini

13

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

5 April 2011

1 reference

Europe PubMed Central

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27 September 2017

Molecular Oncology

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

242-255

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts

1 reference

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Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained

1 reference

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27 September 2017

Targeted immunotherapy for colorectal cancer: monoclonal antibodies and immunotoxins

1 reference

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27 September 2017

Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Myeloid-derived suppressor cells as regulators of the immune system

1 reference

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27 September 2017

Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response.

1 reference

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27 September 2017

Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of cancer.

1 reference

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27 September 2017

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

How regulatory T cells work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

1 reference

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27 September 2017

EBV latent membrane proteins (LMPs) 1 and 2 as immunotherapeutic targets: LMP-specific CD4+ cytotoxic T cell recognition of EBV-transformed B cell lines.

1 reference

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27 September 2017

Immunotherapy and immunoescape in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Immunosuppressive strategies that are mediated by tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Regulatory T cells in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Regulatory T cells, tumour immunity and immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

How do CD4+CD25+ regulatory T cells control autoimmunity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Immunosuppressive networks in the tumour environment and their therapeutic relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Interleukin-12 and the regulation of innate resistance and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Chemo-immunotherapy and chemo-adoptive immunotherapy of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Surgical resection of liver metastases of colorectal carcinoma: short and long-term results.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

An overview of cyclophosphamide development and clinical applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

27 September 2017

Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

17 June 2018

A novel synergistic combination of cyclophosphamide and gene transfer of interleukin-12 eradicates colorectal carcinoma in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

Gene therapy of cancer with interleukin-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

IL-12 gene therapy for cancer: in synergy with other immunotherapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

Large nontransplanted hepatocellular carcinoma in woodchucks: treatment with adenovirus-mediated delivery of interleukin 12/B7.1 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528288

19 August 2018

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2011.03.007

21 January 2018

Eradication of medullary multiple myeloma by CD4+ cytotoxic human T lymphocytes directed at a single minor histocompatibility antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CD4(+) CTLs ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th2/Th1 switch induced by a single low dose of cyclophosphamide in a rat metastatic lymphoma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoablative high-dose cyclophosphamide without stem-cell rescue for refractory, severe autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-derived CD4(+)CD25(+) regulatory T cell suppression of dendritic cell function involves TGF-beta and IL-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21515097

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLONC.2011.03.007

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

ResearchGate publication ID

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