(Q41135209)

27 September 2017

title

The tumor suppressor p53 modifies mutational processes in a human lymphoblastoid cell line (English)

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27 September 2017

Xia F

1

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27 September 2017

Liber HL

series ordinal

2

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27 September 2017

language of work or name

English

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publication date

1 January 1997

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27 September 2017

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27 September 2017

volume

373

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27 September 2017

issue

1

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27 September 2017

page(s)

87-97

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A comparison of induced mutation at homologous alleles of the tk locus in human cells. II. Molecular analysis of mutants

27 September 2017

cites work

1 reference

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Different cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid cell lines derived from a single donor

7 January 2021

1 reference

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

7 January 2021

1 reference

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p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

7 January 2021

1 reference

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

7 January 2021

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Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

7 January 2021

1 reference

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 January 2021

1 reference

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Presence of a potent transcription activating sequence in the p53 protein

7 January 2021

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Inverted DNA repeats: a source of eukaryotic genomic instability

7 January 2021

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The dominating effect of mutant p53

7 January 2021

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p53 mutations in human cancers

7 January 2021

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Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

7 January 2021

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Vectors used for expression in mammalian cells

7 January 2021

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

7 January 2021

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Cancer. p53, guardian of the genome

7 January 2021

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A comparison of mutation induction at the tk and hprt loci in human lymphoblastoid cells; quantitative differences are due to an additional class of mutations at the autosomal tk locus.

7 January 2021

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Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies

7 January 2021

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Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status

7 January 2021

1 reference

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Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

7 January 2021

1 reference

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p53 is required for radiation-induced apoptosis in mouse thymocytes

7 January 2021

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Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

7 January 2021

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High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia

7 January 2021

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A role for genomic instability in cellular radioresistance?

7 January 2021

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Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break

7 January 2021

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DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

7 January 2021

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Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

7 January 2021

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Spectra of spontaneous and X-ray-induced mutations at the hprt locus in related human lymphoblast cell lines that express wild-type or mutant p53.

7 January 2021

1 reference

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Sequence-specific transcriptional activation is essential for growth suppression by p53.

7 January 2021

1 reference

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p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines

7 January 2021

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Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

7 January 2021

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p53 deficiency does not affect the accumulation of point mutations in a transgene target

7 January 2021

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The nuclear tyrosine kinase c-Abl negatively regulates cell growth

7 January 2021

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Different sensitivity to cell killing and chromosome mutation induction by gamma rays in two human lymphoblastoid cell lines derived from a single donor: possible role of apoptosis

7 January 2021

1 reference

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

7 January 2021

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Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

7 January 2021

1 reference

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Genomic instability due to germline p53 mutations drives preneoplastic Progression toward cancer in human cells

7 January 2021

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Microsatellite instability in cancer of the proximal colon

7 January 2021

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Genomic instability and cancer

7 January 2021

1 reference

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An evolutionary perspective on apoptosis.

7 January 2021

1 reference

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Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

7 January 2021

1 reference

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p53 modulation of TFIIH-associated nucleotide excision repair activity

7 January 2021

1 reference

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Electroporation of human lymphoblastoid cells

7 January 2021

1 reference

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Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900193-5

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900193-5

Induction of p53 in mouse cells decreases mutagenesis by UV radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900193-5

The relative radiosensitivity of TK6 and WI-L2-NS lymphoblastoid cells derived from a common source is primarily determined by their p53 mutational status

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900193-5

10.1016/S0027-5107(96)00193-5

7 January 2021

Identifiers

DOI

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27 September 2017

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