(Q41135854)

English

Phenotypic debrisoquine 4-hydroxylase activity among extensive metabolizers is unrelated to genotype as determined by the Xba-I restriction fragment length polymorphism

scientific article published on September 1, 1991

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1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Phenotypic debrisoquine 4-hydroxylase activity among extensive metabolizers is unrelated to genotype as determined by the Xba-I restriction fragment length polymorphism (English)

1 reference

10.1111/J.1365-2125.1991.TB03900.X

https://api.crossref.org/works/10.1111/J.1365-2125.1991.TB03900.X

29 October 2022

restriction fragment length polymorphism

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

1 reference

10.1111/J.1365-2125.1991.TB03900.X

https://api.crossref.org/works/10.1111/J.1365-2125.1991.TB03900.X

29 October 2022

author name string

J. Turgeon

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

W. E. Evans

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

M. V. Relling

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

G. R. Wilkinson

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

D. M. Roden

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

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publication date

1 September 1991

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

full work available at URL

https://europepmc.org/articles/PMC1368519

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

https://europepmc.org/articles/PMC1368519?pdf=render

Portable Document Format

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Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1685663

29 October 2022

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2125.1991.tb03900.x

1 reference

10.1111/J.1365-2125.1991.TB03900.X

https://api.crossref.org/works/10.1111/J.1365-2125.1991.TB03900.X

29 October 2022

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.1991.tb03900.x/fullpdf

1 reference

10.1111/J.1365-2125.1991.TB03900.X

https://api.crossref.org/works/10.1111/J.1365-2125.1991.TB03900.X

29 October 2022

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

32

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

283-288

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

The polymorphic oxidation of beta-adrenoceptor antagonists. Clinical pharmacokinetic considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism--hypothesis testing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism--histograms and probit plots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

Polymorphisms of Oxidation at Carbon Centers of Drugs and Their Clinical Significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

Polymorphic hydroxylation of Debrisoquine in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

The distribution of debrisoquine metabolic phenotypes and implications for the suggested association with lung cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

27 September 2017

Polymorphic drug oxidation: pharmacokinetic basis and comparison of experimental indices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

14 June 2018

Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

14 June 2018

Oxidative metabolism of encainide: polymorphism, pharmacokinetics and clinical considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

14 June 2018

Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

14 June 2018

Pharmacokinetic profile of encainide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

14 June 2018

Disposition kinetics of encainide and metabolites

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1991.TB03900.X

21 January 2018

Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1991.TB03900.X

21 January 2018

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1991.TB03900.X

21 January 2018

Lung cancer risk, occupational exposure, and the debrisoquine metabolic phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1368519

2 December 2018

Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiarrhythmic activity, electrocardiographic effects and pharmacokinetics of the encainide metabolites O-desmethyl encainide and 3-methoxy-O-desmethyl encainide in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-inheritance of the polymorphic metabolism of encainide and debrisoquin

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered distribution of debrisoquine oxidation phenotypes in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debrisoquine/sparteine-type polymorphism of drug oxidation. Purification and characterization of two functionally different human liver cytochrome P-450 isozymes involved in impaired hydroxylation of the prototype substrate bufuralol

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xbal 16- plus 9-kilobase DNA restriction fragments identify a mutant allele for debrisoquin hydroxylase: report of a family study

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of genetic polymorphism on the metabolism and disposition of encainide in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/1685663

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.1991.TB03900.X

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

ResearchGate publication ID

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