(Q41137398)

27 September 2017

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title

Alternatives to the 2-species bioassay for the identification of potential human carcinogens (English)

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27 September 2017

J Ashby

1

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27 September 2017

publication date

1 March 1996

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Human & Experimental Toxicology

27 September 2017

published in

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27 September 2017

volume

15

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27 September 2017

issue

3

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27 September 2017

page(s)

183-202

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Too many rodent carcinogens: mitogenesis increases mutagenesis

27 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

International Commission for Protection Against Environmental Mutagens and Carcinogens. Two million rodent carcinogens? The role of SAR and QSAR in their detection

21 January 2018

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Prediction of rodent carcinogenicity for 44 chemicals: results.

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Nucleophilic selectivity of carcinogens as a determinant of enhanced mutational response in excision repair-defective strains in Drosophila: effects of 30 carcinogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Classification according to chemical structure, mutagenicity to Salmonella and level of carcinogenicity of a further 39 chemicals tested for carcinogenicity by the U.S. National Toxicology Program

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposures

21 January 2018

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DNA adducts of chemical carcinogens

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

International Commission for Protection Against Environmental Mutagens and Carcinogens. Application of SAR methods to non-congeneric data bases associated with carcinogenicity and mutagenicity: issues and approaches

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Mechanistic relationship among mutagenicity, skin sensitization, and skin carcinogenicity

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

21 January 2018

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Carcinogenicity evaluations and ongoing studies: the IARC databases

21 January 2018

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The genetic toxicity of human carcinogens and its implications

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

The prospects for a simplified and internationally harmonized approach to the detection of possible human carcinogens and mutagens

21 January 2018

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Mutation, cancer and transgenic models: relevance to the toxicology industry

21 January 2018

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Transgenic animal models for measuring mutations in vivo

21 January 2018

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A preliminary evaluation of the performance of the Muta Mouse (lacZ) and Big Blue (lacI) transgenic mouse mutation assays

21 January 2018

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Dose-ranging and dose-setting for in vivo genetic toxicology studies

21 January 2018

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Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals

21 January 2018

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Detection of genotoxic effects in human gastric and nasal mucosa cells isolated from biopsy samples.

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids

21 January 2018

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Alpha 2u-globulin nephropathy: review of the cellular and molecular mechanisms involved and their implications for human risk assessment

21 January 2018

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Risk assessment of d-limonene: an example of male rat-specific renal tumorigens.

21 January 2018

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Consideration of both genotoxic and nongenotoxic mechanisms in predicting carcinogenic potential

21 January 2018

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Measurement of nuclear DNA modification by 32P-postlabeling in the kidneys of male and female Fischer 344 rats after multiple gavage doses of hydroquinone.

21 January 2018

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The relationship between use of the maximum tolerated dose and study sensitivity for detecting rodent carcinogenicity.

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Relevance of maximum tolerated dose to human carcinogenic risk

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Decreased electrophilicity of chemicals carcinogenic only at the maximum tolerated dose

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Interspecies extrapolation in carcinogenesis: prediction between rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Benzyl acetate: from mutagenic carcinogen to non-mutagenic non-carcinogenic in 7 years?

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Use of a multistrain assay could improve the NTP carcinogenesis bioassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Chemicals for evaluating the sensitivity and specificity of reduced/transgenic rodent cancer bioassay protocols

21 January 2018

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https://api.crossref.org/works/10.1177%2F096032719601500301

Will all chemicals be carcinogenic to rodents when adequately evaluated?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Potential role of alpha-2 mu-globulin, protein droplet accumulation, and cell replication in the renal carcinogenicity of rats exposed to trichloroethylene, perchloroethylene, and pentachloroethane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Induction of hepatic mutations in lacI transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Detection of human carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

Change the rules for food additives

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F096032719601500301

10.1177/096032719601500301

21 January 2018

Identifiers

DOI

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1 reference