(Q41151657)

English

Molecular analysis of lacI mutations in Rat2 cells exposed to 7,12-dimethylbenz[a]anthracene: evidence for DNA sequence and DNA strand biases for mutation

scientific article published on November 1996

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scholarly article

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Europe PubMed Central

27 September 2017

Molecular analysis of lacI mutations in Rat2 cells exposed to 7,12-dimethylbenz[a]anthracene: evidence for DNA sequence and DNA strand biases for mutation (English)

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Europe PubMed Central

27 September 2017

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author name string

Manjanatha MG

1

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Europe PubMed Central

27 September 2017

Chen JB

2

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Europe PubMed Central

27 September 2017

Shaddock JG Jr

3

1 reference

Europe PubMed Central

27 September 2017

Harris AJ

4

1 reference

Europe PubMed Central

27 September 2017

Shelton SD

5

1 reference

Europe PubMed Central

27 September 2017

Casciano DA

6

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Europe PubMed Central

27 September 2017

language of work or name

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publication date

1 November 1996

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Europe PubMed Central

27 September 2017

Mutation Research

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Europe PubMed Central

27 September 2017

372

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Europe PubMed Central

27 September 2017

53-64

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Europe PubMed Central

27 September 2017

1

1 reference

Europe PubMed Central

27 September 2017

Revised methods for the Salmonella mutagenicity test

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Forward mutations to arabinose resistance in Salmonella typhimurium strains: a sensitive assay for mutagenicity testing

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The dose-response relationship for ethyl methanesulfonate-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells

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Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system

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Mutagenesis by chemical agents in V79 chinese hamster cells: a review and analysis of the literature. A report of the Gene-Tox Program

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Mutation assay at the thymidine kinase locus in diploid human lymphoblasts

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Development of a rat cell line containing stably integrated copies of a lambda/lacI shuttle vector

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The use of shuttle vectors for mutation analysis in transgenic mice and rats.

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Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression.

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A direct mechanism of mammary carcinogenesis induced by 7,12-dimethyl-benz(alpha)anthracene.

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Effects of progesterone on mammary carcinogenesis when various doses of DMBA were applied directly to rat mammae

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Carcinogenic responses to chemicals applied directly to rat mammary glands in situ.

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Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and rat mammary gland

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7 January 2021

Lymphocyte mutant frequency in relation to DNA adduct formation in rats treated with tumorigenic doses of the mammary gland carcinogen 7,12-dimethylbenz[a]anthracene

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Effect of pretreatment with hepatic mixed-function oxidase inducers on the genotoxicity of four rat carcinogens in the hepatocyte/DNA repair assay

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Lambda ZAP: a bacteriophage lambda expression vector with in vivo excision properties

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Big Blue transgenic mouse lacI mutation analysis.

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How lac Repressor Binds to DNA

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Statistical test for the comparison of samples from mutational spectra

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Computer program for the analysis of mutational spectra: application to p53 mutations.

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7 January 2021

Mechanisms of spontaneous mutagenesis: an analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene.

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Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene.

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7 January 2021

Mutational spectra in the lacl gene in skin from 7,12-dimethylbenz[a]anthracene-treated and untreated transgenic mice.

1 reference

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7 January 2021

Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacl shuttle vector

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7 January 2021

Evidence for the involvement of a diol-epoxide in the binding of 7,12-dimethylbenz(a)anthracene to DNA in cells in culture

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7 January 2021

A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA.

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7 January 2021

DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells

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7 January 2021

Molecular analysis of DNA adducts and hprt mutations produced by 6-nitrosochrysene in Chinese hamster ovary cells.

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7 January 2021

Trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene is metabolized to form a major adduct with deoxyguanosine and produces mutations in the hprt gene of Chinese hamster ovary cells at G:C basepairs.

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7 January 2021

Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells.

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7 January 2021

Molecular analysis of ultraviolet-induced mutations in a xeroderma pigmentosum cell line

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7 January 2021

Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cells

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DNA strand specificity for UV-induced mutations in mammalian cells

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7 January 2021

DNA sequence analysis of hprt mutations in lymphocytes from Sprague-Dawley rats treated with 7,12-dimethylbenz[a]anthracene.

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Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA.

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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

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Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

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7 January 2021

Tissue-specific activating mutations of Ha- and Ki-ras oncogenes in skin, lung, and liver tumors induced in mice following transplacental exposure to DMBA.

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7 January 2021

Epidermal papillomas and carcinomas induced in uninitiated mouse skin by tumor promoters alone contain a point mutation in the 61st codon of the Ha-ras oncogene

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H- and K-ras mutational profiles in chemically induced liver tumors from B6C3F1 and CD-1 mice

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Sequence of the lacI gene

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Oncogene activation in chemical carcinogenesis

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10.1016/S0027-5107(96)00162-5

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

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