(Q41153250)

27 September 2017

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title

Signals controlling the expression of PDGF. (English)

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27 September 2017

R P Dirks

1

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PubMed ID

8858568

27 September 2017

H P Bloemers

series ordinal

2

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27 September 2017

1 January 1995

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Molecular Biology Reports

27 September 2017

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27 September 2017

22

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27 September 2017

1-24

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27 September 2017

1

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https://scigraph.springernature.com/pub.10.1007/bf00996300

27 September 2017

0 references

cites work

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cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules

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Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins

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Expression of recombinant platelet-derived growth factor A- and B-chain homodimers in rat-1 cells and human fibroblasts reveals differences in protein processing and autocrine effects

21 January 2018

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Regulation of platelet-derived growth factor ligand and receptor gene expression by alpha-thrombin in vascular smooth muscle cells

21 January 2018

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Phorbol ester induces c-sis gene transcription in stem cell line K-562.

21 January 2018

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Dexamethasone-induced increase in platelet-derived growth factor (B) mRNA in human alveolar macrophages and myelomonocytic HL60 macrophage-like cells

21 January 2018

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Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines

21 January 2018

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Role for platelet-derived growth factor-like and epidermal growth factor-like signaling pathways in gastrulation and spiculogenesis in the Lytechinus sea urchin embryo.

21 January 2018

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Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryo

21 January 2018

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Differential regulation of the genes encoding platelet-derived growth factor receptor and its ligand in rat lung during microvascular and alveolar wall remodeling in hyperoxia

21 January 2018

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Coexpression of platelet-derived growth factor (PDGF) A-chain and PDGF receptor genes in human gastric carcinomas.

21 January 2018

1 reference

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Induction of fos and sis proto-oncogenes and genes of the extracellular matrix proteins during butyrate induced glioma differentiation.

21 January 2018

1 reference

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Platelet-derived growth factor A-chain gene transcription is mediated by positive and negative regulatory regions in the promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00996300

Functional identification of regulatory elements within the promoter region of platelet-derived growth factor 2.

21 January 2018

1 reference

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Mechanism of regulation of PDGF-A chain gene expression by serum and TPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00996300

The 5' untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00996300

Alternative splicing of the platelet-derived growth factor A-chain transcript occurs in normal as well as tumor cells and is conserved among mammalian species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00996300

Alternatively spliced platelet-derived growth factor A-chain transcripts are not tumor specific but encode normal cellular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00996300

The alternatively spliced exon of the platelet-derived growth factor A chain encodes a nuclear targeting signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00996300

Expression of c-sis and other cellular proto-oncogenes in human sarcoma cell lines and biopsies

21 January 2018

1 reference

12 December 2020

Expression of platelet-derived growth factor (PDGF) and PDGF alpha- and beta-receptors in the peripheral nervous system: an analysis of sciatic nerve and dorsal root ganglia

1 reference

12 December 2020

Identification of individual amino acids in platelet‐derived growth factor that contribute to the specificity towards the β‐type receptor

1 reference

12 December 2020

Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells

1 reference

12 December 2020

Regulation of platelet-derived growth factor A messenger RNA translation in differentiating F9 teratocarcinoma cells.

1 reference

12 December 2020

IL-1 beta-induced expression of PDGF-AA isoform in rabbit articular chondrocytes is modulated by TGF-beta 1

1 reference

12 December 2020

Both homodimeric isoforms of PDGF (AA and BB) have mitogenic and chemotactic activity and stimulate phosphoinositol turnover

1 reference

12 December 2020

PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage.

1 reference

12 December 2020

Enhanced expression of the sis and c-myc oncogenes in human meningiomas

1 reference

12 December 2020

An S1 nuclease sensitive region in the PDGFA-chain gene promoter contains a positive transcriptional regulatory element

1 reference

12 December 2020

Platelet-derived growth factor and growth-related genes in rat lung. II. Effect of exposure to 85% O2

1 reference

12 December 2020

Characterization of a tyrosine-specific kinase activity in human fibroblast membranes stimulated by platelet-derived growth factor

1 reference

12 December 2020

Growth factor production by human thyroid carcinoma cells: abundant expression of a platelet-derived growth factor-B-like protein by a human papillary carcinoma cell line

1 reference

12 December 2020

Differences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functions

1 reference

12 December 2020

Cyclic AMP blocks expression of the c-sis gene in tumor cells

1 reference

12 December 2020

Arterial smooth muscle cells in primary culture produce a platelet-derived growth factor-like protein

1 reference

12 December 2020

Retinal pigment epithelial cells produce PDGF-like proteins and secrete them into their media

1 reference

12 December 2020

Differential regulation of platelet-derived growth factor genes in fetal rat lung fibroblasts.

1 reference

12 December 2020

Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation

1 reference

12 December 2020

Agents that increase cAMP accumulation block endothelial c-sis induction by thrombin and transforming growth factor-beta

1 reference

12 December 2020

Fish oils inhibit endothelial cell production of platelet-derived growth factor-like protein

1 reference

12 December 2020

Developmental distribution of platelet-derived growth factor in the mouse central nervous system

1 reference

12 December 2020

Spontaneous production of PDGF A-chain homodimer by rat lung fibroblasts in vitro

1 reference

12 December 2020

Distinct pathways mediate transcriptional regulation of platelet-derived growth factor B/c-sis expression

1 reference

12 December 2020

Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes

1 reference

12 December 2020

Expression of platelet-derived growth factor receptors in the developing chicken lens

1 reference

12 December 2020

Detection of c- sis Transcripts and Synthesis of PDGF-Like Proteins by Human Osteosarcoma Cells

1 reference

12 December 2020

Regulated expression of PDGF A-chain mRNA in human saphenous vein smooth muscle cells

1 reference

12 December 2020

Expression of platelet-derived growth factor B-chain in the mature rat brain and pituitary gland

1 reference

12 December 2020

Attachment of smooth muscle cells to collagen and their migration toward platelet-derived growth factor

1 reference

12 December 2020

Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-beta

1 reference

12 December 2020

Sequences of the 5' portion of the human c-sis gene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences

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12 December 2020

Vasoconstriction: a new activity for platelet-derived growth factor

1 reference

12 December 2020

Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor

1 reference

12 December 2020

Modulation of the sis gene transcript during endothelial cell differentiation in vitro

1 reference

12 December 2020

Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo.

1 reference

12 December 2020

Platelet-derived growth factor in chemotactic for fibroblasts

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12 December 2020

Platelet derived growth factor-A chain gene expression in cultured mesangial cells: regulation by phorbol ester at the level of mRNA abundance, transcription and mRNA stability

1 reference

12 December 2020

Production of PDGF-like growth factors by embryonal carcinoma cells and binding of PDGF to their endoderm-like differentiated cells

1 reference

12 December 2020

Interferon-gamma suppresses PDGF production from THP-1 cells and blood monocyte-derived macrophages

1 reference

12 December 2020

Rat brain capillary endothelial cells express functional PDGF B-type receptors

1 reference

12 December 2020

Expression of the c-sis gene and secretion of a platelet-derived growth factor-like protein by simian virus 40-transformed BHK cells

1 reference

12 December 2020

Human microvascular endothelial cells express receptors for platelet-derived growth factor

1 reference

12 December 2020

PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model

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12 December 2020

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system.

1 reference

12 December 2020

Expression of cellular oncogenes in human prostatic carcinoma cell lines

1 reference

12 December 2020

Interferon-gamma modulates messenger RNA levels of c-sis (PDGF-B chain), PDGF-A chain, and IL-1 beta genes in human vascular endothelial cells

1 reference

12 December 2020

Localization and functional analysis of DNase-I-hypersensitive sites in the human c-sis/PDGF-B gene transcription unit and its flanking regions

1 reference

12 December 2020

Endotoxin stimulates platelet-derived growth factor production from cultured human pulmonary endothelial cells.

1 reference

12 December 2020

Signal transduction by the receptors for platelet-derived growth factor

1 reference

12 December 2020

Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines

1 reference

12 December 2020

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors

1 reference

12 December 2020

Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells

1 reference

12 December 2020

Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth.

1 reference

12 December 2020

Expression of c-sis and c-fos genes in human meningiomas and neurinomas

1 reference

12 December 2020

Negative trans-acting mechanisms controlling expression of platelet-derived growth factor A and B MRNA in somatic cell hybrids

1 reference

12 December 2020

Demonstration of PDGF B-chain mRNA in glomeruli in mesangial proliferative nephritis by in situ hybridization

1 reference

12 December 2020

Human meningiomas co-express platelet-derived growth factor (PDGF) and PDGF-receptor genes and their protein products

1 reference

12 December 2020

Structural basis for the extracellular retention of PDGF A-chain using a synthetic peptide corresponding to exon 6

1 reference

12 December 2020

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1 reference

12 December 2020

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells

1 reference

12 December 2020

Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors

1 reference

12 December 2020

Aberrant expression of platelet-derived growth factor A-chain cDNAs due to cryptic splicing of RNA transcripts in COS-1 cells.

1 reference

12 December 2020

5' untranslated sequences determine degradative pathway for alternate PDGF B/c-sis mRNA's

1 reference

12 December 2020

Purification of human platelet-derived growth factor

1 reference

12 December 2020

Thrombin stimulates c-sis gene expression in microvascular endothelial cells

1 reference

12 December 2020

Enhancement of c-sis protooncogene transcription in bronchoalveolar mononuclear cells from patients with autoimmune diseases with lung involvement

1 reference

12 December 2020

Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance

1 reference

12 December 2020

Blood pressure regulates platelet-derived growth factor A-chain gene expression in vascular smooth muscle cells in vivo. An autocrine mechanism promoting hypertensive vascular hypertrophy

1 reference

12 December 2020

Phosphatidic acid modulates DNA synthesis, phospholipase C, and platelet-derived growth factor mRNAs in cultured mesangial cells. Role of protein kinase C.

1 reference

12 December 2020

Five PDGF B amino acid substitutions convert PDGF A to a PDGF B-like transforming molecule

1 reference

12 December 2020

A human glioma cell line secretes three structurally and functionally different dimeric forms of platelet-derived growth factor.

1 reference

12 December 2020

Thrombin stimulates PDGF production and monocyte adhesion through distinct intracellular pathways in human endothelial cells

1 reference

12 December 2020

Molecular localization of the transforming and secretory properties of PDGF A and PDGF B.

1 reference

12 December 2020

Developmental patterns of PDGF B-chain, PDGF-receptor, and alpha-actin expression in human glomerulogenesis.

1 reference

12 December 2020

Human platelet-derived growth factor (PDGF): amino-terminal amino acid sequence

1 reference

12 December 2020

The influence of oxidatively modified low density lipoproteins on expression of platelet-derived growth factor by human monocyte-derived macrophages

1 reference

12 December 2020

Developmental expression of PDGF, TGF-alpha, and TGF-beta genes in preimplantation mouse embryos

1 reference

12 December 2020

Identification and characterization of an essential, activating regulatory element of the human SIS/PDGFB promoter in human megakaryocytes

1 reference

12 December 2020

Binding of single-stranded oligonucleotides to a non-B-form DNA structure results in loss of promoter activity of the platelet-derived growth factor A-chain gene

1 reference

12 December 2020

Human iliac artery endothelial cells express both genes encoding the chains of platelet-derived growth factor (PDGF) and synthesize PDGF-like mitogen

1 reference

12 December 2020

Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells

1 reference

12 December 2020

Comparison of biological properties and transforming potential of human PDGF-A and PDGF-B chains

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12 December 2020

Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity

1 reference

12 December 2020

Increased expression of growth factor mRNAs accompanies viral transformation of rodent cells

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12 December 2020

Platelet alpha granules contain a growth factor for fibroblasts

1 reference

12 December 2020

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1 reference

12 December 2020

In vivo footprinting and functional analysis of the human c-sis/PDGF B gene promoter provides evidence for two binding sites for transcriptional activators

1 reference

12 December 2020

Highly purified fibroblast-derived growth factor, an SV40-transformed fibroblast-secreted mitogen, is closely related to platelet-derived growth factor

1 reference

12 December 2020

Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosis

1 reference

12 December 2020

cDNA clones reveal differences between human glial and endothelial cell platelet-derived growth factor A-chains

1 reference

12 December 2020

Production of Platelet-Derived Growth Factor–like Mitogen by Smooth-Muscle Cells from Human Atheroma

1 reference

12 December 2020

Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB

1 reference

12 December 2020

Platelet-derived growth factor (PDGF) A-chain mRNA heterogeneity generated by the use of alternative promoters and alternative polyadenylation sites

1 reference

12 December 2020

Successive activation of the platelet-derived growth factor beta receptor and platelet-derived growth factor B genes correlates with the genesis of human choriocarcinoma

1 reference

12 December 2020

Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells

1 reference

12 December 2020

Purification and properties of porcine platelet-derived growth factor

1 reference

12 December 2020

Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells

1 reference

12 December 2020

A tyrosinated peptide representing the alternatively spliced exon of the platelet-derived growth factor A-chain binds specifically to cultured cells and interferes with binding of several growth factors

1 reference

12 December 2020

Differential expression of platelet-derived growth factor and transforming growth factor genes in small- and non-small-cell human lung carcinoma lines

1 reference

12 December 2020

PDGF signalling is required for gastrulation of Xenopus laevis.

1 reference

12 December 2020

Alpha 1-adrenergic stimulation of platelet-derived growth factor A-chain gene expression in rat aorta

1 reference

12 December 2020

Determination and expression of platelet-derived growth factor-AA in bone cell cultures

1 reference

12 December 2020

Generation of fibrosarcomas in vivo by a retrovirus that expresses the normal B chain of platelet-derived growth factor and mimics the alternative splice pattern of the v-sis oncogene

1 reference

12 December 2020

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1 reference

12 December 2020

Arterial smooth muscle cells express platelet-derived growth factor (PDGF) A chain mRNA, secrete a PDGF-like mitogen, and bind exogenous PDGF in a phenotype- and growth state-dependent manner

1 reference

12 December 2020

SIS/PDGF-B expression in benign and malignant human breast lesions

1 reference

12 December 2020

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization

1 reference

12 December 2020

Novel human PDGFA gene transcripts derived by alternative mRNA splicing

1 reference

12 December 2020

Regulation of expression of the c-sis proto-oncogene

1 reference

12 December 2020

Differentially regulated production of platelet-derived growth factor and of transforming growth factor beta by a human teratocarcinoma cell line.

1 reference

12 December 2020

Platelet-derived growth factor is an autocrine growth stimulator in retinal pigmented epithelial cells

1 reference

12 December 2020

Expression of the human PDGF-B gene is regulated by both positively and negatively acting cell type-specific regulatory elements located in the first intron

1 reference

12 December 2020

Cell death and control of cell survival in the oligodendrocyte lineage

1 reference

12 December 2020

Developmentally regulated production of platelet-derived growth factor-like molecules

1 reference

12 December 2020

Regulated production of a pleiotropic cytokine-platelet-derived growth factor--by differentiating erythroid cells in vitro and in vivo

1 reference

12 December 2020

Gene regulation by the 5'-untranslated region of the platelet-derived growth factor A-chain

1 reference

12 December 2020

Expression of mouse PDGF-A and PDGF α-receptor genes during pre- and post-implantation development: Evidence for a developmental shift from an autocrine to a paracrine mode of action

1 reference

12 December 2020

Human keratinocytes are a major source of cutaneous platelet-derived growth factor

1 reference

12 December 2020

Mitogenic signals for thrombin in mesangial cells: regulation of phospholipase C and PDGF genes.

1 reference

12 December 2020

Coexpression of the genes for platelet-derived growth factor and its receptor in human T-cell lines infected with HTLV-I.

1 reference

12 December 2020

Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer

1 reference

12 December 2020

Chrysotile asbestos stimulates platelet-derived growth factor-AA production by rat lung fibroblasts in vitro: evidence for an autocrine loop

1 reference

12 December 2020

Platelet-derived growth factor gene expression in human atherosclerotic plaques and normal artery wall

1 reference

12 December 2020

Compartmentalization of PDGF on extracellular binding sites dependent on exon-6-encoded sequences

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12 December 2020

Comparison of production of transforming growth factor-beta and platelet-derived growth factor by normal human mesothelial cells and mesothelioma cell lines

1 reference

12 December 2020

Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop.

1 reference

12 December 2020

Promoter region of the human platelet-derived growth factor A-chain gene

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12 December 2020

Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

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12 December 2020

Induction of platelet-derived growth factor chain A gene expression in human smooth muscle cells by oxidized low density lipoproteins

1 reference

12 December 2020

Lipoprotein-mediated inhibition of endothelial cell production of platelet-derived growth factor-like protein depends on free radical lipid peroxidation

1 reference

12 December 2020

Structure and sequence of the human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) transcriptional unit

1 reference

12 December 2020

A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains

1 reference

12 December 2020

Expression and stability of c-sis mRNA in human glioblastoma cells

1 reference

12 December 2020

Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.

1 reference

12 December 2020

PDGF and its receptors following facial nerve axotomy in rats: expression in neurons and surrounding glia

1 reference

12 December 2020

Chemical and biological properties of a growth factor from human-cultured osteosarcoma cells: resemblance with platelet-derived growth factor

1 reference

12 December 2020

TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

1 reference

12 December 2020

SIS/PDGF-B promoter isolation and characterization of regulatory elements necessary for basal expression of the SIS/PDGF-B gene in U2-OS osteosarcoma cells.

1 reference

12 December 2020

Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression

1 reference

12 December 2020

Modulation of platelet-derived growth factor A- and B-chain/c-sis mRNA by tumor necrosis factor and other agents in adenocarcinoma cells

1 reference

12 December 2020

Platelet derived growth factor (PDGF) stimulates development of bovine embryos during the fourth cell cycle

1 reference

12 December 2020

Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines

1 reference

12 December 2020

Identification of the glucocorticoid suppressible mitogen from rat hepatoma cells as an angiogenic platelet-derived growth factor A-chain homodimer

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12 December 2020

Platelet-derived growth factor ligand and receptor expression by large vessel endothelium in vivo.

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12 December 2020

Human malignant mesothelioma cell lines express PDGF beta-receptors whereas cultured normal mesothelial cells express predominantly PDGF alpha-receptors

1 reference

12 December 2020

Production of platelet-derived growth factorlike protein by rat mesangial cells in culture

1 reference

12 December 2020

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells

1 reference

12 December 2020

Mesangial cells express PDGF mRNAs and proliferate in response to PDGF

1 reference

12 December 2020

Identification of processing events in the synthesis of platelet-derived growth factor-like proteins by human osteosarcoma cells

1 reference

12 December 2020

Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells

1 reference

12 December 2020

Platelets as a source of fibroblast growth-promoting activity.

1 reference

12 December 2020

An S1 nuclease-sensitive region in the first intron of human platelet-derived growth factor A-chain gene contains a negatively acting cell type-specific regulatory element

1 reference

12 December 2020

A novel human c-sis mRNA species is transcribed from a promoter in c-sis intron 1 and contains the code for an alternative PDGF B-like protein

1 reference

12 December 2020

Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.

1 reference

12 December 2020

Upregulation of platelet-derived growth factor-A and -B gene expression in alveolar macrophages of individuals with idiopathic pulmonary fibrosis

1 reference

12 December 2020

Human-Proto-Oncogene Nucleotide Sequences Corresponding to the Transforming Region of Simian Sarcoma Virus

1 reference

12 December 2020

The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains

1 reference

12 December 2020

The translational repression mediated by the platelet-derived growth factor 2/c-sis mRNA leader is relieved during megakaryocytic differentiation

1 reference

12 December 2020

Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing

1 reference

12 December 2020

Actions of platelet-derived growth factor isoforms in mesangial cells

1 reference

12 December 2020

Accumulation of PDGF B and cell-binding forms of PDGF A in the extracellular matrix

1 reference

12 December 2020

Two classes of PDGF receptor recognize different isoforms of PDGF

1 reference

12 December 2020

Platelet-derived growth factor gene expression in cultured human retinal pigment epithelial cells

1 reference

12 December 2020

Immunological study of in vitro maturation of human megakaryocytes

1 reference

12 December 2020

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture.

1 reference

12 December 2020

TGF-beta stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF-related peptides

1 reference

12 December 2020

Effects of PDGF on inositol phosphates, Ca2+, and contraction of mesangial cells

1 reference

12 December 2020

Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF

1 reference

12 December 2020

A novel mechanism regulating growth factor association with the cell surface: identification of a PDGF retention domain

1 reference

12 December 2020

Human platelet-derived growth factor. Purification and resolution into two active protein fractions

1 reference

12 December 2020

Human osteoblasts synthesize and respond to platelet-derived growth factor

1 reference

12 December 2020

Identification and characterization of polypeptide growth factors secreted by murine embryonal carcinoma cells.

1 reference

12 December 2020

Expression of c-sis/platelet-derived growth factor B, insulin-like growth factor I, and transforming growth factor alpha messenger RNAs and their respective receptor messenger RNAs in primary human gastric carcinomas: in vivo studies with in situ hy

1 reference

12 December 2020

Medulloblastoma cell line secretes platelet-derived growth factor

1 reference

12 December 2020

Interleukin 6 modulates c-sis gene expression in cultured human endothelial cells

1 reference

12 December 2020

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1 reference

12 December 2020

Thrombin-induced proliferation and expression of platelet-derived growth factor-A chain gene in human vascular smooth muscle cells

1 reference

12 December 2020

Differential expression of PDGF A- and B-chain genes and production of AA and AB dimers by activated human blood monocytes

1 reference

12 December 2020

Human prostate adenocarcinomas express in-vivo messenger-rnas and protein products for platelet-derived growth factor-B and its receptor

1 reference

12 December 2020

Identification of a cell retention signal in the B-chain of platelet-derived growth factor and in the long splice version of the A-chain

1 reference

12 December 2020

Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines

1 reference

12 December 2020

Platelet‐derived growth factor AA homodimer is the predominant isoform in human platelets and acute human wound fluid

1 reference

12 December 2020

Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture

1 reference

12 December 2020

PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve.

1 reference

12 December 2020

Shear-induced platelet-derived growth factor gene expression in human endothelial cells is mediated by protein kinase C

1 reference

12 December 2020

Production of PDGF-like growth factor by breast cancer cell lines

1 reference

12 December 2020

Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons.

1 reference

12 December 2020

Functional analysis of the human platelet-derived growth factor A-chain promoter region

1 reference

12 December 2020

Developmental expression of platelet-derived growth factor and its receptor in the human placenta

1 reference

12 December 2020

Expression of the platelet-derived growth factor 1 and 2 genes in human myeloid cell lines and monocytes

1 reference

12 December 2020

Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor

1 reference

12 December 2020

The biology of platelet-derived growth factor

1 reference

12 December 2020

Triggering signaling cascades by receptor tyrosine kinases

1 reference

12 December 2020

Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines

1 reference

12 December 2020

Platelet-derived growth factor and alternative splicing: a review

1 reference

12 December 2020

Cultured endothelial cells produce a platelet-derived growth factor-like protein

1 reference

12 December 2020

A glioma-derived analog to platelet-derived growth factor: demonstration of receptor competing activity and immunological crossreactivity

1 reference

12 December 2020

Induction of c-sis gene expression and synthesis of platelet-derived growth factor in human myeloid leukemia cells during monocytic differentiation

1 reference

12 December 2020

The Response of Cultured Human Normal Glial Cells to Growth Factors

1 reference

12 December 2020

Regulation of mesangial cell growth by polypeptide mitogens. Inhibitory role of transforming growth factor beta

1 reference

12 December 2020

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.

1 reference

12 December 2020

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF.

1 reference

12 December 2020

Alpha-thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells

1 reference

12 December 2020

Heparin-binding growth factor-1 stimulation of human endothelial cells induces platelet-derived growth factor A-chain gene expression

1 reference

12 December 2020

Tumor necrosis factor-induced expression of platelet-derived growth factor A-chain messenger RNA in fibroblasts

1 reference

12 December 2020

Reversible binding of platelet-derived growth factor-AA, -AB, and -BB isoforms to a similar site on the "slow" and "fast" conformations of alpha 2-macroglobulin

1 reference

12 December 2020

The effects of platelet-derived growth factor in cultured microvessel endothelial cells

1 reference

12 December 2020

Growth factor production by human colon carcinoma cell lines

1 reference

12 December 2020

Endothelin stimulates PDGF secretion in cultured human mesangial cells

1 reference

12 December 2020

Visceral glomerular epithelial cells can proliferate in vivo and synthesize platelet-derived growth factor B-chain.

1 reference

12 December 2020

Cloning a novel form of rat PDGF A-chain with a unique 5'-UT: regulation during development and in glomerulonephritis

1 reference

12 December 2020

Signal transduction by the platelet-derived growth factor receptor

1 reference

12 December 2020

Expression of c-sis (PDGF B-chain) and PDGF A-chain genes in ten human malignant mesothelioma cell lines derived from primary and metastatic tumors

1 reference

12 December 2020

Specific covalent binding of platelet-derived growth factor to human plasma alpha 2-macroglobulin

1 reference

12 December 2020

Platelet-derived growth factor: purification and partial characterization

1 reference

12 December 2020

Synthetic peptides representing the alternatively spliced exon of the platelet-derived growth factor A-chain modulate mitogenesis stimulated by normal human serum and several growth factors

1 reference

12 December 2020

A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain.

1 reference

12 December 2020

Cultured Kaposi's sarcoma-derived cells express functional PDGF A-type and B-type receptors

1 reference

12 December 2020

Expression of the insulin-like and platelet-derived growth factor genes in human uterine tissues

1 reference

12 December 2020

Increased expression of PDGF A- and B-chain genes in rat lungs with hypoxic pulmonary hypertension

1 reference

12 December 2020

PDGF ligand and receptor gene expression during repair of arterial injury

1 reference

12 December 2020

Transcriptional control of the platelet-derived growth factor subunit genes

1 reference

12 December 2020

Selective expression of PDGF A and its receptor during early mouse embryogenesis.

1 reference

12 December 2020

Growth factor messenger RNA expression by human breast fibroblasts from benign and malignant lesions

1 reference

12 December 2020

Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA.

1 reference

12 December 2020

Localization of PDGF-B protein in macrophages in all phases of atherogenesis

1 reference

12 December 2020

1 reference

12 December 2020

Multiple elements in the 5' untranslated region down-regulate c-sis messenger RNA translation.

1 reference

12 December 2020

Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class

1 reference

12 December 2020

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1 reference

12 December 2020

Structure and function of platelet-derived growth factor (PDGF) and related proteins

1 reference

12 December 2020

Platelet-derived growth factor ligand and receptor subunit mRNA in the Sertoli and Leydig cells of the rat testis

1 reference

12 December 2020

Expression of platelet-derived growth factor and its receptors in neuroendocrine tumors of the digestive system

1 reference

12 December 2020

Production of platelet-derived growth factor by cultured Wilms' tumor cells and fetal kidney cells

1 reference

12 December 2020

Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury

1 reference

12 December 2020

Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor

1 reference

12 December 2020

1 reference

12 December 2020

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1 reference

12 December 2020

Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation

1 reference

12 December 2020

Structure and nucleotide sequence of the 5' region of the human and feline c-sis proto-oncogenes

1 reference

12 December 2020

Injury induces in vivo expression of platelet-derived growth factor (PDGF) and PDGF receptor mRNAs in skin epithelial cells and PDGF mRNA in connective tissue fibroblasts

1 reference

12 December 2020

Effects of interferon-gamma on proto-oncogene expression during induction of human monocytic differentiation.

1 reference

12 December 2020

Modified low density lipoproteins suppress production of a platelet-derived growth factor-like protein by cultured endothelial cells

1 reference

12 December 2020

Expression of platelet-derived growth factor and its receptor in AIDS-related Kaposi sarcoma in vivo suggests paracrine and autocrine mechanisms of tumor maintenance

1 reference

12 December 2020

Plasma binding proteins for platelet-derived growth factor that inhibit its binding to cell-surface receptors

1 reference

12 December 2020

New roles for PDGF and CNTF in controlling the timing of glial cell differentiation in the optic nerve

1 reference

12 December 2020

Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens

1 reference

12 December 2020

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat

1 reference

12 December 2020

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines

1 reference

12 December 2020

Novel cis-acting elements in the human platelet-derived growth factor B-chain core promoter that mediate gene expression in cultured vascular endothelial cells

1 reference

12 December 2020

The expression of the platelet-derived and transforming growth factor genes in human nonsmall lung cancer cell lines is related to tumor stroma formation in nude mice tumors

1 reference

12 December 2020

Expression of multiple growth factors in a human lung cancer cell line

1 reference

12 December 2020

Cultured human endothelial cells express platelet-derived growth factor A chain.

1 reference

12 December 2020

Platelet-derived growth factor production by human umbilical vein endothelial cells is regulated by basic fibroblast growth factor

1 reference

12 December 2020

Effect of the different dimeric forms of the platelet-derived growth factor on cellular responses in mouse Swiss 3T3 fibroblasts

1 reference

12 December 2020

Structure of the murine c-sis proto-oncogene (Sis, PDGFB) encoding the B chain of platelet-derived growth factor.

1 reference

12 December 2020

Fluid shear stress differentially modulates expression of genes encoding basic fibroblast growth factor and platelet-derived growth factor B chain in vascular endothelium

1 reference

12 December 2020

Expression of cellular oncogenes during embryonic and fetal development of the mouse

1 reference

12 December 2020

Platelets, platelet-derived growth factor and arteriosclerosis

1 reference

12 December 2020

Synthesis of PDGF by cultured human T cells transformed with HTLV-I and II.

1 reference

12 December 2020

Synthesis and assembly of a functionally active recombinant platelet-derived growth factor AB heterodimer

1 reference

12 December 2020

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

1 reference

12 December 2020

Platelet-derived growth factor. Phorbol ester induces the expression of the B-chain but not of the A-chain in HEL cells

1 reference

12 December 2020

Dimerization of B-type platelet-derived growth factor receptors occurs after ligand binding and is closely associated with receptor kinase activation

1 reference

12 December 2020

Localization of PDGF A and PDGFR alpha mRNA in Xenopus embryos suggests signalling from neural ectoderm and pharyngeal endoderm to neural crest cells

1 reference

12 December 2020

Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation

1 reference

12 December 2020

Expression of platelet-derived growth factor and its receptor in rat neuronal and astroglial cultures.

1 reference

12 December 2020

Platelet-derived growth factor in idiopathic pulmonary fibrosis

1 reference

12 December 2020

Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes

1 reference

12 December 2020

Transcriptional regulation of the A and B chain genes of platelet-derived growth factor in microvascular endothelial cells.

1 reference

12 December 2020

Transformation of NIH 3T3 cells by a human c-sis cDNA clone

1 reference

12 December 2020

Genetic organization of the c-sis transcription unit

1 reference

12 December 2020

Expression of platelet‐derived growth factor (PDGF) and PDGF receptor genes in the developing rat brain

1 reference

12 December 2020

Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor.

1 reference

12 December 2020

Human platelet-derived growth factor (PDGF): purification of PDGF-I and PDGF-II and separation of their reduced subunits

1 reference

12 December 2020

Detection of PDGF-2 homodimers in human tumor cells

1 reference

12 December 2020

Human peripheral blood monocytes secrete a unique form of PDGF

1 reference

12 December 2020

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor

1 reference

12 December 2020

Enhancement of c-sis proto-oncogene transcription in bronchoalveolar mononuclear cells from patients with pulmonary sarcoidosis

1 reference

12 December 2020

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

1 reference

12 December 2020

Stable expression of human platelet-derived growth factor B chain by bovine aortic endothelial cells. Matrix association and selective proteolytic cleavage by thrombin

1 reference

12 December 2020

Structural and functional studies on platelet-derived growth factor

1 reference

12 December 2020

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types

1 reference

12 December 2020

Malignant transformation of NIH 3T3 fibroblasts by human c-sis is dependent upon the level of oncogene expression

1 reference

12 December 2020

The expression of PDGF alpha- and beta-receptors in subpopulations of PDGF-producing cells implicates autocrine stimulatory loops in the control of proliferation in cytotrophoblasts that have invaded the maternal endometrium

1 reference

12 December 2020

Growth factors and wound healing: platelet-derived growth factor as a model cytokine

1 reference

12 December 2020

PDGF A-chain gene is expressed by mammalian neurons during development and in maturity

1 reference

12 December 2020

Selective expression of mRNA encoding platelet-derived growth factor B chain following transfection of foreign genes into cell lines derived from baby hamster kidney

1 reference

12 December 2020

Platelet-derived growth factor in autocrine transformation

1 reference

12 December 2020

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents

1 reference

12 December 2020

H2O2 increases expression of pulmonary artery endothelial cell platelet-derived growth factor mRNA

1 reference

12 December 2020

Expression of the sis gene by endothelial cells in culture and in vivo

1 reference

12 December 2020

Expression of PDGF A-chain and beta-receptor genes during rat myoblast differentiation

1 reference

12 December 2020

Identification of three types of PDGF-A chain gene transcripts in rabbit vascular smooth muscle and their regulated expression during development and by angiotensin II

1 reference

12 December 2020

Expression of growth factor ligand and receptor genes in the preimplantation bovine embryo

1 reference

12 December 2020

DNase-I-hypersensitive sites located far upstream of the human c-sis/PDGF-B gene comap with transcriptional enhancers and a silencer and are preceded by (part of) a new transcription unit

1 reference

12 December 2020

Possible positive autocrine feedback in the prereplicative phase of human fibroblasts

1 reference

12 December 2020

A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro

1 reference

12 December 2020

Identification of mRNA for PDGF B-chain in human megakaryocytes isolated using a novel immunomagnetic separation method

1 reference

12 December 2020

Alternative RNA splicing affects function of encoded platelet-derived growth factor A chain

1 reference

12 December 2020

Growth factor expression during rat development: a comparison of TGF-beta 3, TGF-alpha, bFGF, PDGF and PDGF-R

1 reference

12 December 2020

Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells

1 reference

12 December 2020

Cultured primate aortic smooth muscle cells express both the PDGF-A and PDGF-B genes but do not secrete mitogenic activity or dimeric platelet-derived growth factor protein

1 reference

12 December 2020

3-Deazaadenosine inhibits thrombin-stimulated platelet-derived growth factor production and endothelial-leukocyte adhesion molecule-1-mediated monocytic cell adhesion in human aortic endothelial cells

1 reference

12 December 2020

Platelet-derived growth factor ligands and receptors immunolocalized in proliferative retinal diseases

1 reference

12 December 2020

Expression of growth factor and epidermal growth factor receptor encoded transcripts in human gastric tissues

1 reference

12 December 2020

Mechanical strain induces growth of vascular smooth muscle cells via autocrine action of PDGF.

1 reference

12 December 2020

Shear stress increases endothelial platelet-derived growth factor mRNA levels

1 reference

12 December 2020

A nuclear protein in mesangial cells that binds to the promoter region of the platelet-derived growth factor-A chain gene. Induction by phorbol ester

1 reference

12 December 2020

Transforming growth factor-beta induces platelet-derived growth factor (PDGF) messenger RNA and PDGF secretion while inhibiting growth in normal human mammary epithelial cells

1 reference

12 December 2020

Control of the expression of c-sis mRNA in human glioblastoma cells by phorbol ester and transforming growth factor beta 1.

1 reference

12 December 2020

A common PDGF receptor is activated by homodimeric A and B forms of PDGF

1 reference

12 December 2020

Autoinduction of platelet derived growth factor (PDGF) A-chain mRNA expression in a human malignant melanoma cell line and growth inhibitory effects of PDGF-A-chain mRNA-specific antisense molecules

1 reference

12 December 2020

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

1 reference

12 December 2020

Neuroblastoma cells express c-sis and produce a transforming growth factor antigenically related to the platelet-derived growth factor.

1 reference

12 December 2020

Rat skeletal myoblasts and arterial smooth muscle cells express the gene for the A chain but not the gene for the B chain (c-sis) of platelet-derived growth factor (PDGF) and produce a PDGF-like protein

1 reference

12 December 2020

sis (platelet-derived growth factor B chain) gene transcript levels are elevated in human atherosclerotic lesions compared to normal artery

1 reference

12 December 2020

Induced differentiation of K562 leukemia cells: a model for studies of gene expression in early megakaryoblasts

1 reference

12 December 2020

Splicing of the platelet-derived-growth-factor A-chain mRNA in human malignant mesothelioma cell lines and regulation of its expression

1 reference

12 December 2020

Migratory and proliferative effect of platelet-derived growth factor in rabbit retinal endothelial cells: evidence of an autocrine pathway of platelet-derived growth factor

1 reference

12 December 2020

Platelet-Derived Growth Factor A Chain Is Maternally Encoded in Xenopus Embryos

1 reference

12 December 2020

Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets

1 reference

12 December 2020

Expression of messenger RNAs for platelet-derived growth factor and its receptors in human sarcoma cell lines

1 reference

12 December 2020

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity

1 reference

12 December 2020

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly

1 reference

12 December 2020

PKC alpha regulates thrombin-induced PDGF-B chain gene expression in mesangial cells

1 reference

12 December 2020

An S1 nuclease-sensitive homopurine/homopyrimidine domain in the PDGF A-chain promoter contains a novel binding site for the growth factor-inducible protein EGR-1

1 reference

12 December 2020

Tumor necrosis factor-mediated release of platelet-derived growth factor from cultured endothelial cells

1 reference

12 December 2020

Altered regulation of platelet-derived growth factor A-chain and c-fos gene expression in senescent progeria fibroblasts

1 reference

12 December 2020

A platelet-derived growth factor analog produced by a human clonal glioma cell line.

1 reference

12 December 2020

Modulation of transcription of the platelet-derived growth factor A-chain gene by a promoter region sensitive to S1 nuclease

1 reference

12 December 2020

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1

1 reference

12 December 2020

Constitutive production of platelet-derived growth factor-like proteins by human prostate carcinoma cell lines.

1 reference

12 December 2020

Role of platelet-derived growth factor in wound healing

1 reference

12 December 2020

Kidney epithelial cells express c-sis protooncogene and secrete PDGF-like protein

1 reference

12 December 2020

Aberrant oncogene expression in uncultured human sarcoma and melanoma

1 reference

12 December 2020

Chromosomal localization of the human homolog (c-sis) of the simian sarcoma virus onc gene

1 reference

12 December 2020

Malignant epithelial cells in primary human lung carcinomas coexpress in vivo platelet-derived growth factor (PDGF) and PDGF receptor mRNAs and their protein products

1 reference

12 December 2020

Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines

1 reference

12 December 2020

Autocrine control of human meningioma proliferation: secretion of platelet-derived growth-factor-like molecules

1 reference

12 December 2020

Evidence of autocrine regulation in human hepatoma cell lines

1 reference

12 December 2020

Uric acid stimulates vascular smooth muscle cell proliferation by increasing platelet-derived growth factor A-chain expression

1 reference

12 December 2020

Induction of platelet-derived growth factor B/c-sis by the v-erbA oncogene in glial cells.

1 reference

12 December 2020

Increased platelet-derived growth factor A-chain expression in human uterine smooth muscle cells during the physiologic hypertrophy of pregnancy

1 reference

12 December 2020

Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping

1 reference

12 December 2020

The half-lives of platelet-derived growth factor A- and B-chain mRNAS are similar in endothelial cells and unaffected by heparin-binding growth factor-1 or cycloheximide

1 reference

12 December 2020

Stimulation of DNA synthesis in cultured primary human mesothelial cells by specific growth factors

1 reference

12 December 2020

The Wilms' tumor gene product, WT1, represses transcription of the platelet-derived growth factor A-chain gene

1 reference

12 December 2020

Site-specific methylation inhibits transcriptional activity of platelet-derived growth factor A-chain promoter

1 reference

12 December 2020

PDGF and its receptors in the developing rodent retina and optic nerve

1 reference

12 December 2020

Ultrastructural localization of platelet-derived growth factor and related factors in normal and transformed cells

1 reference

12 December 2020

Identification of a single-stranded DNA-binding protein that interacts with an S1 nuclease-sensitive region in the platelet-derived growth factor A-chain gene promoter.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00996300

1 reference

27 September 2017

1 reference

PubMed ID

8858568