(Q41154435)

27 September 2017

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs (English)

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27 September 2017

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van Ham SM

1

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27 September 2017

Grüneberg U

2

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27 September 2017

Malcherek G

3

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27 September 2017

Bröker I

4

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27 September 2017

Melms A

5

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27 September 2017

Trowsdale J

6

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27 September 2017

language of work or name

English

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publication date

1 November 1996

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Journal of Experimental Medicine

27 September 2017

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27 September 2017

184

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27 September 2017

5

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27 September 2017

2019-2024

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H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Self-release of CLIP in peptide loading of HLA-DR molecules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Role for intracellular proteases in the processing and transport of class II HLA antigens

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

A new human HLA class II-related locus, DM

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Long-lived complexes between peptide and class II major histocompatibility complex are formed at low pH with no requirement for pH neutralization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Supermotifs enable natural invariant chain-derived peptides to interact with many major histocompatibility complex-class II molecules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Mediation by HLA-DM of dissociation of peptides from HLA-DR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Myelin basic protein peptide complexes with the class II MHC molecules I-Au and I-Ak form and dissociate rapidly at neutral pH.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Natural peptide ligand motifs of two HLA molecules associated with myasthenia gravis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Production of soluble MHC class II proteins with covalently bound single peptides

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Analysis of allele-specific contact sites of natural HLA-DR17 ligands

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

Two populations of Ia-like molecules on a human B cell line.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2192865

19 August 2018

Identifiers

DOI

10.1084/JEM.184.5.2019

1 reference

27 September 2017

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27 September 2017

1 reference