(Q41165164)

27 September 2017

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title

Cyclooxygenase 1 and 2 in rheumatic disease: implications for nonsteroidal anti-inflammatory drug therapy (English)

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27 September 2017

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Spangler RS

1

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27 September 2017

publication date

1 August 1996

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Seminars in Arthritis and Rheumatism

27 September 2017

published in

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27 September 2017

volume

26

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27 September 2017

issue

1

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27 September 2017

page(s)

435-446

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New insights into the mode of action of anti-inflammatory drugs.

27 September 2017

cites work

1 reference

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7 January 2021

Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide

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7 January 2021

Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages

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7 January 2021

Induction of cyclooxygenase-2 is responsible for interleukin-1 beta-dependent prostaglandin E2 synthesis by human lung fibroblasts

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7 January 2021

In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis.

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7 January 2021

Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

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7 January 2021

Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

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7 January 2021

Prostaglandin endoperoxide synthase: regulation of enzyme expression

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7 January 2021

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

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7 January 2021

Tumor promoter-inducible genes are differentially expressed in the developing mouse

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Localization of prostaglandin endoperoxide synthase in neurons and glia in monkey brain.

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7 January 2021

Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2.

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7 January 2021

Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system

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7 January 2021

Nonsteroidal antiinflammatory drugs--differences and similarities

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7 January 2021

Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs

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7 January 2021

Comparative toxicity of non-steroidal anti-inflammatory agents

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7 January 2021

Effect on gastric and duodenal mucosal prostaglandins of repeated intake of therapeutic doses of naproxen and etodolac in rheumatoid arthritis

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7 January 2021

Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs

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7 January 2021

The effect of nabumetone and its principal active metabolite on in vitro human gastric mucosal prostanoid synthesis and platelet function

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7 January 2021

Etodolac: effect on prostaglandin concentrations in gastric mucosa of rats

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7 January 2021

Nonsteroidal antiinflammatory drugs and the gastrointestinal tract. The double-edged sword

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7 January 2021

Adverse effects of nonsteroidal anti-inflammatory drugs on renal function

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7 January 2021

Comparative effects of nabumetone, sulindac, and indomethacin on urinary prostaglandin excretion and platelet function in volunteers

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7 January 2021

Effects of non-narcotic analgesics on the kidney.

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7 January 2021

Acute Oliguric Renal Failure Induced by Indomethacin: Possible Mechanism

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7 January 2021

Renal effects of ibuprofen, piroxicam, and sulindac in patients with asymptomatic renal failure. A prospective, randomized, crossover comparison

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7 January 2021

Metabolism of nabumetone (BRL 14777) by various species including man

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7 January 2021

Effects of sulindac and indomethacin on renal prostaglandin synthesis

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7 January 2021

Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction

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7 January 2021

Eicosanoids in experimental and human renal disease

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7 January 2021

Ethanol potentiation of aspirin-induced prolongation of the bleeding time

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7 January 2021

Effect of drug-induced platelet dysfunction on surgical bleeding

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7 January 2021

Low-dose preoperative aspirin therapy, postoperative blood loss, and transfusion requirements

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7 January 2021

Effect of nabumetone (BRL 14777), a new anti-inflammatory drug, on human platelet reactivity ex vivo: comparison with naproxen

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7 January 2021

Inhibition of neutrophil function by aspirin-like drugs (NSAIDS): requirement for assembly of heterotrimeric G proteins in bilayer phospholipid

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7 January 2021

Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs.

1 reference

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7 January 2021

Tenidap, in contrast to several available nonsteroidal antiinflammatory drugs, potently inhibits the release of activated neutrophil collagenase

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7 January 2021

Nonsteroidal anti-inflammatory drugs and peptic ulcer disease

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7 January 2021

Gastrointestinal complications of nonsteroidal anti-inflammatory drugs: prophylactic and therapeutic strategies

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7 January 2021

Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans.

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7 January 2021

Gastrointestinal damage demonstrated with nabumetone or etodolac in preclinical studies

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7 January 2021

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

1 reference

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7 January 2021

Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.

1 reference

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7 January 2021

10.1016/S0049-0172(96)80024-2

Identifiers

DOI

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27 September 2017

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