(Q41181055)

27 September 2017

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title

Activating mechanism of CNTF and related cytokines (English)

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27 September 2017

M Inoue

1

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27 September 2017

C Nakayama

series ordinal

2

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27 September 2017

H Noguchi

series ordinal

3

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27 September 2017

publication date

1 June 1996

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27 September 2017

published in

Molecular Neurobiology

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27 September 2017

volume

12

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27 September 2017

issue

3

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27 September 2017

page(s)

195-209

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https://scigraph.springernature.com/pub.10.1007/bf02755588

27 September 2017

exact match

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cites work

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https://api.crossref.org/works/10.1007%2FBF02755588

Human ciliary neurotrophic factor: a structure-function analysis

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02755588

Cleavage of a hydrophilic C-terminal domain increases growth-inhibitory activity of oncostatin M

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02755588

Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

STAT3 and STAT5B are targets of two different signal pathways activated by hematopoietin receptors and control transcription via separate cytokine response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

Distinct regions of the human granulocyte-colony-stimulating factor receptor cytoplasmic domain are required for proliferation and gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

Separate signaling mechanisms are involved in the control of STAT protein activation and gene regulation via the interleukin 6 response element by the box 3 motif of gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

A growth hormone agonist produced by targeted mutagenesis at binding site 1. Evidence that site 1 regulates bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02755588

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

12 December 2020

Disruption of the CNTF gene results in motor neuron degeneration.

1 reference

12 December 2020

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

1 reference

12 December 2020

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

1 reference

12 December 2020

A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury

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12 December 2020

Target-derived molecules that influence the development of neurons in the avian ciliary ganglion

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12 December 2020

Structure-function studies of human ciliary neurotrophic factor.

1 reference

12 December 2020

Recombinant human and rat ciliary neurotrophic factors

1 reference

12 December 2020

Alanine-scanning mutagenesis of human interleukin-11: identification of regions important for biological activity.

1 reference

12 December 2020

Functional domains of the granulocyte colony-stimulating factor receptor

1 reference

12 December 2020

CNTF variants with increased biological potency and receptor selectivity define a functional site of receptor interaction

1 reference

12 December 2020

Signal transduction through gp130 that is shared among the receptors for the interleukin 6 related cytokine subfamily

1 reference

12 December 2020

The substitution of cysteine 17 of recombinant human G-CSF with alanine greatly enhanced its stability

1 reference

12 December 2020

Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cells

1 reference

12 December 2020

Development of a human interleukin-6 receptor antagonist.

1 reference

12 December 2020

The binding pattern of a neutralizing monoclonal antibody to mutant oncostatin M molecules is correlated with functional activity

1 reference

12 December 2020

Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

1 reference

12 December 2020

Ciliary neurotrophic factor: a review

1 reference

12 December 2020

Crystal structure of canine and bovine granulocyte-colony stimulating factor (G-CSF)

1 reference

12 December 2020

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

1 reference

12 December 2020

Ciliary neurotrophic factor is an endogenous pyrogen

1 reference

12 December 2020

Inter-species chimeras of leukaemia inhibitory factor define a major human receptor-binding determinant

1 reference

12 December 2020

Alanine-scanning mutagenesis of human prolactin: importance of the 58-74 region for bioactivity

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12 December 2020

Cytokine receptor signalling

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12 December 2020

Rational design of a receptor super-antagonist of human interleukin-6.

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12 December 2020

Erythropoietin structure-function relationships: high degree of sequence homology among mammals.

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12 December 2020

The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor

1 reference

12 December 2020

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

12 December 2020

Ciliary neurotrophic factor and its receptor complex

1 reference

12 December 2020

Protein hormones and their receptors

1 reference

12 December 2020

Electrostatic stabilization in four-helix bundle proteins

1 reference

12 December 2020

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1 reference

12 December 2020

Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons

1 reference

12 December 2020

Site-directed mutagenesis of human CNTF: Functional analysis of recombinant variants

1 reference

12 December 2020

The addition of nine residues at the C-terminus of human prolactin drastically alters its biological properties

1 reference

12 December 2020

Recombinant IL-6 activates p42 and p44 mitogen-activated protein kinases in the IL-6 responsive B cell line, AF-10.

1 reference

12 December 2020

High and low affinity receptors for human interleukin for DA cells/leukemia inhibitory factor on human cells. Molecular characterization and cellular distribution.

1 reference

12 December 2020

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12 December 2020

Cytokine signal transduction

1 reference

12 December 2020

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

1 reference

12 December 2020

Analysis of function and expression of the chick GPA receptor (GPAR alpha) suggests multiple roles in neuronal development

1 reference

12 December 2020

Ciliary neurotrophic factor as an injury factor

1 reference

12 December 2020

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1 reference

12 December 2020

Two distinct signalling pathways are involved in the control of the biphasic junB transcription induced by interleukin-6 in the B cell hybridoma 7TD1.

1 reference

12 December 2020

Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy

1 reference

12 December 2020

Neuropoietic cytokines in the hematopoietic fold

1 reference

12 December 2020

Systemic administration of ciliary neurotrophic factor induces cachexia in rodents

1 reference

12 December 2020

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1 reference

12 December 2020

Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death.

1 reference

12 December 2020

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).

1 reference

12 December 2020

The alphas, betas, and kinases of cytokine receptor complexes

1 reference

12 December 2020

Disulfide bond assignment and identification of regions required for functional activity of oncostatin M

1 reference

12 December 2020

Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing

1 reference

12 December 2020

Mutagenesis of human granulocyte colony stimulating factor

1 reference

12 December 2020

Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.

1 reference

12 December 2020

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

12 December 2020

The regulation and function of p21ras in T cells

1 reference

12 December 2020

Cholinergic neuronotrophic factors: I. Survival, neurite outgrowth and choline acetyltransferase activity in monolayer cultures from chick embryo ciliary ganglia

1 reference

12 December 2020

Leukemia Inhibitory Factor and Ciliary Neurotrophic Factor Increase Activated Ras in a Neuroblastoma Cell Line and in Sympathetic Neuron Cultures

1 reference

12 December 2020

Recombinant human CNTF receptor alpha: production, binding stoichiometry, and characterization of its activity as a diffusible factor.

1 reference

12 December 2020

Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

12 December 2020

Ciliary neurotrophic factor: Pharmacokinetics and acute-phase response in rat

1 reference

12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

1 reference

12 December 2020

A null mutation in the human CNTF gene is not causally related to neurological diseases

1 reference

12 December 2020

Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines

1 reference

12 December 2020

Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation

1 reference

12 December 2020

STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines

1 reference

12 December 2020

Internal deletions of amino acids 29-42 of human interleukin-6 (IL-6) differentially affect bioactivity and folding.

1 reference

12 December 2020

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

12 December 2020

Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component

1 reference

12 December 2020

Neurotrophic factors: an evolutionary perspective

1 reference

12 December 2020

Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.

1 reference

12 December 2020

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6

1 reference

12 December 2020

A model for the interaction of the GM-CSF, IL-3 and IL-5 receptors with their ligands

1 reference

12 December 2020

Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokines

1 reference

12 December 2020

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

1 reference

12 December 2020

The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines

1 reference

12 December 2020

Cloning and expression of human ciliary neurotrophic factor

1 reference

12 December 2020

D1 cap region involved in the receptor recognition and neural cell survival activity of human ciliary neurotrophic factor

1 reference

12 December 2020

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

1 reference

12 December 2020

Essential function of LIF receptor in motor neurons

1 reference

12 December 2020

GPA and CNTF produce similar effects in sympathetic neurones but differ in receptor binding

1 reference

12 December 2020

Protein Motifs. 7. The four-helix bundle: what determines a fold?

1 reference

12 December 2020

Signaling by the cytoplasmic domain of hematopoietin receptors involves two distinguishable mechanisms in hepatic cells

1 reference

12 December 2020

The receptor for ciliary neurotrophic factor

1 reference

12 December 2020

Structural and functional characterisation of recombinant human erythropoietin analogues

1 reference

12 December 2020

Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling

1 reference

12 December 2020

Structure-function relationships in human interleukin-11. Identification of regions involved in activity by chemical modification and site-directed mutagenesis

1 reference

12 December 2020

Effect of semi-random mutagenesis at the C-terminal 4 amino acids of human interleukin-6 on its biological activity

1 reference

12 December 2020

The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding

1 reference

12 December 2020

The molecular design of human IL-6 receptor antagonists

1 reference

12 December 2020

SH2 domains recognize specific phosphopeptide sequences

1 reference

12 December 2020

Engineering human prolactin to bind to the human growth hormone receptor

1 reference

12 December 2020

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

12 December 2020

Generation of interleukin-6 receptor antagonists by molecular-modeling guided mutagenesis of residues important for gp130 activation

1 reference

12 December 2020

Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation

1 reference

12 December 2020

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

1 reference

12 December 2020

Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.

1 reference

12 December 2020

Involvement of Janus kinases, p52shc, Raf-1, and MEK-1 in the IL-6-induced mitogen-activated protein kinase cascade of a growth-responsive B cell line.

1 reference

12 December 2020

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

1 reference

12 December 2020

Characterisation of high-affinity and low-affinity receptors for ciliary neurotrophic factor

1 reference

12 December 2020

Neurotrophic factors enter the clinic.

1 reference

12 December 2020

Saturation mutagenesis of the human interleukin 6 receptor-binding site: implications for its three-dimensional structure

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02755588

1 reference

Dimensions Publication ID

27 September 2017

1048074905

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1 reference