(Q41188806)

28 September 2017

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title

Hepatocyte growth factor/scatter factor-Met signaling in tumorigenicity and invasion/metastasis (English)

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28 September 2017

M Jeffers

1

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PubMed ID

8892055

28 September 2017

S Rong

series ordinal

2

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PubMed ID

8892055

28 September 2017

G F Vande Woude

series ordinal

3

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28 September 2017

1 September 1996

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Journal of Molecular Medicine

28 September 2017

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28 September 2017

74

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28 September 2017

505-513

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28 September 2017

9

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A novel protease obtained from FBS-containing culture supernatant, that processes single chain form hepatocyte growth factor to two chain form in serum-free culture

28 September 2017

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12 December 2020

Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells

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12 December 2020

Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients.

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12 December 2020

Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions

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12 December 2020

Autocrine hepatocyte growth factor/scatter factor-Met signaling induces transformation and the invasive/metastastic phenotype in C127 cells

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12 December 2020

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

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12 December 2020

A protein tyrosine phosphatase activity associated with the hepatocyte growth factor/scatter factor receptor.

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12 December 2020

The urokinase receptor: involvement in cell surface proteolysis and cancer invasion

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12 December 2020

Met expression and sarcoma tumorigenicity.

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12 December 2020

Overexpression of c-met proto-oncogene but not epidermal growth factor receptor or c-erbB-2 in primary human colorectal carcinomas

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12 December 2020

Tumor necrosis factor stimulates epithelial tumor cell motility

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12 December 2020

Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness

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12 December 2020

Frequent amplification of the c-met gene in scirrhous type stomach cancer.

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12 December 2020

Matrix metalloproteinases: a review

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12 December 2020

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

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12 December 2020

Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer

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12 December 2020

Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger.

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12 December 2020

The presence of scatter factor in patients with metastatic spread to the pleura

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12 December 2020

Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell

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12 December 2020

Autocrine stimulation of motility in SBC-5 human lung carcinoma cells by a two-kringle variant of HGF

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12 December 2020

A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor

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12 December 2020

Cell-associated plasminogen activation: regulation and physiological functions

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12 December 2020

Scatter factor/hepatocyte growth factor is essential for liver development

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12 December 2020

Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

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12 December 2020

New Method for Detecting Cellular Transforming Genes

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12 December 2020

Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros

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12 December 2020

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

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12 December 2020

The tyrosine-phosphorylated hepatocyte growth factor/scatter factor receptor associates with phosphatidylinositol 3-kinase

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12 December 2020

Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development

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12 December 2020

Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells.

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12 December 2020

Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity

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12 December 2020

Activation of hepatocyte growth factor by two homologous proteases, blood-coagulation factor XIIa and hepatocyte growth factor activator

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12 December 2020

Amplification and overexpression of the met gene in spontaneously transformed NIH3T3 mouse fibroblasts

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12 December 2020

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells

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12 December 2020

Structure-function analysis of hepatocyte growth factor: identification of variants that lack mitogenic activity yet retain high affinity receptor binding

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12 December 2020

Mechanism of met oncogene activation

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12 December 2020

A quantitative in vitro focus assay for bovine papilloma virus

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12 December 2020

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

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12 December 2020

Scatter factor induces blood vessel formation in vivo

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12 December 2020

Scatter factor modulates the metastatic phenotype of the EMT6 mouse mammary tumor

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12 December 2020

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor

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12 December 2020

Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and inducti

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12 December 2020

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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12 December 2020

Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer

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12 December 2020

Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation

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12 December 2020

Transformation of human osteosarcoma cells by a chemical carcinogen

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12 December 2020

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

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12 December 2020

Tumor cell interactions with the extracellular matrix during invasion and metastasis

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12 December 2020

Involvement of hepatocyte growth factor in kidney development

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12 December 2020

Purification and subunit structure of hepatocyte growth factor from rat platelets

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12 December 2020

Expression of the Met/HGF receptor in normal and neoplastic human tissues

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12 December 2020

Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor

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12 December 2020

Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells

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12 December 2020

Stimulatory effects of hepatocyte growth factor on normal and neoplastic human bronchial epithelial cells

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12 December 2020

Tumorigenesis induced by coexpression of human hepatocyte growth factor and the human met protooncogene leads to high levels of expression of the ligand and receptor

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12 December 2020

Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells

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12 December 2020

Hepatocyte growth factor/scatter factor is present in most pleural effusion fluids from cancer patients

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12 December 2020

Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer

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12 December 2020

Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene

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12 December 2020

The Met proto-oncogene mesenchymal to epithelial cell conversion

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12 December 2020

Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma

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12 December 2020

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

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12 December 2020

Scatter factor and hepatocyte growth factor: activities, properties, and mechanism

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12 December 2020

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

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12 December 2020

Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network

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12 December 2020

Overexpression of the Met/HGF receptor in ovarian cancer.

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12 December 2020

Levels of the human hepatocyte growth factor in serum of patients with various liver diseases determined by an enzyme-linked immunosorbent assay

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12 December 2020

Expression of scatter factor in human bladder carcinoma.

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12 December 2020

Regulation of scatter factor production via a soluble inducing factor

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12 December 2020

Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells

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12 December 2020

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

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12 December 2020

Proteolytic activation of a single-chain precursor of hepatocyte growth factor by extracellular serine-protease

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12 December 2020

Tyrosine phosphorylation of beta-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells

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12 December 2020

Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma.

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12 December 2020

Purification and characterization of hepatocyte growth factor (HGF)-converting enzyme: activation of pro-HGF

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12 December 2020

Hepatocyte growth factor transforms immortalized mouse liver epithelial cells

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12 December 2020

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

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12 December 2020

Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas

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12 December 2020

Effect of hepatocyte growth factor on the expression of E- and P-cadherin in gastric carcinoma cell lines

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12 December 2020

c-met proto-oncogene expression in benign and malignant human prostate tissues

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12 December 2020

A role for HGF/SF in neural induction and its expression in Hensen's node during gastrulation

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12 December 2020

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor

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12 December 2020

Regulation of fibroblast hepatocyte growth factor/scatter factor expression by human breast carcinoma cell lines and peptide growth factors

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12 December 2020

Helper-independent transformation by unintegrated Harvey sarcoma virus DNA

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12 December 2020

Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts

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12 December 2020

The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors

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12 December 2020

Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines.

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12 December 2020

The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras.

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12 December 2020

The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein

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12 December 2020

The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit

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12 December 2020

Immunohistochemical detection of hepatocyte growth factor/scatter factor in human cancerous and inflammatory lesions of various organs.

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12 December 2020

The met proto-oncogene receptor and lumen formation

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12 December 2020

Regulation of scatter factor (hepatocyte growth factor) production by tumor-stroma interaction

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12 December 2020

Autophosphorylation promotes complex formation of recombinant hepatocyte growth factor receptor with cytoplasmic effectors containing SH2 domains

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12 December 2020

Tumor cytotoxic activity of HGF-SF.

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12 December 2020

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

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12 December 2020

The c-met/HGF receptor in human tumours.

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12 December 2020

Hepatocyte growth factor stimulates invasion across reconstituted basement membranes by a new human small intestinal cell line

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12 December 2020

C127 cells resistant to transformation by tyrosine protein kinase oncogenes

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12 December 2020

A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis

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12 December 2020

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

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12 December 2020

Expression of the c-Met/HGF receptor in human melanocytic neoplasms: demonstration of the relationship to malignant melanoma tumour progression

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12 December 2020

Identifiers

DOI

10.1007/S001090050053

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28 September 2017

1 reference

PubMed ID

8892055