(Q41191925)

English

The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

scientific article published on June 1996

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scholarly article

1 reference

Europe PubMed Central

28 September 2017

The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (English)

1 reference

Europe PubMed Central

28 September 2017

1 reference

ChEBI release 2020-05-28

author name string

Berkhout TA

1

1 reference

Europe PubMed Central

28 September 2017

Simon HM

2

1 reference

Europe PubMed Central

28 September 2017

Patel DD

3

1 reference

Europe PubMed Central

28 September 2017

Bentzen C

4

1 reference

Europe PubMed Central

28 September 2017

Niesor E

5

1 reference

Europe PubMed Central

28 September 2017

Jackson B

6

1 reference

Europe PubMed Central

28 September 2017

Suckling KE

7

1 reference

Europe PubMed Central

28 September 2017

language of work or name

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publication date

1 June 1996

1 reference

Europe PubMed Central

28 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

28 September 2017

271

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Europe PubMed Central

28 September 2017

14376-14382

1 reference

Europe PubMed Central

28 September 2017

24

1 reference

Europe PubMed Central

28 September 2017

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase function in alpha-toxin-perforated cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Treatment of CHO-K1 cells with 25-hydroxycholesterol produces a more rapid loss of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity than can be accounted for by enzyme turnover

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

The effect of (-)-hydroxycitrate on the activity of the low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase levels in the human hepatoma cell line Hep G2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Co-ordinate regulation of low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase and synthase gene expression in HepG2 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Regulation of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA contents in human hepatoma cell line Hep G2 by distinct classes of mevalonate-derived metabolites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Modulation of the enzymic activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase by multiple kinase systems involving reversible phosphorylation: a review

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis in Syrian hamster C100 cells by mevinolin, 25-hydroxycholesterol, and mevalonate: the role of posttranscriptional control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Irreversible inactivation of 3-hydroxy-3-methylglutaryl-CoA reductase by H2O2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Low-density-lipoprotein-receptor mRNA content of fibroblasts from normal and familial hypercholesterolaemic subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Phosphorylation and inactivation of HMG-CoA reductase at the AMP-activated protein kinase site in response to fructose treatment of isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

The effect of inhibitors of free radical generating-enzymes on low-density lipoprotein oxidation by macrophages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.24.14376

21 January 2018

Identifiers

10.1074/JBC.271.24.14376

1 reference

Europe PubMed Central

28 September 2017

1 reference

Europe PubMed Central

28 September 2017

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