(Q41205948)

28 September 2017

1 reference

title

The role of the cell cycle in genitourinary carcinoma (English)

1 reference

28 September 2017

T W McGarvey

1

1 reference

PubMed ID

8912471

28 September 2017

S B Malkowicz

series ordinal

2

1 reference

28 September 2017

1 January 1996

1 reference

28 September 2017

World Journal of Urology

1 reference

28 September 2017

14

1 reference

28 September 2017

310-317

1 reference

28 September 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1007/bf00184603

28 September 2017

0 references

cites work

CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1.

1 reference

12 December 2020

P16 gene in uncultured tumours

1 reference

12 December 2020

Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins

1 reference

12 December 2020

Homozygous deletion of the MTS1/p16 and MTS2/p15 genes and amplification of the CDK4 gene in glioma.

1 reference

12 December 2020

Amplification at chromosome 11q13 in transitional cell tumours of the bladder.

1 reference

12 December 2020

Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas

1 reference

12 December 2020

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

12 December 2020

Human epithelial ovarian cancer allelotype.

1 reference

12 December 2020

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

1 reference

12 December 2020

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

1 reference

12 December 2020

Overexpression of cyclin D1 enhances gene amplification

1 reference

12 December 2020

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining

1 reference

12 December 2020

Low levels of expression of an inhibitor of cyclin-dependent kinases (CIP1/WAF1) in primary breast carcinomas with p53 mutations

1 reference

12 December 2020

Reduced expression of TGF beta is associated with advanced disease in transitional cell carcinoma

1 reference

12 December 2020

The ubiquitin-proteasome proteolytic pathway

1 reference

12 December 2020

Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases

1 reference

12 December 2020

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

1 reference

12 December 2020

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

1 reference

12 December 2020

Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer

1 reference

12 December 2020

Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma

1 reference

12 December 2020

Proliferating cell nuclear antigen is required for DNA excision repair

1 reference

12 December 2020

Expression of cyclin DI in human prostate cancer cell lines

1 reference

12 December 2020

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

12 December 2020

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase

1 reference

12 December 2020

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

12 December 2020

Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer

1 reference

12 December 2020

Absence of WAF1 mutations in a variety of human malignancies

1 reference

12 December 2020

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

12 December 2020

p21 is necessary for the p53-mediated G1 arrest in human cancer cells

1 reference

12 December 2020

Morphometric grading of bladder tumors in comparison with histologic grading by pathologists

1 reference

12 December 2020

p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma.

1 reference

12 December 2020

Mutational analysis of CDKN2 (CDK4I/MTS1) gene in tissues and cell lines of human prostate cancer

1 reference

12 December 2020

Differential expression of transforming growth factor-beta 1 and beta 3 as well as c-fos mRNA in normal human prostate, benign prostatic hyperplasia and prostatic cancer

1 reference

12 December 2020

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

12 December 2020

Heterogeneity in intratumor distribution of p53 mutations in human prostate cancer

1 reference

12 December 2020

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

1 reference

12 December 2020

A mutant p21 cyclin-dependent kinase inhibitor isolated from a Burkitt's lymphoma.

1 reference

12 December 2020

Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways

1 reference

12 December 2020

Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles

1 reference

12 December 2020

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

1 reference

12 December 2020

Tumor suppression by p21WAF1

1 reference

12 December 2020

Implication of cell kinetic changes during the progression of human prostatic cancer

1 reference

12 December 2020

p53 is mutated in a subset of advanced-stage prostate cancers

1 reference

12 December 2020

Concurrent amplification of cyclin E and CDK2 genes in colorectal carcinomas

1 reference

12 December 2020

In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations preferentially in non-small cell lung cancers

1 reference

12 December 2020

Increased levels of p21WAF1/Cip1 in human brain tumors.

1 reference

12 December 2020

The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo

1 reference

12 December 2020

p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors

1 reference

12 December 2020

The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas

1 reference

12 December 2020

p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.

1 reference

12 December 2020

CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines

1 reference

12 December 2020

MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation

1 reference

12 December 2020

p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade, and stage in bladder cancer

1 reference

12 December 2020

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

12 December 2020

High frequency of chromosome 9p allelic loss and CDKN2 tumor suppressor gene alterations in squamous cell carcinoma of the bladder

1 reference

12 December 2020

Deletion of the p16 and p15 Genes in Human Bladder Tumors

1 reference

12 December 2020

Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product

1 reference

12 December 2020

Small Subgroup of Aggressive, Highly Proliferative Prostatic Carcinomas Defined by p53 Accumulation

1 reference

12 December 2020

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

1 reference

12 December 2020

Alterations of the p53 gene are common and critical events for the maintenance of malignant phenotypes in small-cell lung carcinoma

1 reference

12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

12 December 2020

p53 protein accumulation and gene mutation in the progression of human prostate carcinoma

1 reference

12 December 2020

Involvement of CDKN2 (p16INK4A/MTS1) and p15INK4B/MTS2 in human leukemias and lymphomas.

1 reference

12 December 2020

Molecular analysis of the Cip1/Waf1 (p21) gene in diverse types of human tumors

1 reference

12 December 2020

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

12 December 2020

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1 reference

12 December 2020

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

12 December 2020

Association of immunohistochemical staining for p53 with metastatic progression and poor survival in patients with renal cell carcinoma

1 reference

12 December 2020

Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase

1 reference

12 December 2020

1 reference

12 December 2020

Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.

1 reference

12 December 2020

Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4

1 reference

12 December 2020

WAF1, a potential mediator of p53 tumor suppression

1 reference

12 December 2020

Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21.

1 reference

12 December 2020

Expression of p21WAF1/CIP1 is heterogeneous and unrelated to proliferation index in human ovarian carcinoma

1 reference

12 December 2020

Direct interaction of Gadd45 with PCNA and evidence for competitive interaction of Gadd45 and p21Waf1/Cip1 with PCNA

1 reference

12 December 2020

The role of p34 kinases in the G1 to S-phase transition

1 reference

12 December 2020

Deletion of p16 and p15 genes in brain tumors

1 reference

12 December 2020

Allelotype of human ovarian cancer

1 reference

12 December 2020

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

1 reference

12 December 2020

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

1 reference

12 December 2020

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

1 reference

12 December 2020

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1 reference

12 December 2020

Dependence of cyclin E-CDK2 kinase activity on cell anchorage.

1 reference

12 December 2020

Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases

1 reference

12 December 2020

Mutations in the p16INK4/MTS1/CDKN2, p15INK4B/MTS2, and p18 genes in primary and metastatic lung cancer

1 reference

12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

12 December 2020

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

1 reference

12 December 2020

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

1 reference

12 December 2020

Alterations of the p27KIP1 gene in non-Hodgkin's lymphomas and adult T-cell leukemia/lymphoma

1 reference

12 December 2020

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

1 reference

12 December 2020

A cell cycle-regulated inhibitor of cyclin-dependent kinases

1 reference

12 December 2020

Allelotype of renal cell carcinoma

1 reference

12 December 2020

p53 in prostate cancer: frequent expressed transition mutations

1 reference

12 December 2020

Induction of WAF1/CIP1 by a p53-independent pathway

1 reference

12 December 2020

Cytogenetics of non-small cell lung cancer: analysis of consistent non-random abnormalities

1 reference

12 December 2020

Expression and amplification of cyclin genes in human breast cancer

1 reference

12 December 2020

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00184603

1 reference

PubMed ID

8912471

Dimensions Publication ID

28 September 2017

0 references

1 reference

PubMed ID

8912471