(Q41222940)

28 September 2017

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title

Somatic diversification of antibody responses (English)

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28 September 2017

B Zheng

1

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28 September 2017

G Kelsoe

series ordinal

2

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28 September 2017

S Han

series ordinal

3

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28 September 2017

publication date

1 January 1996

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Journal of Clinical Immunology

28 September 2017

published in

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28 September 2017

volume

16

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28 September 2017

issue

1

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28 September 2017

page(s)

1-11

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Distribution of mutations around rearranged heavy-chain antibody variable-region genes

28 September 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF01540967

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF01540967

The organization of the mouse Igh-V locus. Dispersion, interspersion, and the evolution of VH gene family clusters

21 January 2018

1 reference

12 December 2020

Polymorphism in anti-phosphocholine antibodies reflecting evolution of immunoglobulin families

1 reference

12 December 2020

Developmentally controlled expression of immunoglobulin VH genes

1 reference

12 December 2020

Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

1 reference

12 December 2020

Maturation of the immune response in germinal centers

1 reference

12 December 2020

1 reference

12 December 2020

Effect of thymus cell injections on germinal center formation in lymphoid tissues of nude (thymusless) mice.

1 reference

12 December 2020

B-cell commitment and diversification in the bursa of Fabricius

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12 December 2020

Maturation and dispersal of B-cell clones during T cell-dependent antibody responses

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12 December 2020

Stepwise intraclonal maturation of antibody affinity through somatic hypermutation

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12 December 2020

A linkage map of the mouse immunoglobulin lambda light chain locus

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12 December 2020

Cell population kinetics of the germinal centres of lymph nodes of BALB/c mice

1 reference

12 December 2020

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

12 December 2020

How immunoglobulin V kappa genes rearrange

1 reference

12 December 2020

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells

1 reference

12 December 2020

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

1 reference

12 December 2020

B lymphocytes may escape tolerance by revising their antigen receptors

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12 December 2020

VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE

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12 December 2020

Apoptosis is associated with the extensive B cell death in the sheep ileal Peyer's patch and the chicken bursa of Fabricius: a possible role in B cell selection

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12 December 2020

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

1 reference

12 December 2020

Locus-specific somatic hypermutation in germinal centre T cells

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12 December 2020

Antibody response to a T-dependent antigen requires B cell expression of complement receptors

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12 December 2020

How B and T cells talk to each other

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12 December 2020

gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory

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12 December 2020

The evolution of B-cell clones

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12 December 2020

Position of the rearranged V kappa and its 5' flanking sequences determines the location of somatic mutations in the J kappa locus

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12 December 2020

The path of memory B-cell development

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12 December 2020

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

1 reference

12 December 2020

Immigration of thoracic duct B lymphocytes into established germinal centers in the rat.

1 reference

12 December 2020

CD40 ligand and its role in X-linked hyper-IgM syndrome

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12 December 2020

Germinal centres and the B-cell system. V. Presence of germinal centre-precursor cells among lymphocytes of the thoracic duct in the rat

1 reference

12 December 2020

Age-dependent variations of antibody avidity

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12 December 2020

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

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12 December 2020

Cellular bases for relative radioresistance of the antibody-forming system at advanced stages of the secondary response to tetanus toxoid in mice.

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12 December 2020

Is rapid proliferation in B centroblasts linked to somatic mutation in memory B cell clones?

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12 December 2020

T cells within germinal centers are specific for the immunizing antigen

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12 December 2020

Humoral immune responses in CD40 ligand-deficient mice

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12 December 2020

Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

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12 December 2020

Ig VH hypermutation is absent in the germinal centers of aged mice

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12 December 2020

Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci

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12 December 2020

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

1 reference

12 December 2020

B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells

1 reference

12 December 2020

Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation

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12 December 2020

Aged T cells are hyporesponsive to costimulation mediated by CD28.

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12 December 2020

Mutation drift and repertoire shift in the maturation of the immune response

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12 December 2020

Among naive precursor cell subpopulations only progenitors of memory B cells originate germinal centers

1 reference

12 December 2020

Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice

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12 December 2020

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

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12 December 2020

Kinetics of germinal center development in lymph nodes of young and aging immune mice

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12 December 2020

Antigen-driven B cell differentiation in vivo

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12 December 2020

Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo

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12 December 2020

A shared kappa reciprocal fragment and a high frequency of secondary Jk5 rearrangements among influenza hemagglutinin specific B cell hybridomas

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12 December 2020

Receptor editing: an approach by autoreactive B cells to escape tolerance

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12 December 2020

The generation of memory cells. I. The role of C3 in the generation of B memory cells

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12 December 2020

Germinal centres in T-cell-dependent antibody responses

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12 December 2020

The Follicular Dendritic Cell: Long Term Antigen Retention During Immunity

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12 December 2020

The maturation of the immune response

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12 December 2020

Germinal centers develop oligoclonally

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12 December 2020

Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments

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12 December 2020

Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation

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12 December 2020

Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations.

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12 December 2020

The order and orientation of mouse lambda-genes explain lambda-rearrangement patterns

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12 December 2020

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

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12 December 2020

The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

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12 December 2020

Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

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12 December 2020

Biased expression of JH-proximal VH genes occurs in the newly generated repertoire of neonatal and adult mice

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12 December 2020

Mice lacking MHC class II molecules

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12 December 2020

Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers.

1 reference

12 December 2020

Selection for B cells with productive IgL gene rearrangements occurs in the bursa of Fabricius during chicken embryonic development

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12 December 2020

The central role of follicular dendritic cells in lymphoid tissues

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12 December 2020

Somatic diversification of immunoglobulin heavy chain VDJ genes: evidence for somatic gene conversion in rabbits

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12 December 2020

Distinct pathways of B cell differentiation. I. Residual T cells in athymic mice support the development of splenic germinal centers and B cell memory without an induction of antibody

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12 December 2020

Somatic diversification of the chicken immunoglobulin light chain gene is limited to the rearranged variable gene segment

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12 December 2020

Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens

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12 December 2020

Relationship of germinal centers in lymphoid tissue to immunologic memory. VI. Transfer of B cell memory with lymph node cells fractionated according to their receptors for peanut agglutinin.

1 reference

12 December 2020

Germinal centres and the origin of the B-cell system. II. Germinal centres in the rabbit spleen and popliteal lymph nodes

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12 December 2020

Clones of B lymphocytes: their natural selection and expansion

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12 December 2020

Double recombination of a single immunoglobulin kappa-chain allele: implications for the mechanism of rearrangement

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12 December 2020

Rabbit IgH sequences in appendix germinal centers: VH diversification by gene conversion-like and hypermutation mechanisms

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12 December 2020

The follicular dendritic cell: its role in antigen presentation in the generation of immunological memory

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12 December 2020

The evolution and involution of Peyer's patches in fetal and postnatal sheep.

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12 December 2020

CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome

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12 December 2020

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

1 reference

12 December 2020

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39

1 reference

12 December 2020

CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells

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12 December 2020

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

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12 December 2020

Facultative role of germinal centers and T cells in the somatic diversification of IgVH genes

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12 December 2020

Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice

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12 December 2020

Sites of B-cell activation in vivo

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12 December 2020

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

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12 December 2020

Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles

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12 December 2020

Evidence of extensive lymphocyte death in sheep Peyer's patches. I. A comparison of lymphocyte production and export

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12 December 2020

Recruitment of virgin B cells into an immune response is restricted to activation outside lymphoid follicles.

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12 December 2020

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

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12 December 2020

RAG-2 expression is not essential for chicken immunoglobulin gene conversion

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12 December 2020

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

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12 December 2020

The role of CD40 in the regulation of humoral and cell-mediated immunity

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12 December 2020

Receptor editing in self-reactive bone marrow B cells

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12 December 2020

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

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12 December 2020

Mechanism of antigen-driven selection in germinal centres

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12 December 2020

DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus

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12 December 2020

Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen

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12 December 2020

Patterns of somatic mutations in immunoglobulin variable genes

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12 December 2020

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions

1 reference

12 December 2020

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

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12 December 2020

Immunologicc activity of the aged.

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12 December 2020

In vitro immune response to the 2,4,6-trinitrophenyl determinant in aged C57BL/6J mice:changes in the humoral immune response to, avidity for the TNP determinant and responsiveness to LPS effect with aging

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12 December 2020

Immunologic deficiencies in senescence. I. Characterization of intrinsic deficiencies

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12 December 2020

Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches

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12 December 2020

Intraclonal generation of antibody mutants in germinal centres

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12 December 2020

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. 1993.

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12 December 2020

Analysis of somatic mutation in five B cell subsets of human tonsil

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12 December 2020

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance

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12 December 2020

Rearrangement of chicken immunoglobulin genes is not an ongoing process in the embryonic bursa of Fabricius

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12 December 2020

Humoral immunity in aging

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12 December 2020

A hyperconversion mechanism generates the chicken light chain preimmune repertoire

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12 December 2020

The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation

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12 December 2020

Follicular dendritic cells as accessory cells

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12 December 2020

The chicken B cell compartment

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12 December 2020

Altered VH gene segment utilization in the response to phosphorylcholine by aged mice

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12 December 2020

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers

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12 December 2020

Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process

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12 December 2020

T lymphocytes in rat germinal centres belong to an ER3+ subpopulation of CD4+ cells

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12 December 2020

Identifiers

DOI

10.1007/BF01540967

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Dimensions Publication ID

28 September 2017

1040279176

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