(Q41226404)

English

Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice

scientific article published on 12 December 2011

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scholarly article

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Europe PubMed Central

PMC publication ID

28 September 2017

Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice (English)

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

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Peter J. Ratcliffe

6

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Europe PubMed Central

PMC publication ID

28 September 2017

author name string

Zoi Michailidou

1

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Europe PubMed Central

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28 September 2017

Sophie Turban

2

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28 September 2017

Eileen Miller

3

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Europe PubMed Central

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28 September 2017

Xiantong Zou

4

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Europe PubMed Central

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28 September 2017

Joerg Schrader

5

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Europe PubMed Central

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28 September 2017

Patrick W F Hadoke

7

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Europe PubMed Central

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28 September 2017

Brian R Walker

8

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Europe PubMed Central

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28 September 2017

John P Iredale

9

1 reference

Europe PubMed Central

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28 September 2017

Nicholas M Morton

10

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28 September 2017

Jonathan R Seckl

11

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28 September 2017

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publication date

12 December 2011

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28 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

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28 September 2017

287

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Europe PubMed Central

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28 September 2017

6

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Europe PubMed Central

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28 September 2017

4188-4197

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Europe PubMed Central

PMC publication ID

28 September 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3281676/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Regulation of HIF-1{alpha} activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia

1 reference

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Hypoxia-inducible factor-1 (HIF-1)-independent microvascular angiogenesis in the aged rat brain

1 reference

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Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescence

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Evolving challenges in hepatic fibrosis

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Improved heart function follows enhanced inflammatory cell recruitment and angiogenesis in 11betaHSD1-deficient mice post-MI.

1 reference

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Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis

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Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes

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Enhanced angiogenesis in obesity and in response to PPARgamma activators through adipocyte VEGF and ANGPTL4 production

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Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

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Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

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Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

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Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ

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Preventing local regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1 enhances angiogenesis

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Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor.

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EPAS1 promotes adipose differentiation in 3T3-L1 cells

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Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

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A transgenic model of visceral obesity and the metabolic syndrome

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Tissue-specific dysregulation of cortisol metabolism in human obesity

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Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

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Identifiers

10.1074/JBC.M111.259325

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

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