(Q41232968)

28 September 2017

1 reference

title

Mechanisms of action of atypical antipsychotic drugs: a critical analysis (English)

1 reference

28 September 2017

B J Kinon

1

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PubMed ID

8935797

28 September 2017

J A Lieberman

series ordinal

2

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28 September 2017

1 March 1996

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28 September 2017

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28 September 2017

124

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28 September 2017

2-34

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28 September 2017

1-2

1 reference

https://scigraph.springernature.com/pub.10.1007/bf02245602

28 September 2017

0 references

cites work

Effect of clozapine on the turnover of dopamine in the corpus striatum and in the limbic system.

1 reference

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Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London

21 January 2018

1 reference

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Differential effect of neuroleptic drugs on dopamine turnover in the extrapyramidal and limbic system

21 January 2018

1 reference

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Effects of clozapine on cerebral catecholaminergic neurone systems

21 January 2018

1 reference

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Suppression of dyskinesias in advanced Parkinson's disease. II. Increasing daily clozapine doses suppress dyskinesias and improve parkinsonism symptoms

21 January 2018

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Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Regional differences in homovanillic acid concentrations after acute and chronic administration of antipsychotic drugs

21 January 2018

1 reference

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Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures

21 January 2018

1 reference

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Clozapine: a 2-year open trial in Parkinson's disease patients with psychosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Dreams, Hallucinogenic Drug States, and Schizophrenia: A Psychological and Biological Comparison

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

The role of excitatory amino acids in neuropsychiatric illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Amelioration of negative symptoms in schizophrenia by glycine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Dopamine release and metabolism in the rat frontal cortex, nucleus accumbens, and striatum: a comparison of acute clozapine and haloperidol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Clozapine treatment of parkinsonism with psychosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Opposite regulation of serotonin-S2 and dopamine-D2 receptors in rat brain following chronic receptor blockade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Prospective study of psychobiology in first-episode schizophrenia at Hillside Hospital.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Clinical effects of clozapine in chronic schizophrenia: response to treatment and predictors of outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Analysis of the D4 Dopamine Receptor Gene Variant in an Italian Schizophrenia Kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Risperidone in the treatment of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Reversal of neuroleptic-induced catalepsy by novel aryl-piperazine anxiolytic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

The Mechanism of Action of Novel Antipsychotic Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Zacopride in schizophrenia: a single-blind serotonin type 3 antagonist trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Effects of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Peripheral and central adrenoceptor modulation of the behavioural effects of clozapine in the paw test

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Interaction of clozapine with the histamine H3 receptor in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Negative symptoms and hypofrontality in chronic schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02245602

Autoradiographic analysis of regional alterations in brain receptors following chronic administration and withdrawal of typical and atypical neuroleptics in rats

21 January 2018

1 reference

12 December 2020

Dopamine D4 receptor variants in unrelated schizophrenic cases and controls

1 reference

12 December 2020

Therapeutic effect of clozapine in psychotic decompensation in idiopathic Parkinson's disease

1 reference

12 December 2020

Caudate nuclei volumes in schizophrenic patients treated with typical antipsychotics or clozapine

1 reference

12 December 2020

Neuroleptics have identical potencies in human brain limbic and putamen regions

1 reference

12 December 2020

A controlled dose-ranging study of remoxipride and haloperidol in schizophrenia--a Canadian multicentre trial

1 reference

12 December 2020

Chronic clozapine treatment decreases 5-hydroxytryptamine1C receptor density in the rat choroid plexus: comparison with haloperidol.

1 reference

12 December 2020

Alterations in mRNA levels of D2 receptors and neuropeptides in striatonigral and striatopallidal neurons of rats with neuroleptic-induced dyskinesias.

1 reference

12 December 2020

Differences in dopamine release and metabolism in rat striatal subregions following acute clozapine using in vivo microdialysis.

1 reference

12 December 2020

Effect of drugs influencing central serotonergic mechanisms on haloperidol-induced catalepsy

1 reference

12 December 2020

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex

1 reference

12 December 2020

Differential alteration of striatal D-1 and D-2 receptors induced by the long-term administration of haloperidol, sulpiride or clozapine to rats.

1 reference

12 December 2020

Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat.

1 reference

12 December 2020

Regulation of cortical and subcortical glutamate receptor subunit expression by antipsychotic drugs

1 reference

12 December 2020

Proceedings: Stereospecificity of neuroleptic effects in the 10-piperazino-10, 11-dihydrodibenzo (b, f) thiepin series

1 reference

12 December 2020

Quinolinic acid lesions of rat striatum abolish D1- and D2-dopamine receptor-mediated catalepsy

1 reference

12 December 2020

Cross-sensitization between foot shock stress and enkephalin-induced motor activity

1 reference

12 December 2020

Acute thioridazine stimulates mesolimbic but not nigrostriatal dopamine release: demonstration by in vivo electrochemistry

1 reference

12 December 2020

Effect of thioridazine, clozapine and other antipsychotics on the kinetic state of tyrosine hydroxylase and on the turnover rate of dopamine in striatum and nucleus accumbens

1 reference

12 December 2020

Partial benzodiazepine agonists in schizophrenia: expectations and present clinical findings

1 reference

12 December 2020

5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone

1 reference

12 December 2020

3-methoxytyramine and different neuroleptics: Dissociation from HVA and DOPAC

1 reference

12 December 2020

Repeated atypical neuroleptic administration: effects on central dopamine metabolism monitored by in vivo voltammetry

1 reference

12 December 2020

Effects of acute thioridazine, metoclopramide and SCH 23390 on the basal activity of A9 and A10 dopamine cells

1 reference

12 December 2020

Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.

1 reference

12 December 2020

D2 dopamine receptor messenger RNA is altered to a greater extent by blockade of glutamate receptors than by blockade of dopamine receptors.

1 reference

12 December 2020

Atypical neuroleptic-like behavioral effects of neurotensin.

1 reference

12 December 2020

Antagonism by 8-OH-DPAT, but not ritanserin, of catalepsy induced by SCH 23390 in the rat

1 reference

12 December 2020

The limbic functional selectivity of amperozide is not mediated by dopamine D2 receptors as assessed by in vitro and in vivo binding.

1 reference

12 December 2020

Effects of thioridazine on apomorphine-elicited stereotypic behavior and motor activity

1 reference

12 December 2020

Studies on the role of catecholamines in the frontal cortex [proceedings]

1 reference

12 December 2020

Clozapine treatment and its effect on neuroendocrine responses induced by the serotonin agonist, m-chlorophenylpiperazine

1 reference

12 December 2020

Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primate prefrontal cortex

1 reference

12 December 2020

Behavioral aspects of serotonin-dopamine interaction in the monkey

1 reference

12 December 2020

Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double-blind comparative study

1 reference

12 December 2020

Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs

1 reference

12 December 2020

Biochemical methods for predicting the occurrence of tardive dyskinesia

1 reference

12 December 2020

D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients

1 reference

12 December 2020

Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia

1 reference

12 December 2020

Chronic treatment with clozapine selectively decreases basal dopamine release in nucleus accumbens but not in caudate-putamen as measured by in vivo brain microdialysis: further evidence for depolarization block

1 reference

12 December 2020

Differential changes in serotonin 5-HT1A and 5-HT2 receptor binding in patients with chronic schizophrenia

1 reference

12 December 2020

Effects of zotepine, haloperidol and clozapine on MK-801-induced stereotypy and locomotion in rats

1 reference

12 December 2020

Clozapine: a hypothesised mechanism for its unique clinical profile

1 reference

12 December 2020

D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

1 reference

12 December 2020

Glycine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label, pilot study.

1 reference

12 December 2020

Genetic study of dopamine D1, D2, and D4 receptors in schizophrenia

1 reference

12 December 2020

Electrophysiological profile of the new atypical neuroleptic, sertindole, on midbrain dopamine neurones in rats: acute and repeated treatment

1 reference

12 December 2020

Comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat.

1 reference

12 December 2020

Influence of antipsychotics and serotonin antagonists on presynaptic receptors modulating the release of serotonin in synaptosomes of the nucleus accumbens of rats

1 reference

12 December 2020

Neuroleptic action of clozapine injected into various brain areas in rats.

1 reference

12 December 2020

Effects on striatal and mesolimbic dopamine systems of a new potential antipsychotic drug -mezilamine- with weak cataleptogenic properties

1 reference

12 December 2020

Serotonergic aspects of acute extrapyramidal syndromes in nonhuman primates

1 reference

12 December 2020

Correlation between tryptophan hydroxylase activity in the brain and predisposition to pinch-induced catalepsy in mice

1 reference

12 December 2020

Serotonin-dopamine interactions in the nigrostriatal system

1 reference

12 December 2020

Spiperone: a ligand of choice for neuroleptic receptors. 2. Regional distribution and in vivo displacement of neuroleptic drugs

1 reference

12 December 2020

The relative importance of dopamine and norepinephrine in mediating locomotor activity

1 reference

12 December 2020

Serotonin2/1C receptor activation causes a localized expression of the immediate-early gene c-fos in rat brain: evidence for involvement of dorsal raphe nucleus projection fibres

1 reference

12 December 2020

Clozapine and sulpiride up-regulate dopamine D3 receptor mRNA levels.

1 reference

12 December 2020

The effects of clozapine on neurocognition: an overview.

1 reference

12 December 2020

Regional blockade by neuroleptic drugs ofin vivo 3H-spiperone binding in the rat brain. Relation to blockade of apomorphine induced hyperactivity and stereotypies

1 reference

12 December 2020

Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia

1 reference

12 December 2020

High 5-HT2 receptor occupancy in clozapine treated patients demonstrated by PET.

1 reference

12 December 2020

The effects of haloperidol and clozapine on extracellular GABA levels in the prefrontal cortex of the rat: an in vivo microdialysis study.

1 reference

12 December 2020

The effect of clozapine on cognition and psychiatric symptoms in patients with schizophrenia.

1 reference

12 December 2020

Expression of the proneurotensin gene in the rat brain and its regulation by antipsychotic drugs

1 reference

12 December 2020

Effect of serotonin antagonism in schizophrenia: a pilot study with setoperone.

1 reference

12 December 2020

Clozapine response and plasma catecholamines and their metabolites

1 reference

12 December 2020

Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions.

1 reference

12 December 2020

Antagonism of AP-5-induced sniffing stereotypy links umespirone to atypical antipsychotics

1 reference

12 December 2020

Coexpression of neurotensin and c-fos mRNAs in rat neostriatal neurons following acute haloperidol

1 reference

12 December 2020

[3H]Clozapine is not a suitable radioligand for the labelling of D4 dopamine receptors in postmortem human brain.

1 reference

12 December 2020

Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine

1 reference

12 December 2020

Effect of selective 5-HT1A agonists and 5-HT2 antagonists on inherited catalepsy in rats

1 reference

12 December 2020

Effects of haloperidol and low dose clozapine on the acetylcholine turnover rate in rat forebrain structures.

1 reference

12 December 2020

Dopamine receptor pharmacology

1 reference

12 December 2020

Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat

1 reference

12 December 2020

Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine

1 reference

12 December 2020

The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys

1 reference

12 December 2020

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

1 reference

12 December 2020

The depolarization block hypothesis of neuroleptic action: implications for the etiology and treatment of schizophrenia

1 reference

12 December 2020

Long-term treatment with low doses of the D1 antagonist NNC 756 and the D2 antagonist raclopride in monkeys previously exposed to dopamine antagonists

1 reference

12 December 2020

Distribution of putative D4 dopamine receptors in postmortem striatum from patients with schizophrenia.

1 reference

12 December 2020

Akathisia and clozapine treatment

1 reference

12 December 2020

Optimal dose of neuroleptic in acute schizophrenia. A controlled study of the neuroleptic threshold and higher haloperidol dose

1 reference

12 December 2020

Schizophrenia and the D1 receptor: focus on negative symptoms

1 reference

12 December 2020

Clozapine and haloperidol produce a differential pattern of immediate early gene expression in rat caudate-putamen, nucleus accumbens, lateral septum and islands of Calleja.

1 reference

12 December 2020

Modulation by dopaminergic and serotonergic systems of cholinergic interneurons in nucleus accumbens and striatum.

1 reference

12 December 2020

Neuroendocrine profile of SDZ HDC-912 and OPC-4392, two new atypical antipsychotic drugs, in schizophrenic patients

1 reference

12 December 2020

Effects of citalopram, a specific serotonin uptake inhibitor, in tardive dyskinesia and parkinsonism.

1 reference

12 December 2020

Regional displacement by sulpiride of [3H]spiperone binding in vivo. Biochemical and behavioural evidence for a preferential action of limbic and nigral dopamine receptors

1 reference

12 December 2020

The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent

1 reference

12 December 2020

Reduced cataleptogenic effects of some neuroleptics in rats with lesioned midbrain raphe and treated with p-chlorophenylalanine.

1 reference

12 December 2020

Differential effects after repeated treatment with haloperidol, clozapine, thioridazine and tefludazine on SNC and VTA dopamine neurones in rats.

1 reference

12 December 2020

Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine

1 reference

12 December 2020

Remoxipride and haloperidol in schizophrenia: a double-blind multicentre study

1 reference

12 December 2020

Effect of ritanserin on the interaction of amfonelic acid and neuroleptic-induced striatal dopamine metabolism

1 reference

12 December 2020

Glycine site antagonists abolish dopamine D2 but not D1 receptor mediated catalepsy in rats

1 reference

12 December 2020

Serotonergic involvement in haloperidol-induced catalepsy

1 reference

12 December 2020

Dopamine D2 receptor blockade in vivo with the novel antipsychotics risperidone and remoxipride — an123I-IBZM single photon emission tomography (SPET) study

1 reference

12 December 2020

Effects of typical and atypical neuroleptics on Fos protein expression in the rat forebrain

1 reference

12 December 2020

Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia

1 reference

12 December 2020

Haloperidol-induced catalepsy is mediated by postsynaptic dopamine receptors

1 reference

12 December 2020

Interaction of psychotropic drugs with central 5-HT3 recognition sites: fact or artifact?

1 reference

12 December 2020

Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects

1 reference

12 December 2020

Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain

1 reference

12 December 2020

Clozapine. A novel antipsychotic agent

1 reference

12 December 2020

Serotonergic and dopaminergic aspects of neuroleptic-induced extrapyramidal syndromes in nonhuman primates

1 reference

12 December 2020

Double blind comparative study of remoxipride and haloperidol in acute schizophrenic patients

1 reference

12 December 2020

Selective antidopaminergic properties of remoxiprid, a new potential antipsychotic agent

1 reference

12 December 2020

The effects of clozapine, thioridazine and phenoxybenzamine on the action of drugs stimulating the central catecholamine receptors

1 reference

12 December 2020

Dopamine D1 receptor antagonism in schizophrenia: is there reduced risk of extrapyramidal side-effects?

1 reference

12 December 2020

Clozapine attenuates N-methyl-D-aspartate receptor complex-mediated responses in vivo: tentative evidence for a functional modulation by a noradrenergic mechanism

1 reference

12 December 2020

Functional coupling of human D2, D3, and D4 dopamine receptors in HEK293 cells

1 reference

12 December 2020

Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes

1 reference

12 December 2020

Presynaptic dopamine release is enhanced by 5-HT3 receptor activation in medial prefrontal cortex of freely moving rats.

1 reference

12 December 2020

Regional differences in the induction of behavioral supersensitivity by prolonged treatment with atypical neuroleptics

1 reference

12 December 2020

Binding of typical and atypical antipsychotic agents to transiently expressed 5-HT1C receptors

1 reference

12 December 2020

Serotonin-dopamine interaction in the rat ventral tegmental area: an electrophysiological study in vivo

1 reference

12 December 2020

On the relevance of preferential increases of mesolimbic versus striatal dopamine turnover for the prediction of antipsychotic activity of psychotropic drugs

1 reference

12 December 2020

D1 and D2 dopamine receptor-mediated mechanisms and behavioral supersensitivity

1 reference

12 December 2020

Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain

1 reference

12 December 2020

The effect of typical and atypical antipsychotic drugs on the stimulation of phosphoinositide hydrolysis produced by the 5-HT3 receptor agonist 2-methyl-serotonin

1 reference

12 December 2020

Differential alterations in striatal dopamine receptor sensitivity induced by repeated administration of clinically equivalent doses of haloperidol, sulpiride or clozapine in rats

1 reference

12 December 2020

Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine

1 reference

12 December 2020

The effect of different types of cortical lesions on drug-induced catalepsy in rats: a pharmacological analysis.

1 reference

12 December 2020

Effects of dopamine receptor stimulants on locomotor activity of rats with electrolytic or 6-hydroxydopamine-induced lesions of the nucleus accumbens

1 reference

12 December 2020

Selective reduction of extracellular dopamine in the rat nucleus accumbens following chronic treatment with DAU 6215, a 5-HT3 receptor antagonist

1 reference

12 December 2020

Effect of neuroleptic medication on cerebrospinal fluid monoamine metabolite concentrations in schizophrenia. Serotonin-dopamine interactions as a target for treatment

1 reference

12 December 2020

m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients. Evidence implicating serotonergic systems in the positive symptoms of schizophrenia

1 reference

12 December 2020

Risperidone for hallucinations in levodopa-treated Parkinson's disease patients

1 reference

12 December 2020

Evidence for a selective brain noradrenergic involvement in the locomotor stimulant effects of amphetamine in the rat.

1 reference

12 December 2020

Clinical and electroencephalographic effects of methoclopramide in psychiatry

1 reference

12 December 2020

The effects of haloperidol and raclopride in the paw test are influenced similarly by SCH 39166

1 reference

12 December 2020

Metoclopramide: antipsychotic efficacy of a drug lacking potency in receptor models

1 reference

12 December 2020

Effect of chronic treatment with NNC 756, a new D-1 receptor antagonist, or raclopride, a D-2 receptor antagonist, in drug-naive Cebus monkeys: dystonia, dyskinesia and D-1/D-2 supersensitivity

1 reference

12 December 2020

8-Hydroxy-2-(di-n-propylamino) tetralin, a selective serotonin1A receptor agonist, blocks haloperidol-induced catalepsy by an action on raphe nuclei medianus and dorsalis

1 reference

12 December 2020

Effects of D-cycloserine and (+)-HA-966 on the locomotor stimulation induced by NMDA antagonists and clonidine in monoamine-depleted mice

1 reference

12 December 2020

Dopamine D2 receptors and dopamine metabolism. Relationship between biochemical and behavioural effects of substituted benzamide drugs.

1 reference

12 December 2020

Evaluation of a stable CCK agonist (A68552) in conditioned avoidance responding in mice, rats, and primates: comparison with typical and atypical antipsychotics

1 reference

12 December 2020

Multiunit activity from the A9 and A10 areas in rats following chronic treatment with different neuroleptic drugs

1 reference

12 December 2020

Selective D1- and D2-dopamine receptor blockade both induces akathisia in humans--a PET study with [11C]SCH 23390 and [11C]raclopride

1 reference

12 December 2020

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1 reference

12 December 2020

Influence of drugs on striatal and limbic homovanillic acid concentration in the rat brain

1 reference

12 December 2020

The current status of the dopamine hypothesis of schizophrenia

1 reference

12 December 2020

Chronic clozapine treatment of rats down-regulates cortical 5-HT2 receptors

1 reference

12 December 2020

The effects of dopamine D1 and D2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment

1 reference

12 December 2020

Pharmacology and neurochemistry of buspirone

1 reference

12 December 2020

Influence of median raphe nucleus lesions on neuroleptic-induced catalepsy and on the anticataleptic effect of buspirone.

1 reference

12 December 2020

Effect of clozapine on the metabolism of serotonin in rat brain

1 reference

12 December 2020

Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications

1 reference

12 December 2020

3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873).

1 reference

12 December 2020

Influence of alpha 1-adrenoceptor antagonism of ketanserin on the nature of its 5-HT2 receptor antagonism

1 reference

12 December 2020

Clozapine: selective labeling of sites resembling 5HT6 serotonin receptors may reflect psychoactive profile.

1 reference

12 December 2020

3-Methoxytyramine is the major metabolite of released dopamine in the rat frontal cortex: reassessment of the effects of antipsychotics on the dynamics of dopamine release and metabolism in the frontal cortex, nucleus accumbens, and striatum by a si

1 reference

12 December 2020

IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTIC DRUGS (MAJOR TRANQUILLIZERS) FROM ANIMAL DATA?I. "NEUROLEPTIC ACTIVITY SPECTRA" FOR RATS

1 reference

12 December 2020

Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine.

1 reference

12 December 2020

Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia.

1 reference

12 December 2020

Apomorphine-antagonism in rats

1 reference

12 December 2020

Ibotenic acid lesion of the ventral hippocampus differentially affects dopamine and its metabolites in the nucleus accumbens and prefrontal cortex in the rat.

1 reference

12 December 2020

Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain dopamine neurons.

1 reference

12 December 2020

Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment

1 reference

12 December 2020

Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats

1 reference

12 December 2020

1 reference

12 December 2020

Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutamatergic pathways? (Hypothesis)

1 reference

12 December 2020

Clozapine: neuroleptic-induced EPS and tardive dyskinesia

1 reference

12 December 2020

Mianserin treatment of patients with psychosis induced by antiparkinsonian drugs

1 reference

12 December 2020

Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine

1 reference

12 December 2020

Haloperidol but not clozapine increases neurotensin receptor mRNA levels in rat substantia nigra

1 reference

12 December 2020

Acute effects of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat: an in vivo microdialysis study

1 reference

12 December 2020

Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine

1 reference

12 December 2020

Are Striatal Dopamine D4 Receptors Increased in Schizophrenia?

1 reference

12 December 2020

Neuroleptic malignant syndrome induced by nemonapride

1 reference

12 December 2020

D1- and D2-receptor antagonists induce catalepsy via different efferent striatal pathways [corrected].

1 reference

12 December 2020

Further studies on the effects of chronic clozapine on regional extracellular dopamine levels in the brain of conscious rats

1 reference

12 December 2020

Psychosis and positron tomography

1 reference

12 December 2020

Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy of serotonin2 and dopamine2 receptors

1 reference

12 December 2020

Dopamine D1 (SCH 23390) and D2 (haloperidol) antagonists in drug-naive monkeys

1 reference

12 December 2020

Open pilot trial of ritanserin in parkinsonism.

1 reference

12 December 2020

Dopamine D4 receptors elevated in schizophrenia

1 reference

12 December 2020

Risperidone versus haloperidol in the treatment of chronic schizophrenic patients: a parallel group double-blind comparative trial

1 reference

12 December 2020

4-Piperazinyl-10H-thieno[2,3-b][1,5]benzodiazepines as potential neuroleptics

1 reference

12 December 2020

Effect of chronic treatment with SCH 23390 and haloperidol on spontaneous activity of dopamine neurones in substantia nigra pars compacta (SNC) and ventral tegmental area (VTA) in rats.

1 reference

12 December 2020

The effect of OPC-4392, a partial dopamine receptor agonist on negative symptoms: results of an open study.

1 reference

12 December 2020

Selective inhibition of mesolimbic dopamine release following chronic administration of clozapine: involvement of α1-noradrenergic receptors demonstrated by in vivo voltammetry

1 reference

12 December 2020

In vivo potencies of antipsychotic drugs in blocking alpha 1 noradrenergic and dopamine D2 receptors: implications for drug mechanisms of action

1 reference

12 December 2020

In vivo dopamine-D2 and serotonin-5-HT2 receptor binding study of risperidone and haloperidol.

1 reference

12 December 2020

Serotonin denervation enhances responsiveness of presynaptic dopamine efflux to acute clozapine in nucleus accumbens but not in caudate-putamen

1 reference

12 December 2020

Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neuroleptics

1 reference

12 December 2020

Comparison of chronic administration of haloperidol and the atypical neuroleptics, clozapine and raclopride, in an animal model of tardive dyskinesia

1 reference

12 December 2020

The CCK-A receptor antagonist devazepide but not the CCK-B receptor antagonist L-365,260 reverses the effects of chronic clozapine and haloperidol on midbrain dopamine neurons

1 reference

12 December 2020

Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei

1 reference

12 December 2020

A double-blind multicentre study comparing remoxipride, two and three times daily, with haloperidol in schizophrenia

1 reference

12 December 2020

Clozapine treatment of psychosis in Parkinson's disease: a report of five consecutive cases.

1 reference

12 December 2020

Seroquel (ICI 204 636), a putative "atypical" antipsychotic, in schizophrenia with positive symptomatology: results of an open clinical trial and changes of neuroendocrinological and EEG parameters

1 reference

12 December 2020

Further studies of the mechanism behind scopolamine-induced reversal of antistereotypic and cataleptogenic effects of neuroleptics in rats.

1 reference

12 December 2020

Alleles at the dopamine D4 receptor locus do not contribute to the genetic susceptibility to schizophrenia in a large Swedish kindred

1 reference

12 December 2020

1 reference

12 December 2020

Dopamine release in n. accumbens and striatum by clozapine: simultaneous monitoring by in vivo electrochemistry

1 reference

12 December 2020

Haloperidol-induced morphological changes in striatum are associated with glutamate synapses.

1 reference

12 December 2020

Molecular neuroanatomic mechanisms of Parkinson's disease: a proposed therapeutic approach

1 reference

12 December 2020

Differential effects of amfonelic acid on the haloperidol- and clozapine-induced increase in extracellular DOPAC in the nucleus accumbens and the striatum

1 reference

12 December 2020

Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone.

1 reference

12 December 2020

Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons.

1 reference

12 December 2020

Studies on the stereoselective dopamine receptor blockade in the rat brain by rigid spiro amines

1 reference

12 December 2020

Neuroleptic affinities for human brain receptors and their use in predicting adverse effects

1 reference

12 December 2020

Survey on the pharmacodynamics of the new antipsychotic risperidone

1 reference

12 December 2020

Behavioral profile of raclopride in agonistic encounters between male mice

1 reference

12 December 2020

Differential actions of classical and atypical neuroleptics on mouse nigrostriatal neurons.

1 reference

12 December 2020

Effect of antipsychotic drugs on the firing of dorsal raphe cells. I. Role of adrenergic system

1 reference

12 December 2020

Burst firing in dopamine neurons induced by N-methyl-D-aspartate: role of electrogenic sodium pump

1 reference

12 December 2020

B-HT 920--a novel dopamine autoreceptor agonist in the treatment of patients with schizophrenia

1 reference

12 December 2020

Pizotifen (Sandomigran) used in the treatment of parkinsonian tremor (preliminary communication)

1 reference

12 December 2020

Risperidone in the treatment of chronic schizophrenic patients: an international double-blind parallel-group study versus haloperidol. The International Risperidone Research Group

1 reference

12 December 2020

Dopamine receptors and the dopamine hypothesis of schizophrenia

1 reference

12 December 2020

Sertindole, a new neuroleptic with extreme selectivity on A10 versus A9 dopamine neurones in the rat.

1 reference

12 December 2020

Effects of chronic treatment of haloperidol and clozapine on levels of G-protein subunits in rat striatum

1 reference

12 December 2020

The effect of the partial dopamine agonist terguride on negative symptoms in schizophrenics

1 reference

12 December 2020

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1 reference

12 December 2020

Chronic clozapine treatment down-regulates serotonin 5-HT-1c receptors in rat brain

1 reference

12 December 2020

Electrophysiological, biochemical, and behavioral studies of acute haloperidol-induced depolarization block of nigral dopamine neurons

1 reference

12 December 2020

Subcortical excitatory amino acid levels after acute and subchronic administration of typical and atypical neuroleptics.

1 reference

12 December 2020

Systemic administration of amperozide, a new atypical antipsychotic drug, preferentially increases dopamine release in the rat medial prefrontal cortex.

1 reference

12 December 2020

Evidence for specific interactions between 5-HT1A and dopamine D2 receptor mechanisms in the mediation of extrapyramidal motor functions in the rat

1 reference

12 December 2020

Effects of acute and chronic clozapine and haloperidol administration on 3-methoxytyramine accumulation in rat prefrontal cortex, nucleus accumbens and striatum.

1 reference

12 December 2020

Central noradrenaline depletion attenuates amphetamine-induced locomotor behavior.

1 reference

12 December 2020

Differential effects of acute clozapine and haloperidol on the activity of ventral tegmental (A10) and nigrostriatal (A9) dopamine neurons

1 reference

12 December 2020

Glutamate in schizophrenics and healthy controls

1 reference

12 December 2020

Neurotensin-dopamine interactions: relevance to schizophrenia and the action of antipsychotic drugs

1 reference

12 December 2020

Iontophoretically administered drugs acting at the N-methyl-D-aspartate receptor modulate burst firing in A9 dopamine neurons in the rat

1 reference

12 December 2020

Positron emission tomography with (18F)methylspiperone demonstrates D2 dopamine receptor binding differences of clozapine and haloperidol

1 reference

12 December 2020

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1 reference

12 December 2020

Acute administration of clozapine, thioridazine and metoclopramide increases extracellular DOPAC and decreases extracellular 5-HIAA, measured in the nucleus accumbens and striatum of the rat using in vivo voltammetry

1 reference

12 December 2020

Remoxipride and raclopride differ from metoclopramide by their effects on striatal dopamine release and biosynthesis in rats.

1 reference

12 December 2020

Effects of typical and atypical antipsychotic drugs on two-way active avoidance. Relationship to DA receptor blocking profile.

1 reference

12 December 2020

The effect of chronic clozapine and haloperidol on basal dopamine release and metabolism in rat striatum and nucleus accumbens studied by in vivo microdialysis

1 reference

12 December 2020

Clozapine and the Dopamine Hypothesis of Schizophrenia, a Critical Appraisal

1 reference

12 December 2020

Atypical neuroleptics clozapine and thioridazine enhance amphetamine-induced stereotypy

1 reference

12 December 2020

Distribution of dopaminergic receptors in the primate cerebral cortex: quantitative autoradiographic analysis using [3H]raclopride, [3H]spiperone and [3H]SCH23390.

1 reference

12 December 2020

Effects of prazosin on the dopaminergic neurotransmission in rat brain

1 reference

12 December 2020

Brain catecholamines in schizophrenia -- a good case for noradrenaline.

1 reference

12 December 2020

Risperidone: clinical development: north American results

1 reference

12 December 2020

Prevalence and severity of akathisia in patients on clozapine

1 reference

12 December 2020

Zotepine reversibly induces akinesia and rigidity in Parkinson's disease patients with resting tremor or drug-induced psychosis

1 reference

12 December 2020

Clozapine improves dizocilpine-induced delayed alteration impairment in rats

1 reference

12 December 2020

Chronic fluphenazine and clozapine elicit opposite changes in brain muscarinic receptor binding: implications for understanding tardive dyskinesia.

1 reference

12 December 2020

Clozapine efficacy in schizophrenic nonresponders

1 reference

12 December 2020

Dopamine uptake sites and dopamine receptors in Parkinson's disease and schizophrenia

1 reference

12 December 2020

Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics

1 reference

12 December 2020

Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: antagonism by atypical antipsychotic drugs.

1 reference

12 December 2020

Serotonergic modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis

1 reference

12 December 2020

The Role of Serotonin Receptor Subtypes in the Behavioural Effects of Neuroleptic Drugs. A Paw Test Study in Rats

1 reference

12 December 2020

A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic systems

1 reference

12 December 2020

Clozapine decreases enkephalin mRNA in rat striatum

1 reference

12 December 2020

Behavioral and biochemical correlates after haloperidol and clozapine long-term treatment

1 reference

12 December 2020

Quantitative light microscopic demonstration of increased pallidal and striatal met5-enkephalin-like immunoreactivity in rats following chronic treatment with haloperidol but not with clozapine: implications for the pathogenesis of neuroleptic-induc

1 reference

12 December 2020

A Canadian multicenter placebo-controlled study of fixed doses of risperidone and haloperidol in the treatment of chronic schizophrenic patients

1 reference

12 December 2020

Locus coeruleus norepinephrine-containing neurons: effects produced by acute and subchronic treatment with antipsychotic drugs and amphetamine.

1 reference

12 December 2020

Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs

1 reference

12 December 2020

A double-blind multicentre comparison of remoxipride, at two dose levels, and haloperidol

1 reference

12 December 2020

Antagonism of AP-5- and amphetamine-induced behaviour by timelotem as compared with clozapine and haloperidol

1 reference

12 December 2020

Neuropsychopharmacological profile in rodents of SR 57746A, a new, potent 5-HT1A receptor agonist

1 reference

12 December 2020

Comparison of the effect of substituted benzamides on midbrain dopamine neurones after treatment of rats for 21 days.

1 reference

12 December 2020

Altered striatal function in a mutant mouse lacking D1A dopamine receptors

1 reference

12 December 2020

Prefrontal sulcal prominence is inversely related to response to clozapine in schizophrenia

1 reference

12 December 2020

Dopamine increase in the prefrontal cortex correlates with reversal of haloperidol-induced catalepsy in rats

1 reference

12 December 2020

L-dopa helps positive but not negative features of neuroleptic-insensitive chronic schizophrenia.

1 reference

12 December 2020

Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex

1 reference

12 December 2020

Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects

1 reference

12 December 2020

Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens

1 reference

12 December 2020

Subjective response to neuroleptics and the quality of life: implications for treatment outcome

1 reference

12 December 2020

Human dopamine D4 receptor gene: frequent occurrence of a null allele and observation of homozygosity.

1 reference

12 December 2020

Dopamine D2 and D3 receptor preferring antagonists differentially affect striatal dopamine release and metabolism in conscious rats

1 reference

12 December 2020

Subcortical dopamine and serotonin turnover during acute and subchronic administration of typical and atypical neuroleptics.

1 reference

12 December 2020

The effect of serotonergic agents on haloperidol-induced catalepsy

1 reference

12 December 2020

Dopaminergic neurons: An in vivo system for measuring drug interactions with presynaptic receptors

1 reference

12 December 2020

Effects of amphetamine and apomorphine on locomotor activity after kainic acid lesion of the nucleus accumbens septi in the rat.

1 reference

12 December 2020

The pharmacological characterisation of pilocarpine-induced purposeless chewing behaviour in the rat

1 reference

12 December 2020

Behavioral evidence for supersensitivity after chronic administration of haloperidol, clozapine, and thioridazine

1 reference

12 December 2020

Scopolamine attenuates haloperidol-induced c-fos expression in the striatum

1 reference

12 December 2020

Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat.

1 reference

12 December 2020

Effects of six months of clozapine treatment on the quality of life of chronic schizophrenic patients

1 reference

12 December 2020

Motor and mental aspects of acute extrapyramidal syndromes.

1 reference

12 December 2020

Behavioral effects of amphetamine and apomorphine after striatal lesions in the rat

1 reference

12 December 2020

On the mechanism of central action of amphetamine: The role of catecholamines

1 reference

12 December 2020

Cerebral Glutamate, Neuroleptic Drugs and Schizophrenia: Increase of Cerebrospinal Fluid Glutamate Levels and Decrease of Striate Body Glutamate Levels following Sulpiride Treatment in Rats

1 reference

12 December 2020

Beta-adrenoceptor antagonists in neuropsychiatry: an update

1 reference

12 December 2020

Intermediate affinity and potency of clozapine and low affinity of other neuroleptics and of antidepressants at H3 receptors

1 reference

12 December 2020

Receptor occupancy by ritanserin and risperidone measured using ex vivo autoradiography

1 reference

12 December 2020

Long-term clinical and social outcome studies in schizophrenia in relation to the cognitive and emotional side effects of antipsychotic drugs.

1 reference

12 December 2020

Dopamine and schizophrenia

1 reference

12 December 2020

The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine (clozapine)

1 reference

12 December 2020

On the anticataleptic action of cyproheptadine

1 reference

12 December 2020

Role of 5-HT in the action of some drugs affecting extrapyramidal system.

1 reference

12 December 2020

Adjunctive fluoxetine in the treatment of negative symptoms in chronic schizophrenic patients

1 reference

12 December 2020

Clozapine inhibits limbic system kindling: implications for antipsychotic action.

1 reference

12 December 2020

Effects of acute and chronic treatments with clozapine and haloperidol on serotonin (5-HT2) and dopamine (D2) receptors in the rat brain

1 reference

12 December 2020

Polymorphic tandem repeats in dopamine D4 receptor are spread over primate species.

1 reference

12 December 2020

Activity of tryptophan hydroxylase in brain of hereditary predisposed to catalepsy rats

1 reference

12 December 2020

U-66444B and U-68553B, potent autoreceptor agonists at dopaminergic cell bodies and terminals.

1 reference

12 December 2020

Cataleptogenic potency of the antipsychotic drugs is inversely correlated with neuronal activity in the amygdaloid complex of the rat.

1 reference

12 December 2020

Behavioral, anti-dopaminergic, and prohypnotic effects of neuroleptics during and after prolonged treatment

1 reference

12 December 2020

Endogenous dopamine lowers the dopamine D2 receptor density as measured by [3H]raclopride: implications for positron emission tomography of the human brain

1 reference

12 December 2020

Neurochemical effects of chronic co-administration of ritanserin and haloperidol: comparison with clozapine effects.

1 reference

12 December 2020

Apomorphine does not reverse reduced basal dopamine release in rat striatum and nucleus accumbens after chronic haloperidol treatment.

1 reference

12 December 2020

The effects of clozapine and fluperlapine on the in vivo release and metabolism of dopamine in the striatum and in the prefrontal cortex of freely moving rats

1 reference

12 December 2020

Anti-glutamatergic effects of clozapine

1 reference

12 December 2020

Risperidone versus perphenazine in the treatment of chronic schizophrenic patients with acute exacerbations

1 reference

12 December 2020

Clozapine inhibits serotoninergic transmission by an action at alpha 1-adrenoceptors not at 5-HT1A receptors.

1 reference

12 December 2020

The dopaminergic, glutamatergic, GABAergic bases for the action of amphetamine and cocaine.

1 reference

12 December 2020

Understanding the mechanism of action of atypical antipsychotic drugs. A review of compounds in use and development

1 reference

12 December 2020

Detection of dopaminergic supersensitivity induced by neuroleptic drugs in mice

1 reference

12 December 2020

Extrastriatal dopamine D2 receptors: distribution, pharmacological characterization and region-specific regulation by clozapine

1 reference

12 December 2020

Modulatory effect of clozapine on levodopa response in Parkinson's disease: a preliminary study

1 reference

12 December 2020

Basic biology of clozapine: electrophysiological and neuroendocrinological studies

1 reference

12 December 2020

On the significance of regional dopamine metabolism in the rat brain for the classification of centrally acting drugs.

1 reference

12 December 2020

Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats

1 reference

12 December 2020

Effects of olanzapine and other antipsychotic agents on responding maintained by a conflict schedule

1 reference

12 December 2020

Partial brain dopamine D2 receptor agonists in the treatment of schizophrenia.

1 reference

12 December 2020

Dopamine in the nucleus accumbens: preferential increase of DA turnover by rat prolactin

1 reference

12 December 2020

Haloperidol and clozapine treatment and their effect on M-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine

1 reference

12 December 2020

Treatment with clozapine and its effect on plasma homovanillic acid and norepinephrine concentrations in schizophrenia

1 reference

12 December 2020

Antagonism by neuroleptics of neurotransmitter receptors of normal human brain in vitro

1 reference

12 December 2020

Prazosin, a specific alpha1-noradrenergic receptor antagonist, has no effect on symptoms but increases autonomic arousal in schizophrenic patients

1 reference

12 December 2020

[Changes in the serotonin system of the brains of rats genetically predisposed to catalepsy]

1 reference

12 December 2020

Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of action

1 reference

12 December 2020

Pharmacologic properties of (-)-3PPP (preclamol) in man

1 reference

12 December 2020

3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors

1 reference

12 December 2020

Chronic treatment with classical and atypical antipsychotic drugs differentially decreases dopamine release in striatum and nucleus accumbens in vivo

1 reference

12 December 2020

Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics

1 reference

12 December 2020

Cholecystokinin (CCK) and schizophrenia: the selective CCKB antagonist LY262691 decreases midbrain dopamine unit activity.

1 reference

12 December 2020

Differential Fos-protein induction in rat forebrain regions after acute and long-term haloperidol and clozapine treatment

1 reference

12 December 2020

Loxapine and clozapine decrease serotonin (S2) but do not elevate dopamine (D2) receptor numbers in the rat brain.

1 reference

12 December 2020

Haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus accumbens as simultaneously measured by microdialysis

1 reference

12 December 2020

Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism

1 reference

12 December 2020

Inhibitory effects of ventral tegmental area stimulation on the activity of prefrontal cortical neurons: evidence for the involvement of both dopaminergic and GABAergic components

1 reference

12 December 2020

Ritanserin, a selective 5-HT2/1C antagonist, and negative symptoms in schizophrenia. A placebo-controlled double-blind trial

1 reference

12 December 2020

A double-blind comparative study of remoxipride and thioridazine in the acute phase of schizophrenia

1 reference

12 December 2020

Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations.

1 reference

12 December 2020

Synergy between a selective D1 antagonist and a selective D2 antagonist in the induction of catalepsy

1 reference

12 December 2020

Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition.

1 reference

12 December 2020

Comparative Psychotropic Effects of Metoclopramide and Prochlorperazine in Normal Subjects

1 reference

12 December 2020

The involvement of sigma and phencyclidine receptors in the action of antipsychotic drugs

1 reference

12 December 2020

An animal model for coexisting tardive dyskinesia and tardive parkinsonism: a glutamate hypothesis for tardive dyskinesia.

1 reference

12 December 2020

Long-term treatment with antipsychotics does not alter the phosphoinositide response to muscarinic or D2 dopaminergic agonists in rat striatum

1 reference

12 December 2020

Effects of lesions in the ventral noradrenergic bundle on behavior and response to psychotropic drugs in rats

1 reference

12 December 2020

Atypical neuroleptics suppress dopaminergic behavioral supersensitivity

1 reference

12 December 2020

Chronic treatment with clozapine, unlike haloperidol, does not induce changes in striatal D-2 receptor function in the rat.

1 reference

12 December 2020

[The level of catecholamines and dihydroxyphenylacetic acid in the brain of rats with a hereditary predisposition to catalepsy]

1 reference

12 December 2020

Risperidone: clinical safety and efficacy in schizophrenia

1 reference

12 December 2020

Differential effects of typical and atypical neuroleptics on alpha-noradrenergic and dopaminergic postsynaptic receptors

1 reference

12 December 2020

The comparative efficacy and long-term effect of clozapine treatment on neuropsychological test performance.

1 reference

12 December 2020

Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat.

1 reference

12 December 2020

Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: studies with chronic clozapine and haloperidol.

1 reference

12 December 2020

Comparison of circling induced by unilateral intrastriatal microinjections of haloperidol, clozapine and CCK-8 in rats.

1 reference

12 December 2020

The selective dopamine D2 receptor antagonist raclopride discriminates between dopamine-mediated motor functions.

1 reference

12 December 2020

Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography

1 reference

12 December 2020

An open clinical and biochemical study of ritanserin in acute patients with schizophrenia.

1 reference

12 December 2020

5-HT2 antagonist ritanserin in neuroleptic-induced parkinsonism: a double-blind comparison with orphenadrine and placebo.

1 reference

12 December 2020

Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum

1 reference

12 December 2020

Topographic intermingling of striatonigral and striatopallidal neurons in the rhesus monkey

1 reference

12 December 2020

Antipsychotic drugs: differential effects on dopamine neurons in basal ganglia and mesocortex following chronic administration in human and nonhuman primates

1 reference

12 December 2020

Dopaminergic supersensitivity in striatum and olfactory tubercle following chronic administration of haloperidol or clozapine

1 reference

12 December 2020

Effects of the sigma receptor ligand SR 31742A on neurotensin biosynthesis in rat basal ganglia

1 reference

12 December 2020

Dopamine receptors and transporters in Parkinson's disease and schizophrenia.

1 reference

12 December 2020

Effect of neuroleptics on endogenous norepinephrine in rat brain.

1 reference

12 December 2020

Time course of dopamine1,2 and serotonin2 receptor binding of antipsychotics in vivo

1 reference

12 December 2020

Identification of the neural systems subserving the actions of clozapine: clues from immediate-early gene expression

1 reference

12 December 2020

Differential Effects of Classical and Atypical Antipsychotic Drugs on A9 and A10 Dopamine Neurons

1 reference

12 December 2020

A hypervariable segment in the human dopamine receptor D4 (DRD4) gene.

1 reference

12 December 2020

Glutamatergic neurons projecting to the nucleus accumbens can affect motor functions in opposite directions depending on the dopaminergic tone

1 reference

12 December 2020

Possible mechanisms by which repeated clozapine administration differentially affects the activity of two subpopulations of midbrain dopamine neurons.

1 reference

12 December 2020

Effects of acute and chronic clozapine on dopaminergic function in medial prefrontal cortex of awake, freely moving rats

1 reference

12 December 2020

Frontal cortex lesions modify the cataleptogenic properties of haloperidol but not of clozapine

1 reference

12 December 2020

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values

1 reference

12 December 2020

Effects of chronic administration of neuroleptic and anticholinergic agents on densities of D2 dopamine and muscarinic cholinergic receptors in rat striatum.

1 reference

12 December 2020

Effects of terguride, a partial D2 agonist, on MPTP-lesioned parkinsonian cynomolgus monkeys

1 reference

12 December 2020

Seroquel: electrophysiological profile of a potential atypical antipsychotic.

1 reference

12 December 2020

Comparison of the effects of various typical and atypical antipsychotic drugs on the suppressant action of 2-methylserotonin on medial prefrontal cortical cells in the rat

1 reference

12 December 2020

Chronic treatment with clozapine or haloperidol differentially regulates dopamine and serotonin receptors in rat brain

1 reference

12 December 2020

Differential influence of haloperidol and sulpiride on dopamine receptors and peptide mRNA levels in the rat striatum and pituitary.

1 reference

12 December 2020

Interaction between clozapine and a lipophilic alpha 1-adrenergic agonist

1 reference

12 December 2020

Atypical antipsychotics, clozapine and sulpiride do not antagonise amphetamine-induced stereotyped locomotion

1 reference

12 December 2020

5-HT2A serotonin receptors in the brain of rats and mice hereditarily predisposed to catalepsy

1 reference

12 December 2020

Activation of 5-HT3 receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens

1 reference

12 December 2020

Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats

1 reference

12 December 2020

Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors

1 reference

12 December 2020

Biphasic displacement of [3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics.

1 reference

12 December 2020

Remoxipride, a new selective D2 antagonist, and haloperidol in cebus monkeys

1 reference

12 December 2020

Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats.

1 reference

12 December 2020

The use of benzodiazepines for psychotic disorders: a literature review and preliminary clinical findings

1 reference

12 December 2020

Treatment of drug-induced psychosis in Parkinson's disease with clozapine.

1 reference

12 December 2020

Serotonergic involvement with neuroleptic catalepsy

1 reference

12 December 2020

Sexual behavior increases c-fos expression in the forebrain of the male rat

1 reference

12 December 2020

Effects of serotonergic and anticholinergic drugs in haloperidol-induced dystonia in Cebus monkeys.

1 reference

12 December 2020

Clozapine--a serotonin antagonist?

1 reference

12 December 2020

Differential locomotor interactions between dopamine D1/D2 receptor agonists and the NMDA antagonist dizocilpine in monoamine-depleted mice

1 reference

12 December 2020

Common profile of D1 receptor antagonists and atypical antipsychotic drugs revealed by analysis of dopamine turnover.

1 reference

12 December 2020

The effect of clozapine on plasma norepinephrine: relationship to clinical efficacy

1 reference

12 December 2020

Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo

1 reference

12 December 2020

Idazoxan, an alpha 2 antagonist, augments fluphenazine in schizophrenic patients: a pilot study.

1 reference

12 December 2020

Spontaneous activity of A9 and A10 dopamine neurons after acute and chronic administration of the selective dopamine D-1 receptor antagonist SCH 23390

1 reference

12 December 2020

Effects of the 5-HT receptor antagonists cyanopindolol, ICI 169,369, cisapride and granisetron on neuroleptic-induced catalepsy in mice

1 reference

12 December 2020

Clozapine use in diffuse Lewy body disease

1 reference

12 December 2020

A double blind comparative multicentre study of remoxipride and haloperidol in schizophrenia.

1 reference

12 December 2020

Correlation between drug-induced supersensitivity of dopamine dependent striatal mechanisms and the increase in striatal content of the Ca2+ regulated protein activator of cAMP phosphodiesterase

1 reference

12 December 2020

PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients

1 reference

12 December 2020

Identification of receptor domains that modify ligand binding to 5-hydroxytryptamine2 and 5-hydroxytryptamine1c serotonin receptors

1 reference

12 December 2020

Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors

1 reference

12 December 2020

d-Cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label study

1 reference

12 December 2020

D1 and D2 dopamine receptors differentially regulate c-fos expression in striatonigral and striatopallidal neurons

1 reference

12 December 2020

CSF noradrenergic activity and sleep EEG in clinically stable schizophrenic patients after haloperidol withdrawal

1 reference

12 December 2020

Clozapine and haloperidol in the amygdaloid complex: differential effects on dopamine transmission with long-term treatment.

1 reference

12 December 2020

Double-blind comparison of risperidone and haloperidol in schizophrenic and schizoaffective psychoses.

1 reference

12 December 2020

Symptomatic relief from treatment-induced psychosis in Parkinson's disease: an open-label pilot study with remoxipride

1 reference

12 December 2020

Structure activity relationships for agonist and antagonist drugs at pre- and postsynaptic receptor sites in rat brain

1 reference

12 December 2020

Electrochemistry in vivo: application to CNS pharmacology

1 reference

12 December 2020

Remoxipride and haloperidol in the acute phase of schizophrenia: a double-blind comparison

1 reference

12 December 2020

Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area

1 reference

12 December 2020

Norepinephrine-dopamine interactions and behavior

1 reference

12 December 2020

Effect of centrally acting drugs on regional dopamine metabolism

1 reference

12 December 2020

Effects of antipsychotic drugs on 5-HT2 receptors in the medial prefrontal cortex: microiontophoretic studies

1 reference

12 December 2020

Effect of antipsychotic drugs on homovanillic acid levels in striatum and olfactory turbercle of the rat

1 reference

12 December 2020

Multiple dopamine D4 receptor variants in the human population

1 reference

12 December 2020

Increase of 3-methoxy-4-hydroxyphenylethylene glycol in rat brain by neuroleptic drugs

1 reference

12 December 2020

A double-blind comparative multicentre study of remoxipride and haloperidol in schizophrenia

1 reference

12 December 2020

Chronic mianserin treatment decreases 5-HT2 receptor binding without altering 5-HT2 receptor mRNA levels.

1 reference

12 December 2020

Enhancement of the in vivo binding of [3H]flunitrazepam by the atypical neuroleptic, clozapine

1 reference

12 December 2020

Postnatal development of a cholinergic influence on neuroleptic-induced catalepsy.

1 reference

12 December 2020

Quantitative autoradiography of striatal dopamine D1, D2 and re-uptake sites in rats with vacuous chewing movements.

1 reference

12 December 2020

An open-label trial of milacemide in schizophrenia: an NMDA intervention strategy.

1 reference

12 December 2020

Dopamine neurochemical profile of atypical antipsychotics resembles that of D-1 antagonists.

1 reference

12 December 2020

Detection of the neuroleptic properties of clozapine, sulpiride and thioridazine

1 reference

12 December 2020

Fluvoxamine improves negative symptoms in treated chronic schizophrenia: an add-on double-blind, placebo-controlled study

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02245602

1 reference

PubMed ID

8935797

Dimensions Publication ID

28 September 2017

0 references

1 reference

PubMed ID

8935797